Publications by authors named "Peter A Sims"

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Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity.
Alexander Y Yang, Julia Davis-Porada, Daniel H Paik, Alex B George, Brea H Brown, Peter A Sims

J Exp Med· January 2026

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Tissue signatures of human macrophages during homeostasis and activation.
Daniel P Caron, William L Specht, Siddhi Nargund, David Chen, Steven B Wells, Peter A Sims

J Immunol· December 2025

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HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptake.
Verena Haage, John F Tuddenham, Alex Bautista, Frankie Garcia G, Charles C White, Peter A Sims

Brain Behav Immun· October 2025

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Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age.
Steven B Wells, Daniel B Rainbow, Michal Mark, Peter A Szabo, Can Ergen, Peter A Sims

Nat Immunol· September 2025

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Convection-enhanced delivery of dexamethasone in glioma suppresses myeloid inflammation while avoiding systemic toxicities.
Nathaniel W Rolfe, Nicholas B Dadario, Liang Lei, Damian E Teasley, Misha Amini, Peter A Sims

bioRxiv· September 2025

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The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra.
Maxwell Ma, Fahad Paryani, Kelly Jakubiak, Shengnan Xia, Susumu Antoku, Peter A Sims

Nat Commun· August 2025

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ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets.
Ye Zheng, Daniel P Caron, Ju Yeong Kim, Seong-Hwan Jun, Yuan Tian, Peter A Sims

Nat Commun· July 2025

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Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord.
John F Tuddenham, Masashi Fujita, Emily Lee, Nivedita Nimmagadda, Anthony Khairallah, Peter A Sims

Acta Neuropathol· July 2025

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Tissue signatures of human macrophages during homeostasis and activation.
Daniel P Caron, William L Specht, David Chen, Steven B Wells, Peter A Szabo, Peter A Sims

bioRxiv· May 2025

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LIN28B-mediated PI3K/AKT pathway activation promotes metastasis in colorectal cancer models.
Alice E Shin, Kensuke Sugiura, Secunda W Kariuki, David A Cohen, Samuel P Flashner, Peter A Sims

J Clin Invest· April 2025

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Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition.
Alexander R Goldberg, Athanassios Dovas, Daniela Torres, Brianna Pereira, Ashwin Viswanathan, Peter A Sims

Neuron· March 2025

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Scalable co-sequencing of RNA and DNA from individual nuclei.
Timothy R Olsen, Pranay Talla, Romella K Sagatelian, Julia Furnari, Jeffrey N Bruce, Peter A Sims

Nat Methods· March 2025

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Decoding neuronal wiring by joint inference of cell identity and synaptic connectivity.
Himanshu Pawankumar Gupta, Anthony W Azevedo, Yu-C-Hieh David Chen, Kristi Xing, Peter A Sims

bioRxiv· March 2025

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A factor-based analysis of individual human microglia uncovers regulators of an Alzheimer-related transcriptional signature.
Victoria S Marshe, John F Tuddenham, Kevin Chen, Rebecca Chiu, Verena C Haage, Peter A Sims

bioRxiv· March 2025

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Transcriptional control of T cell tissue adaptation and effector function in infants and adults.
Peter A Szabo, Hanna M Levitin, Thomas J Connors, David Chen, Jenny Jin, Peter A Sims

bioRxiv· February 2025

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Multimodal hierarchical classification of CITE-seq data delineates immune cell states across lineages and tissues.
Daniel P Caron, William L Specht, David Chen, Steven B Wells, Peter A Szabo, Peter A Sims

Cell Rep Methods· January 2025

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A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states.
John F Tuddenham, Mariko Taga, Verena Haage, Victoria S Marshe, Tina Roostaei, Peter A Sims

Nat Neurosci· December 2024

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Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues.
Julia Davis-Porada, Alex B George, Nora Lam, Daniel P Caron, Joshua I Gray, Peter A Sims

Immunity· December 2024

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Resistance to spindle inhibitors in glioblastoma depends on STAT3 and therapy induced senescence.
Natanael Zarco, Athanassios Dovas, Virginea de Araujo Farias, Naveen K H Nagaiah, Ashley Haddock, Peter A Sims

iScience· December 2024

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PRRX1 Has Functional Roles in Pancreatic Acinar to Ductal Metaplasia and Carcinogenesis.
Noriyuki Nishiwaki, Kensuke Sugiura, Kensuke Suzuki, Alina L Li, Constanza Tapia Contreras, Peter A Sims

Cell Mol Gastroenterol Hepatol· December 2024

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FRA1 controls acinar cell plasticity during murine Kras-induced pancreatic acinar to ductal metaplasia.
Alina L Li, Kensuke Sugiura, Noriyuki Nishiwaki, Kensuke Suzuki, Dorsay Sadeghian, Peter A Sims

Dev Cell· November 2024

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Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord.
John F Tuddenham, Masashi Fujita, Anthony Khairallah, Claire Harbison, Xena E Flowers, Peter A Sims

bioRxiv· November 2024

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A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
Matei A Banu, Athanassios Dovas, Michael G Argenziano, Wenting Zhao, Colin P Sperring, Peter A Sims

EMBO J· October 2024

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HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures .
Verena Haage, John F Tuddenham, Alex Bautista, Charles C White, Frankie Garcia, Peter A Sims

bioRxiv· October 2024

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MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, microglia phenotype, and immune checkpoint blockade efficacy.
Kwang-Soo Kim, Junyi Zhang, Víctor A Arrieta, Crismita Dmello, Elena Grabis, Peter A Sims

bioRxiv· September 2024

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