Publications by authors named "Peter Dove"

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Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine.
Subhash C Annedi, Shawn P Maddaford, Jailall Ramnauth, Paul Renton, Taras Rybak, Peter Dove

Eur J Med Chem· September 2012

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Novel, druglike 1,7-disubstituted 2,3,4,5-tetrahydro-1H-benzo[b]azepine-based selective inhibitors of human neuronal nitric oxide synthase (nNOS).
Subhash C Annedi, Jailall Ramnauth, Michele Cossette, Shawn P Maddaford, Peter Dove

Bioorg Med Chem Lett· April 2012

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1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors: lead optimization studies resulting in the identification of N-(1-(2-(methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a preclinical development candidate.
Jailall Ramnauth, Paul Renton, Peter Dove, Subhash C Annedi, Joanne Speed

J Med Chem· March 2012

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Discovery of cis-N-(1-(4-(methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: a 1,6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxide synthase (nNOS) without any cardiovascular liabilities.
Subhash C Annedi, Jailall Ramnauth, Shawn P Maddaford, Paul Renton, Suman Rakhit, Peter Dove

J Med Chem· January 2012

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Slow-dissociation and slow-recombination assumptions in nonequilibrium capillary electrophoresis of equilibrium mixtures.
Svetlana M Krylova, Peter M Dove, Mirzo Kanoatov, Sergey N Krylov

Anal Chem· October 2011

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Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.
Jailall Ramnauth, Joanne Speed, Shawn P Maddaford, Peter Dove, Subhash C Annedi

J Med Chem· August 2011

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Synthesis and protection of aryl sulfates using the 2,2,2-trichloroethyl moiety.
Yong Liu, I-Feh Felicia Lien, Scott Ruttgaizer, Peter Dove, Scott D Taylor

Org Lett· January 2004

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