Publications by authors named "Peter Friedhoff"

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Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors.
Yannicka Mardenborough, Romano M van Genderen, Charlie Laffeber, Kelly D A de Koning, Peter Friedhoff

J Biol Chem· November 2025

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Secondary 3-Chloropiperidines: Powerful Alkylating Agents.
Mats Georg, Lina Alexandra Laping, Veronica Billo, Barbara Gatto, Peter Friedhoff

ChemistryOpen· June 2024

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MutL Activates UvrD by Interaction Between the MutL C-terminal Domain and the UvrD 2B Domain.
Olha Storozhuk, Susanne R Bruekner, Ankon Paul, Joyce H G Lebbink, Titia K Sixma, Peter Friedhoff

J Mol Biol· June 2024

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Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA-Protein Complexes Using Mismatch Repair Protein MutS as a Model.
Mayya V Monakhova, Elena A Kubareva, Kirill K Kolesnikov, Viktor A Anashkin, Egor M Kosaretskiy, Peter Friedhoff

Molecules· April 2022

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Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair.
Alessandro Borsellini, Vladislav Kunetsky, Peter Friedhoff, Meindert H Lamers

Nat Struct Mol Biol· January 2022

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The selection process of licensing a DNA mismatch for repair.
Rafael Fernandez-Leiro, Doreth Bhairosing-Kok, Vladislav Kunetsky, Charlie Laffeber, Herrie H Winterwerp, Peter Friedhoff

Nat Struct Mol Biol· April 2021

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Probing the DNA-binding center of the MutL protein from the Escherichia coli mismatch repair system via crosslinking and Förster resonance energy transfer.
Maya Monakhova, Alexandra Ryazanova, Vladislav Kunetsky, Pingping Li, Evgeniy Shilkin, Peter Friedhoff

Biochimie· December 2020

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The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair.
Yannicka S N Mardenborough, Katerina Nitsenko, Charlie Laffeber, Camille Duboc, Enes Sahin, Peter Friedhoff

Nucleic Acids Res· December 2019

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Mechanism and Regulation of Co-transcriptional mRNP Assembly and Nuclear mRNA Export.
Wolfgang Wende, Peter Friedhoff, Katja Sträßer

Adv Exp Med Biol· December 2019

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Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3.
Tim Schneider, Lee-Hsueh Hung, Masood Aziz, Anna Wilmen, Stephanie Thaum, Peter Friedhoff

Nat Commun· May 2019

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Use of Single-Cysteine Variants for Trapping Transient States in DNA Mismatch Repair.
Peter Friedhoff, Laura Manelyte, Luis Giron-Monzon, Ines Winkler, Flora S Groothuizen

Methods Enzymol· April 2018

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Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.
Nicolaas Hermans, Charlie Laffeber, Michele Cristovão, Mariela Artola-Borán, Yannicka Mardenborough, Peter Friedhoff

Nucleic Acids Res· August 2016

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Protein-protein interactions in DNA mismatch repair.
Peter Friedhoff, Pingping Li, Julia Gotthardt

DNA Repair (Amst)· February 2016

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Editorial: Alfred Pingoud (1945-2015).
Albert Jeltsch, Wolfgang Wende, Peter Friedhoff, Barry L Stoddard

Nucleic Acids Res· September 2015

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MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.
Flora S Groothuizen, Ines Winkler, Michele Cristóvão, Alexander Fish, Herrie H K Winterwerp, Peter Friedhoff

Elife· July 2015

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Is thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?
Svetlana A Perevozchikova, Roman M Trikin, Roger J Heinze, Elena A Romanova, Tatiana S Oretskaya, Peter Friedhoff

PLoS One· May 2015

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Chromatographic isolation of the functionally active MutS protein covalently linked to deoxyribonucleic acid.
Mayya Monakhova, Alexandra Ryazanova, Andreas Hentschel, Mikhail Viryasov, Tatiana Oretskaya, Peter Friedhoff

J Chromatogr A· April 2015

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Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation.
Flora S Groothuizen, Alexander Fish, Maxim V Petoukhov, Annet Reumer, Laura Manelyte, Peter Friedhoff

Nucleic Acids Res· September 2013

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Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats.
Lilia Gabsalilow, Benno Schierling, Peter Friedhoff, Alfred Pingoud, Wolfgang Wende

Nucleic Acids Res· April 2013

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Single-molecule multiparameter fluorescence spectroscopy reveals directional MutS binding to mismatched bases in DNA.
Michele Cristóvão, Evangelos Sisamakis, Manju M Hingorani, Andreas D Marx, Caroline P Jung, Peter Friedhoff

Nucleic Acids Res· July 2012

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Covalently trapping MutS on DNA to study DNA mismatch recognition and signaling.
Roger J Heinze, Svetlana Sekerina, Ines Winkler, Christian Biertümpfel, Tatiana S Oretskaya, Peter Friedhoff

Mol Biosyst· July 2012

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Chemical rescue of active site mutants of S. pneumoniae surface endonuclease EndA and other nucleases of the HNH family by imidazole.
Marika Midon, Oleg Gimadutdinow, Gregor Meiss, Peter Friedhoff, Alfred Pingoud

Chembiochem· March 2012

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Crosslinking of (cytosine-5)-DNA methyltransferase SsoII and its complexes with specific DNA duplexes provides an insight into their structures.
Alexandra Yurievna Ryazanova, Ines Winkler, Peter Friedhoff, Mikhail Borisovich Viryasov, Tatiana Semenovna Oretskaya

Nucleosides Nucleotides Nucleic Acids· December 2011

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Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS.
Maria Chiara Monti, Serge X Cohen, Alexander Fish, Herrie H K Winterwerp, Arjan Barendregt, Peter Friedhoff

Nucleic Acids Res· October 2011

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Generation of DNA nanocircles containing mismatched bases.
Yu Xiao, Caroline Jung, Andreas D Marx, Ines Winkler, Claire Wyman, Peter Friedhoff

Biotechniques· October 2011

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