Publications by authors named "Per Sauerberg"

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Glucose-sensitive insulin with attenuation of hypoglycaemia.
Thomas Hoeg-Jensen, Thomas Kruse, Christian L Brand, Jeppe Sturis, Christian Fledelius, Per Sauerberg

Nature· October 2024

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Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls.
Lotte Simonsen, Jesper Lau, Thomas Kruse, Tingqing Guo, Jim McGuire, Per Sauerberg

PLoS One· April 2022

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Structure-activity relationships for negative allosteric mGluR5 modulators.
Birgitte H Kaae, Kasper Harpsøe, Trine Kvist, Jesper M Mathiesen, Christina Mølck, Per Sauerberg

ChemMedChem· March 2012

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PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.
Ji-Ming Ye, Jennifer Tid-Ang, Nigel Turner, Xiao-Yi Zeng, Hai-Yan Li, Per Sauerberg

Br J Pharmacol· June 2011

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Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.
Maria Sörhede Winzell, Erik Max Wulff, Grith Skytte Olsen, Per Sauerberg, Carsten F Gotfredsen

Eur J Pharmacol· January 2010

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Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone.
Philip J Larsen, Kirsten Lykkegaard, Leif K Larsen, Jan Fleckner, Per Sauerberg

Eur J Pharmacol· October 2008

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Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites.
Birgitte H Kaae, Kasper Harpsøe, Jette S Kastrup, Alberto Contreras Sanz, Darryl S Pickering, Per Sauerberg

Chem Biol· November 2007

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Novel selective PPARdelta agonists: optimization of activity by modification of alkynylallylic moiety.
Miroslav Havranek, Per Sauerberg, John P Mogensen, Pavel Kratina, Claus B Jeppesen

Bioorg Med Chem Lett· August 2007

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Design of a partial PPARdelta agonist.
Ingrid Pettersson, Søren Ebdrup, Miroslav Havranek, Pavel Pihera, Marek Korínek, Per Sauerberg

Bioorg Med Chem Lett· August 2007

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Design of potent PPARalpha agonists.
Per Sauerberg, John P Mogensen, Lone Jeppesen, Paul S Bury, Jan Fleckner

Bioorg Med Chem Lett· June 2007

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Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo.
Per Sauerberg, Grith S Olsen, Lone Jeppesen, John P Mogensen, Ingrid Pettersson

J Med Chem· April 2007

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Selective PPAR agonists for the treatment of type 2 diabetes.
Jan O Nehlin, John P Mogensen, Ingrid Petterson, Lone Jeppesen, Jan Fleckner, Per Sauerberg

Ann N Y Acad Sci· May 2006

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Structure-activity relationships of dimeric PPAR agonists.
Per Sauerberg, John P Mogensen, Lone Jeppesen, L Anders Svensson, Jan Fleckner

Bioorg Med Chem Lett· March 2005

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Prediction of PPAR-alpha ligand-mediated physiological changes using gene expression profiles.
Klaus Stensgaard Frederiksen, Erik Max Wulff, Per Sauerberg, John Patrick Mogensen, Lone Jeppesen

J Lipid Res· March 2004

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Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo.
Per Sauerberg, Paul S Bury, John P Mogensen, Heinz-Josef Deussen, Ingrid Pettersson

J Med Chem· November 2003

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Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.
Christian L Brand, Jeppe Sturis, Carsten F Gotfredsen, Jan Fleckner, Christian Fledelius, Per Sauerberg

Am J Physiol Endocrinol Metab· April 2003

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Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar.
Søren Ebdrup, Ingrid Pettersson, Hanne B Rasmussen, Heinz-Josef Deussen, Anette Frost Jensen, Per Sauerberg

J Med Chem· April 2003

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Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template.
John P Mogensen, Lone Jeppesen, Paul S Bury, Ingrid Pettersson, Jan Fleckner, Per Sauerberg

Bioorg Med Chem Lett· January 2003

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Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.
Per Sauerberg, Ingrid Pettersson, Lone Jeppesen, Paul S Bury, John P Mogensen

J Med Chem· February 2002

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