Publications by authors named "Gernot Zech"

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Trivalent siRNA-Conjugates with Guanosine as ASGPR-Binder Show Potent Knock-Down In Vivo.
Armin Hofmeister, Kerstin Jahn-Hofmann, Bodo Brunner, Mike Helms, Christiane Metz-Weidmann, Gernot Zech

J Med Chem· March 2025

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Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Sven Ruf, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, Mahanandeesha S Hallur, Shilpa Rani, Gernot Zech, Joerg Czech

Sci Rep· September 2022

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Novel Inhibitors of Nicotinamide--Methyltransferase for the Treatment of Metabolic Disorders.
Aimo Kannt, Sridharan Rajagopal, Mahanandeesha S Hallur, Indu Swamy, Rajendra Kristam, Joerg Czech, Gernot Zech

Molecules· February 2021

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Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis.
Anurag Mishra, Tamara R Castañeda, Erik Bader, Bettina Elshorst, Sheila Cummings, Gernot Zech

Adv Sci (Weinh)· December 2020

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N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Christophe Boldron, Angélina Besse, Marie-Françoise Bordes, Stéphanie Tissandié, Xavier Yvon, Gernot Zech

J Med Chem· September 2014

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Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone.
Gernot Zech, Gerhard Hessler, Andreas Evers, Tilo Weiss, Peter Florian, Jörg Czech, Werngard Czechtizky

J Med Chem· October 2012

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Synthesis of a polymer-bound galactosylamine and its application as an immobilized chiral auxiliary in stereoselective syntheses of piperidine and amino acid derivatives.
Gernot Zech, Horst Kunz

Chemistry· September 2004

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Stereoselective solid-phase synthesis of chiral piperidine derivatives by using an immobilized galactose auxiliary.
Gernot Zech, Horst Kunz

Angew Chem Int Ed Engl· February 2003

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Nucleophilically assisted and cationic ring-opening polymerization of tin-bridged [1]ferrocenophanes.
Thomas Baumgartner, Frieder Jäkle, Ron Rulkens, Gernot Zech, Alan J Lough

J Am Chem Soc· August 2002

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Dipolar recoupling in NOESY-type 1H-1H NMR experiments under HRMAS conditions.
Karena Thieme, Gernot Zech, Horst Kunz, Hans Wolfgang Spiess, Ingo Schnell

Org Lett· May 2002

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