Publications by authors named "Peter A Edwards"

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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption.
Bethan L Clifford, Leslie R Sedgeman, Kevin J Williams, Pauline Morand, Angela Cheng, Peter A Edwards

Cell Metab· August 2021

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Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.
Moritz von Scheidt, Yuqi Zhao, Thomas Q de Aguiar Vallim, Nam Che, Michael Wierer, Peter A Edwards

Circulation· May 2021

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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Marta Pradas-Juni, Nils R Hansmeier, Jenny C Link, Elena Schmidt, Bjørk Ditlev Larsen, Peter A Edwards

Nat Commun· January 2020

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Intracellular Localization of Endogenous Mouse ABCG1 Is Mimicked by Both ABCG1-L550 and ABCG1-P550-Brief Report.
Elizabeth J Tarling, Peter A Edwards

Arterioscler Thromb Vasc Biol· July 2016

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Focal middle cerebral artery ischemia in rats via a transfemoral approach using a custom designed microwire.
Afshin A Divani, Ricky Chow, Homayoun Sadeghi-Bazargani, Amanda J Murphy, Jessica A Nordberg, Peter A Edwards

J Neurointerv Surg· June 2016

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MAFG is a transcriptional repressor of bile acid synthesis and metabolism.
Thomas Q de Aguiar Vallim, Elizabeth J Tarling, Hannah Ahn, Lee R Hagey, Casey E Romanoski, Peter A Edwards

Cell Metab· February 2015

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Upregulation of endogenous farnesyl diphosphate synthase overcomes the inhibitory effect of bisphosphonate on protein prenylation in Hela cells.
Subhajit Das, Peter A Edwards, Julie C Crockett, Michael J Rogers

Biochim Biophys Acta· April 2014

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LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition.
Xin Rong, Carolyn J Albert, Cynthia Hong, Mark A Duerr, Brian T Chamberlain, Peter A Edwards

Cell Metab· November 2013

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Role of ABC transporters in lipid transport and human disease.
Elizabeth J Tarling, Thomas Q de Aguiar Vallim, Peter A Edwards

Trends Endocrinol Metab· July 2013

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MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.
Thomas Q de Aguiar Vallim, Elizabeth J Tarling, Tammy Kim, Mete Civelek, Ángel Baldán, Peter A Edwards

Circ Res· June 2013

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Pleiotropic roles of bile acids in metabolism.
Thomas Q de Aguiar Vallim, Elizabeth J Tarling, Peter A Edwards

Cell Metab· May 2013

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Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
Abdoulaye Sene, Aslam A Khan, Douglas Cox, Rei E I Nakamura, Andrea Santeford, Peter A Edwards

Cell Metab· April 2013

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Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.
Brian J Bennett, Thomas Q de Aguiar Vallim, Zeneng Wang, Diana M Shih, Yonghong Meng, Peter A Edwards

Cell Metab· January 2013

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Dancing with the sterols: critical roles for ABCG1, ABCA1, miRNAs, and nuclear and cell surface receptors in controlling cellular sterol homeostasis.
Elizabeth J Tarling, Peter A Edwards

Biochim Biophys Acta· March 2012

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Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.
Yanqiao Zhang, Xuemei Ge, Lydia A Heemstra, Wei-Dong Chen, Jiesi Xu, Peter A Edwards

Mol Endocrinol· February 2012

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ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter.
Elizabeth J Tarling, Peter A Edwards

Proc Natl Acad Sci U S A· December 2011

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Hepatic hepatocyte nuclear factor 4α is essential for maintaining triglyceride and cholesterol homeostasis.
Liya Yin, Huiyan Ma, Xuemei Ge, Peter A Edwards, Yanqiao Zhang

Arterioscler Thromb Vasc Biol· February 2011

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Regulation of ABCG1 expression in human keratinocytes and murine epidermis.
Yan J Jiang, Biao Lu, Elizabeth J Tarling, Peggy Kim, M-Q Man, Peter A Edwards

J Lipid Res· November 2010

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Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1.
Hansook Kim Chong, Aniello M Infante, Young-Kyo Seo, Tae-Il Jeon, Yanqiao Zhang, Peter A Edwards

Nucleic Acids Res· October 2010

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Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity.
Florence Ying Lee, Thomas Quad de Aguiar Vallim, Hansook Kim Chong, Yanqiao Zhang, Yaping Liu, Peter A Edwards

Mol Endocrinol· August 2010

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Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis.
Elizabeth J Tarling, Dragana D Bojanic, Rajendra K Tangirala, Xuping Wang, Anita Lovgren-Sandblom, Peter A Edwards

Arterioscler Thromb Vasc Biol· June 2010

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Differential expression and function of ABCG1 and ABCG4 during development and aging.
Dragana D Bojanic, Paul T Tarr, Greg D Gale, Desmond J Smith, Dean Bok, Peter A Edwards

J Lipid Res· January 2010

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Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Yanqiao Zhang, Liya Yin, Jody Anderson, Huiyan Ma, Frank J Gonzalez, Peter A Edwards

J Biol Chem· January 2010

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Bile acids have the gall to function as hormones.
Thomas Quad de Aguiar Vallim, Peter A Edwards

Cell Metab· September 2009

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Emerging new paradigms for ABCG transporters.
Paul T Tarr, Elizabeth J Tarling, Dragana D Bojanic, Peter A Edwards, Angel Baldán

Biochim Biophys Acta· July 2009

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