Publications by authors named "Peter Chua"

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Correction to "Total Synthesis of (-)-Sarain A".
Michael H Becker, Peter Chua, Robert Downham, Christopher J Douglas, Neil K Garg

J Am Chem Soc· April 2018

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Synthesis and SAR of inhibitors of protein kinase CK2: novel tricyclic quinoline analogs.
Mustapha Haddach, Fabrice Pierre, Collin F Regan, Cosmin Borsan, Jerome Michaux, Peter C Chua

Bioorg Med Chem Lett· January 2012

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Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer.
Fabrice Pierre, Peter C Chua, Sean E O'Brien, Adam Siddiqui-Jain, Pauline Bourbon

Mol Cell Biochem· October 2011

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Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.
Fabrice Pierre, Peter C Chua, Sean E O'Brien, Adam Siddiqui-Jain, Pauline Bourbon

J Med Chem· January 2011

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CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy.
Adam Siddiqui-Jain, Denis Drygin, Nicole Streiner, Peter Chua, Fabrice Pierre

Cancer Res· December 2010

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The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity.
Tony Siu, Yiwei Li, Johnny Nagasawa, Jun Liang, Lida Tehrani, Peter Chua

Bioorg Med Chem Lett· July 2008

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Total synthesis of (+)-sarain A.
Michael H Becker, Peter Chua, Robert Downham, Christopher J Douglas, Neil K Garg

J Am Chem Soc· October 2007

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Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.
Peter C Chua, Johnny Y Nagasawa, Leo S Bleicher, Benito Munoz, Edwin J Schweiger

Bioorg Med Chem Lett· October 2005

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Pyrimidine methyl anilines: selective potentiators for the metabotropic glutamate 2 receptor.
Essa Hu, Peter C Chua, Lida Tehrani, Johnny Y Nagasawa, Anthony B Pinkerton

Bioorg Med Chem Lett· October 2004

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