Publications by authors named "Peter Bradding"

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Does Adherence to Inhaled Corticosteroids/Long-Acting β-Agonists Matter in Patients With Severe Asthma Receiving Biologic Therapies?
Peter Bradding

J Allergy Clin Immunol Pract· October 2025

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Assessment of an Oral Corticosteroid Withdrawal Pathway for Severe Asthma Patients Receiving Biologic Therapies.
Hnin W W Aung, Richard J Russell, Claire E Boddy, Kumaran Balasundaram, Eleanor Hampson, Peter Bradding

J Allergy Clin Immunol Pract· July 2025

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Urinary thromboxane and isoprostane levels are elevated in symptom-high T2-biomarker-low severe asthma.
Matthew Chad Eastwood, John Busby, Johan Kolmert, Javier Zurita, Sven-Erik Dahlén, Peter Bradding

ERJ Open Res· July 2025

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TGFβ1 generates a pro-fibrotic proteome in human lung parenchyma that is sensitive to pharmacological intervention.
Colleen B Maxwell, Panayiota Stylianou, Hilary Marshall, Alfie J Hall, Paulene A Quinn, Peter Bradding

Eur J Pharmacol· June 2025

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The Role of WNT5a and TGF-β1 in Airway Remodelling and Severe Asthma.
Tariq Daud, Sheree Roberts, Nazanin Zounemat Kermani, Matthew Richardson, Liam G Heaney, Peter Bradding

Allergy· April 2025

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Airway tryptase levels inform the lack of clinical efficacy of the tryptase inhibitor MTPS9579A in asthma.
Horace Rhee, Lindsay M Henderson, Rebecca N Bauer, Kit Wong, Tracy L Staton, Peter Bradding

Allergy· November 2024

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Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic Omalizumab in Severe Asthma in Adults: Results of the SoMOSA Study.
Ratko Djukanović, Paul Brinkman, Johan Kolmert, Cristina Gomez, James Schofield, Peter Bradding

Am J Respir Crit Care Med· August 2024

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The effects of inhaled corticosteroids on healthy airways.
Emanuele Marchi, Timothy S C Hinks, Matthew Richardson, Latifa Khalfaoui, Fiona A Symon, Peter Bradding

Allergy· July 2024

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Assessing Inhaled Corticosteroid Adherence and Responsiveness in Severe Asthma Using Beclometasone Dipropionate/Formoterol NEXThaler Dose-Counting and Nitric Oxide Monitoring.
Hnin W W Aung, Claire E Boddy, Eleanor Hampson, Mark Bell, Lauren A Parnell, Peter Bradding

J Allergy Clin Immunol Pract· June 2024

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Airway hyperresponsiveness in asthma: The role of the epithelium.
Peter Bradding, Celeste Porsbjerg, Andréanne Côté, Sven-Erik Dahlén, Teal S Hallstrand

J Allergy Clin Immunol· May 2024

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Enabling Adults With Severe Asthma to Exercise: A Qualitative Examination of the Challenges for Patients and Health Care Professionals.
Lindsay D Apps, Stacey Chantrell, Sally Majd, Elizabeth Eglinton, Sally J Singh, Peter Bradding

J Allergy Clin Immunol Pract· November 2023

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Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control.
Xue Zeng, Jing Qing, Chi-Ming Li, Jiamiao Lu, Tracy Yamawaki, Peter Bradding

J Allergy Clin Immunol· October 2023

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Identification of redundancy between human FcεRIβ and MS4A6A proteins points toward additional complex mechanisms for FcεRI trafficking and signaling.
Katie Bitting, Barry Hedgespeth, Lauren C Ehrhardt-Humbert, Greer K Arthur, Alicia G Schubert, Peter Bradding

Allergy· May 2023

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A Randomized Trial of a Composite T2-Biomarker Strategy Adjusting Corticosteroid Treatment in Severe Asthma: A Post Hoc Analysis by Sex.
Matthew C Eastwood, John Busby, David J Jackson, Ian D Pavord, Catherine E Hanratty, Peter Bradding

J Allergy Clin Immunol Pract· April 2023

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Relationship between inflammatory status and microbial composition in severe asthma and during exacerbation.
Sarah Diver, Koirobi Haldar, Pamela Jane McDowell, John Busby, Vijay Mistry, Peter Bradding

Allergy· November 2022

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Corticosteroid Responsiveness Following Mepolizumab in Severe Eosinophilic Asthma-A Randomized, Placebo-Controlled Crossover Trial (MAPLE).
Freda Yang, John Busby, Liam G Heaney, Ian D Pavord, Chris E Brightling, Peter Bradding

J Allergy Clin Immunol Pract· November 2022

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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma.
Latifa Khalfaoui, Fiona A Symon, Simon Couillard, Beverley Hargadon, Rekha Chaudhuri, Peter Bradding

Allergy· October 2022

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Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes.
P Jane McDowell, John Busby, Catherine E Hanratty, Ratko Djukanovic, Ashley Woodcock, Peter Bradding

Am J Respir Crit Care Med· September 2022

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Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma.
John Busby, John G Matthews, Rekha Chaudhuri, Ian D Pavord, Timothy C Hardman, Peter Bradding

Eur Respir J· April 2022

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Mechanisms of Mast Cell Activation in Severe Asthma: Beyond IgE.
Peter Bradding

Am J Respir Crit Care Med· February 2022

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Human Lung Mast Cells Impair Corticosteroid Responsiveness in Human Airway Smooth Muscle Cells.
Abdulrahman Alzahrani, Jameel Hakeem, Michael Biddle, Fahad Alhadian, Aamir Hussain, Peter Bradding

Front Allergy· December 2021

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Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma.
Simon Couillard, Rahul Shrimanker, Rekha Chaudhuri, Adel H Mansur, Lorcan P McGarvey, Peter Bradding

Am J Respir Crit Care Med· September 2021

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Mast-Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis.
Roya Babaei-Jadidi, Arundhati Dongre, Suzanne Miller, Marcos Castellanos Uribe, Ian D Stewart, Peter Bradding

Am J Respir Crit Care Med· August 2021

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Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
Giuseppe Campiani, Caterina Cavella, Jeremy D Osko, Margherita Brindisi, Nicola Relitti, Peter Bradding

J Med Chem· July 2021

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Pro: Access to advanced therapies for severe asthma should be restricted to patients with satisfactory adherence to maintenance treatment.
Anna C Murphy, Claire Boddy, Peter Bradding

Breathe (Sheff)· June 2021

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