Publications by authors named "Peter J Atkinson"

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Historical and Projected Impact of Global Climate Change on the Extrinsic Incubation of .
Peter Jonathon Atkinson, Torben Dahl Nielsen, Charles Caraguel

Ecol Evol· December 2025

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Heterogeneous distribution of the reported prevalence of Dirofilaria immitis infections in Australian canids - A systematic review and meta-analysis.
Peter J Atkinson, Ryan O'Handley, Torben Nielsen, Charles G B Caraguel

Prev Vet Med· April 2025

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Temperature-bounded development of Dirofilaria immitis larvae restricts the geographical distribution and seasonality of its transmission: case study and decision support system for canine heartworm management in Australia.
Peter J Atkinson, Mark Stevenson, Ryan O'Handley, Torben Nielsen, Charles G B Caraguel

Int J Parasitol· May 2024

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Advancing novel therapies for neurodegeneration through an innovative model for industry-academia collaborations: A decade of the Eisai-UCL experience.
Peter J Atkinson, Meera Swami, Nicola Ridgway, Malcolm Roberts, Jane Kinghorn

Drug Discov Today· October 2023

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Relative diagnostic accuracy of point-of-care tests to rule-in Dirofilaria immitis infection in clinically suspect dogs: A systematic review and meta-analysis.
Peter J Atkinson, Ryan O'Handley, Torben Nielsen, Charles Gb Caraguel

Prev Vet Med· August 2023

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Aleksandra Szykowska, Yu Chen, Thomas B Smith, Charlotta Preger, Jingjing Yang, Peter J Atkinson

Structure· November 2021

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Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.
Juliane Obst, Emilie Simon, Maria Martin-Estebane, Elena Pipi, Liana M Barkwill, Peter J Atkinson

Front Immunol· June 2021

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Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic Inflammation.
Matthew R Barron, Jane Gartlon, Lee A Dawson, Peter J Atkinson, Marie-Christine Pardon

Front Immunol· March 2021

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Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.
Elena Redondo-Castro, Dorte Faust, Simon Fox, Alex G Baldwin, Simon Osborne, Peter J Atkinson

Sci Rep· April 2018

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A state of delirium: Deciphering the effect of inflammation on tau pathology in Alzheimer's disease.
Matthew Barron, Jane Gartlon, Lee A Dawson, Peter J Atkinson, Marie-Christine Pardon

Exp Gerontol· August 2017

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Identification and optimisation of a series of tetrahydrobenzotriazoles as metabotropic glutamate receptor 5-selective positive allosteric modulators that improve performance in a preclinical model of cognition.
John M Ellard, Andrew Madin, Oliver Philps, Mark Hopkin, Scott Henderson, Peter J Atkinson

Bioorg Med Chem Lett· December 2015

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Sonic Hedgehog signaling in astrocytes is dependent on p38 mitogen-activated protein kinase and G-protein receptor kinase 2.
Peter J Atkinson, Tammy Dellovade, David Albers, David Von Schack, Kathryn Saraf

J Neurochem· March 2009

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ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities.
Feng Liu, Steve Grauer, Cody Kelley, Rachel Navarra, Radka Graf, Peter J Atkinson

J Pharmacol Exp Ther· December 2008

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Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels.
David R Riddell, Hua Zhou, Kevin Atchison, Helen K Warwick, Peter J Atkinson

J Neurosci· November 2008

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SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test.
Kathryn R Starr, Gary W Price, Jeannette M Watson, Peter J Atkinson, Roberto Arban

Neuropsychopharmacology· October 2007

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SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
Claire Scott, Ellen M Soffin, Matthew Hill, Peter J Atkinson, Christopher J Langmead

Eur J Pharmacol· April 2006

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Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling.
Peter J Atkinson, Kenneth W Young, Steven J Ennion, James N C Kew, Stefan R Nahorski

Mol Pharmacol· January 2006

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3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity.
Peter J Atkinson, Steven M Bromidge, Mark S Duxon, Laramie M Gaster, Michael S Hadley

Bioorg Med Chem Lett· February 2005

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Determinants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration.
Mark S Nash, Michael J Schell, Peter J Atkinson, Neil R Johnston, Stefan R Nahorski

J Biol Chem· September 2002

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