Publications by authors named "Peter Florian"

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Combined TNF-α and OX40L targeting as a new treatment option for hidradenitis suppurativa.
Thomas Leeuw, Deimantė Šimaitė, Karen Heyninck, Clement Levin, Sigrid Cornelis, Peter Florian

J Allergy Clin Immunol Glob· August 2025

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Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof-of-concept study.
Chad W Schmiedt, Bianca N Lourenço, Lauren E Markovic, Meghan Lancaster, Sanjeev Gumber, Peter Florian

Animal Model Exp Med· May 2025

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Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Alexander Vugler, James O'connell, Mai Anh Nguyen, Dietmar Weitz, Thomas Leeuw, Peter Florian

Front Pharmacol· October 2024

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Immunomodulatory and clinical effects of receptor-interacting protein kinase 1 (RIPK1) inhibitor eclitasertib (SAR443122) in patients with severe COVID-19: a phase 1b, randomized, double-blinded, placebo-controlled study.
Pierre-Francois Clot, Christine Farenc, Benjamin T Suratt, Tillmann Krahnke, Agnes Tardat, Peter Florian

Respir Res· February 2024

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Platinum-DNA Origami Hybrid Structures in Concentrated Hydrogen Peroxide.
Mariana Alarcón-Correa, Luzia Kilwing, Florian Peter, Tim Liedl, Peer Fischer

Chemphyschem· November 2023

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Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.
Elizabeth S Hickford, James O'Connell, Alison Maloney, Peter Florian, Geoffrey I Johnston

Bioanalysis· March 2023

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An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Alexander Vugler, James O'Connell, Mai Anh Nguyen, Dietmar Weitz, Thomas Leeuw, Peter Florian

Front Pharmacol· November 2022

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Light- and magnetically actuated FePt microswimmers.
Vincent Mauricio Kadiri, Jan-Philipp Günther, Sai Nikhilesh Kottapalli, Rahul Goyal, Florian Peter

Eur Phys J E Soft Matter· June 2021

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Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy.
Peter Florian, Klaus R Flechsenhar, Eckart Bartnik, Danping Ding-Pfennigdorff, Matthias Herrmann

Exp Dermatol· January 2020

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Novel inhibitor ZED3197 as potential drug candidate in anticoagulation targeting coagulation FXIIIa (F13a).
Ralf Pasternack, Christian Büchold, Robert Jähnig, Christiane Pelzer, Michael Sommer, Peter Florian

J Thromb Haemost· January 2020

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LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.
Cornelia Pipper, Natalie Bordag, Bernadette Reiter, Kyriakos Economides, Peter Florian

J Lipid Res· April 2019

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Anti-GPVI Fab SAR264565 effectively blocks GPVI function in ex vivo human platelets under arterial shear in a perfusion chamber.
Peter Florian, Peter Wonerow, Sebastian Harder, Karina Kuczka, Michel Dubar

Eur J Clin Pharmacol· August 2017

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visualization of osteoarthritic hypertrophic lesions.
Hai-Yu Hu, Ngee-Han Lim, Hans-Paul Juretschke, Danping Ding-Pfennigdorff, Peter Florian

Chem Sci· November 2015

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5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor.
Jerome Meneyrol, Markus Follmann, Gilbert Lassalle, Volkmar Wehner, Guillaume Barre, Peter Florian

J Med Chem· December 2013

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Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone.
Gernot Zech, Gerhard Hessler, Andreas Evers, Tilo Weiss, Peter Florian

J Med Chem· October 2012

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Selective non-lipid modulator of LPA5 activity in human platelets.
Detlef H Kozian, Andreas Evers, Peter Florian, Peter Wonerow, Sabrina Joho

Bioorg Med Chem Lett· August 2012

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Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.
Frank Heller, Peter Florian, Christian Bojarski, Jan Richter, Melanie Christ

Gastroenterology· August 2005

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Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells.
Salah Amasheh, Thomas Schmidt, Michaela Mahn, Peter Florian, Joachim Mankertz

Cell Tissue Res· July 2005

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Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure.
John M Russo, Peter Florian, Le Shen, W Vallen Graham, Maria S Tretiakova

Gastroenterology· April 2005

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Cytokine-dependent transcriptional down-regulation of epithelial sodium channel in ulcerative colitis.
Salah Amasheh, Christian Barmeyer, Corinna Swanette Koch, Shida Tavalali, Joachim Mankertz, Peter Florian

Gastroenterology· June 2004

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The specific fates of tight junction proteins in apoptotic epithelial cells.
Christian Bojarski, Jörg Weiske, Torsten Schöneberg, Werner Schröder, Joachim Mankertz, Peter Florian

J Cell Sci· April 2004

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Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage.
Joachim Mankertz, Jörg Stefan Waller, Bernd Hillenbrand, Shida Tavalali, Peter Florian

Biochem Biophys Res Commun· November 2002

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Supernatants of HIV-infected immune cells affect the barrier function of human HT-29/B6 intestinal epithelial cells.
Heinz Schmitz, Katharina Rokos, Peter Florian, Alfred H Gitter, Michael Fromm

AIDS· May 2002

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