Publications by authors named "Pengxin Chai"

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Visualizing the translation landscape in human cells at high resolution.
Wei Zheng, Yuekang Zhang, Jimin Wang, Shuhui Wang, Pengxin Chai

Nat Commun· November 2025

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The mechanochemical cycle of reactive full-length human dynein 1.
Pengxin Chai, Jun Yang, Indigo C Geohring, Steven M Markus, Yue Wang

Nat Struct Mol Biol· August 2025

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Nde1 promotes Lis1 binding to full-length autoinhibited human dynein 1.
Jun Yang, Yuanchang Zhao, Pengxin Chai, Ahmet Yildiz, Kai Zhang

Nat Chem Biol· August 2025

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Nde1 Promotes Lis1 Binding to Full-Length Autoinhibited Human Dynein-1.
Jun Yang, Yuanchang Zhao, Pengxin Chai, Ahmet Yildiz, Kai Zhang

bioRxiv· January 2025

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A nucleotide code governs Lis1's ability to relieve dynein autoinhibition.
Indigo C Geohring, Pengxin Chai, Bharat R Iyer, William D Ton, Jun Yang

bioRxiv· January 2025

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DNAHX: a novel, non-motile dynein heavy chain subfamily, identified by cryo-EM endogenously.
Pengxin Chai, Diego Suchenski Loustaunau, Wan Zheng, Jun Yang, Kai Zhang

bioRxiv· January 2025

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Molecular basis for the assembly of the dynein transport machinery on microtubules.
Qinhui Rao, Pengxin Chai, Kai Zhang

bioRxiv· December 2024

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High-resolution in situ structures of mammalian respiratory supercomplexes.
Wan Zheng, Pengxin Chai, Jiapeng Zhu, Kai Zhang

Nature· July 2024

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Visualizing the translation landscape in human cells at high resolution.
Wei Zheng, Yuekang Zhang, Jimin Wang, Shuhui Wang, Pengxin Chai

bioRxiv· July 2024

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High-resolution Structures of Mammalian Mitochondrial Respiratory Supercomplexes in Reaction within Native Mitochondria.
Wan Zheng, Pengxin Chai, Jiapeng Zhu, Kai Zhang

bioRxiv· April 2024

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LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility.
Jae Yeon Hwang, Pengxin Chai, Shoaib Nawaz, Jungmin Choi, Francesc Lopez-Giraldez

Elife· December 2023

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Abl2 repairs microtubules and phase separates with tubulin to promote microtubule nucleation.
Daisy Duan, Wanqing Lyu, Pengxin Chai, Shaojie Ma, Kuanlin Wu

Curr Biol· November 2023

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LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility.
Jae Yeon Hwang, Pengxin Chai, Shoaib Nawaz, Jungmin Choi, Francesc Lopez-Giraldez

bioRxiv· September 2023

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Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
William D Ton, Yue Wang, Pengxin Chai, Cisloynny Beauchamp-Perez, Nicholas T Flint

Nat Struct Mol Biol· September 2023

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Author Correction: Cryo-EM structure of an active central apparatus.
Long Han, Qinhui Rao, Renbin Yang, Yue Wang, Pengxin Chai

Nat Struct Mol Biol· April 2023

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High-Resolution Structural Analysis of Dyneins by Cryo-electron Microscopy.
Pengxin Chai, Qinhui Rao, Yue Wang, Kai Zhang

Methods Mol Biol· January 2023

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Multi-curve fitting and tubulin-lattice signal removal for structure determination of large microtubule-based motors.
Pengxin Chai, Qinhui Rao, Kai Zhang

J Struct Biol· December 2022

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Structures of a mobile intron retroelement poised to attack its structured DNA target.
Kevin Chung, Ling Xu, Pengxin Chai, Junhui Peng, Swapnil C Devarkar

Science· November 2022

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Cryo-EM structure of an active central apparatus.
Long Han, Qinhui Rao, Renbin Yang, Yue Wang, Pengxin Chai

Nat Struct Mol Biol· May 2022

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Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Qinhui Rao, Long Han, Yue Wang, Pengxin Chai, Yin-Wei Kuo

Nat Struct Mol Biol· October 2021

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