Publications by authors named "Peter Burch"

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Characterization of a humanized mouse model of Duchenne muscular dystrophy to support the development of genetic medicines.
Kara Braunreiter, Amber Kempton, Maria Katherine Mejia-Guerra, Andrew Murray, Stephen Baine, Peter Burch

Dis Model Mech· October 2025

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Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid.
Isabel V L Wilkinson, Kelly J Perkins, Hannah Dugdale, Lee Moir, Aini Vuorinen, Peter Burch

Angew Chem Int Ed Engl· February 2020

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A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys.
Michael St Andre, Mark Johnson, Prashant N Bansal, Jeremy Wellen, Andrew Robertson, Peter M Burch

Skelet Muscle· November 2017

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Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance.
Peter M Burch, Warren E Glaab, Daniel J Holder, Jonathan A Phillips, John-Michael Sauer

Toxicol Sci· March 2017

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Reduced serum myostatin concentrations associated with genetic muscle disease progression.
Peter M Burch, Oksana Pogoryelova, Joe Palandra, Richard Goldstein, Donald Bennett

J Neurol· March 2017

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Evaluation of the Relative Performance of Drug-Induced Skeletal Muscle Injury Biomarkers in Rats.
Peter M Burch, David Greg Hall, Elizabeth G Walker, William Bracken, Richard Giovanelli

Toxicol Sci· March 2016

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Muscle-Derived Proteins as Serum Biomarkers for Monitoring Disease Progression in Three Forms of Muscular Dystrophy.
Peter M Burch, Oksana Pogoryelova, Richard Goldstein, Donald Bennett, Michela Guglieri

J Neuromuscul Dis· September 2015

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Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells.
Priya Ranjan, Vikas Anathy, Peter M Burch, Kelly Weirather, J David Lambeth

Antioxid Redox Signal· January 2007

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SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth.
Mara Fornaro, Peter M Burch, Wentian Yang, Lei Zhang, Claire E Hamilton

J Cell Biol· October 2006

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Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling.
Per Uhlén, Peter M Burch, Christina Ivins Zito, Manuel Estrada, Barbara E Ehrlich

Proc Natl Acad Sci U S A· February 2006

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Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species.
Peter M Burch, Nicholas H Heintz

Antioxid Redox Signal· September 2005

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An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry.
Peter M Burch, Ziqiang Yuan, Anne Loonen, Nicholas H Heintz

Mol Cell Biol· June 2004

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Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide.
Ziqiang Yuan, Harriet Schellekens, Loraine Warner, Yvonne Janssen-Heininger, Peter Burch

Am J Respir Cell Mol Biol· June 2003

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