Publications by authors named "Peter Doig"

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Gender trends in dentistry: Dental faculty and academic leadership.
Aram Kim, Nour Karra, Crystal Song, Pamela J Linder, Francesca Bonino, Peter Doig

J Dent Educ· January 2024

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Antibacterial Spiropyrimidinetriones with N-Linked Azole Substituents on a Benzisoxazole Scaffold Targeting DNA Gyrase.
Gregory S Basarab, Peter Doig, Charles J Eyermann, Vincent Galullo, Gunther Kern

J Med Chem· October 2020

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Insight into the Therapeutic Selectivity of the Irreversible EGFR Tyrosine Kinase Inhibitor Osimertinib through Enzyme Kinetic Studies.
Xiang Zhai, Richard A Ward, Peter Doig, Argyrides Argyrou

Biochemistry· April 2020

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Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.
Jayashree Chadchankar, Victoria Korboukh, Leslie C Conway, Heike J Wobst, Chandler A Walker, Peter Doig

PLoS One· March 2020

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Phosphorylation of Glutamine Synthetase on Threonine 301 Contributes to Its Inactivation During Epilepsy.
Deborah Huyghe, Andrew R Denninger, Caroline M Voss, Pernille Frank, Ning Gao, Peter Doig

Front Mol Neurosci· May 2019

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Mouse Red Blood Cell-Mediated Rare Xenobiotic Phosphorylation of a Drug Molecule Not Intended to Be a Kinase Substrate.
Chungang Gu, Shenghua Wen, Peter Doig, Eric Gangl, Xiaolan Zheng

Drug Metab Dispos· December 2017

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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Alexis I Cocozaki, Roger B Altman, Jian Huang, Ed T Buurman, Steven L Kazmirski, Peter Doig

Proc Natl Acad Sci U S A· July 2016

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Corrigendum: Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Gregory S Basarab, Gunther H Kern, John McNulty, John P Mueller, Kenneth Lawrence, Peter Doig

Sci Rep· September 2015

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Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914.
Gunther Kern, Tiffany Palmer, David E Ehmann, Adam B Shapiro, Beth Andrews, Peter Doig

J Biol Chem· August 2015

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Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914).
Gregory S Basarab, Peter Doig, Vincent Galullo, Gunther Kern, Amy Kimzey

J Med Chem· August 2015

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Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Gregory S Basarab, Gunther H Kern, John McNulty, John P Mueller, Kenneth Lawrence, Peter Doig

Sci Rep· July 2015

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Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain.
Ning Gao, Sarah M McLeod, Laurel Hajec, Nelson B Olivier, Sushmita D Lahiri, Peter Doig

Protein Expr Purif· December 2014

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Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Peter Doig, P Ann Boriack-Sjodin, Jacques Dumas, Jun Hu, Kenji Itoh

Bioorg Med Chem· November 2014

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Novel DNA gyrase inhibiting spiropyrimidinetriones with a benzisoxazole scaffold: SAR and in vivo characterization.
Gregory S Basarab, Patrick Brassil, Peter Doig, Vincent Galullo, Howard B Haimes

J Med Chem· November 2014

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Developing a national oral health strategy.
Peter Doig

J Can Dent Assoc· February 2014

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CDA advocacy: making a difference in oral health care.
Peter Doig

J Can Dent Assoc· February 2014

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Response from Dr. Peter Doig.
Peter Doig

J Can Dent Assoc· February 2014

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Screening-based discovery of the first novel ATP competitive inhibitors of the Staphylococcus aureus essential enzyme UMP kinase.
Peter Doig, Elise Gorseth, Tory Nash, Arthur Patten, Ning Gao

Biochem Biophys Res Commun· July 2013

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In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound.
Thomas A Keating, Joseph V Newman, Nelson B Olivier, Linda G Otterson, Beth Andrews, Peter Doig

ACS Chem Biol· November 2012

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An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode.
Nicholas A Larsen, Tory J Nash, Marshall Morningstar, Adam B Shapiro, Camil Joubran, Peter Doig

Biochem J· September 2012

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Bacterial DNA replication enzymes as targets for antibacterial drug discovery.
Gautam Sanyal, Peter Doig

Expert Opin Drug Discov· April 2012

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Exploring 8-benzyl pteridine-6,7-diones as inhibitors of glutamate racemase (MurI) in gram-positive bacteria.
Gloria A Breault, Janelle Comita-Prevoir, Charles J Eyermann, Bolin Geng, Randy Petrichko, Peter Doig

Bioorg Med Chem Lett· December 2008

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Exploring 9-benzyl purines as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria.
Bolin Geng, Gloria Breault, Janelle Comita-Prevoir, Randy Petrichko, Charles Eyermann, Peter Doig

Bioorg Med Chem Lett· August 2008

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