Publications by authors named "Peter Olson"

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Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer.
Kristina Drizyte-Miller, Lars D Engstrom, Jeffrey A Klomp, Clint A Stalnecker, Addison G Stamey, Peter Olson

Cancer Res· September 2025

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Impact of Co-mutations and Transcriptional Signatures in Non-Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial.
Marcelo V Negrao, Alvaro G Paula, David Molkentine, Laura Hover, Monique Nilsson, Peter Olson

Clin Cancer Res· March 2025

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Integrating epidemiology and genomics data to estimate the prevalence of acquired cysteine drug targets in the U.S. cancer patient population.
Adith S Arun, David Liarakos, Gaurav Mendiratta, Jacob Kim, George Goshua, Peter Olson

Pharmacogenomics J· March 2025

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Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trial.
Pavlos Msaouel, Kai Yu, Ying Yuan, Jianfeng Chen, Xinmiao Yan, Peter Olson

Nat Commun· January 2025

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Muscular remodeling and anteroposterior patterning during tapeworm segmentation.
Francesca Jarero, Andrew Baillie, Nick Riddiford, Jimena Montagne, Uriel Koziol, Peter D Olson

Dev Dyn· November 2024

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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.
Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Peter Olson

Cancer Discov· November 2024

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Diplomonorchis fallax n. sp. (Digenea: Monorchiidae) from the northern Gulf of Mexico with evaluation of sympatric congeners.
Stephen S Curran, Peter D Olson, Stephen A Bullard

Syst Parasitol· November 2024

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The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.
Niranjan Sudhakar, Larry Yan, Fadia Qiryaqos, Lars D Engstrom, Jade Laguer, Peter Olson

Mol Cancer Ther· October 2024

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A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma.
Pavlos Msaouel, Randy F Sweis, Manojkumar Bupathi, Elisabeth Heath, Oscar B Goodman, Peter Olson

Eur Urol Oncol· August 2024

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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Peter Olson

Science· June 2024

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Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Xinyuan Tong, Ayushi S Patel, Eejung Kim, Hongjun Li, Yueqing Chen, Peter Olson

Cancer Cell· March 2024

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Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein.
John M Ketcham, Stephen J Harwood, Ruth Aranda, Athenea N Aloiau, Briana M Bobek, Peter Olson

J Med Chem· March 2024

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Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
Christopher R Smith, Dan Chen, James G Christensen, René Coulombe, James Féthière, Peter Olson

J Med Chem· January 2024

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Highly resolved genome assembly and comparative transcriptome profiling reveal genes related to developmental stages of tapeworm .
Masoud Nazarizadeh, Milena Nováková, Marie Drábková, Julian Catchen, Peter D Olson

Proc Biol Sci· January 2024

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TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors.
A Cole Edwards, Clint A Stalnecker, Alexis Jean Morales, Khalilah E Taylor, Jennifer E Klomp, Peter Olson

Cancer Res· December 2023

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MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer.
Lars D Engstrom, Ruth Aranda, Laura Waters, Krystal Moya, Vickie Bowcut, Peter Olson

Cancer Discov· November 2023

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Building Diversity, Equity, Inclusion, and Accessibility Capacity: Resources to Promote Best Practices Among Professionals in Scholarly Publishing.
Leonard Jack, Peter J Olson, Patricia K Baskin, Otito F Iwuchukwu

Prev Chronic Dis· November 2023

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Jumping continents and major host lineages: phylogeny and diversity of the enigmatic Cryptotropidae (Platyhelminthes: Digenea).
Vasyl V Tkach, Taylor P Chermak, Kaylyn K Patitucci, Stephen E Greiman, Tran Thi Binh, Peter D Olson

Zool J Linn Soc· October 2023

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Radical Sharing: An Approach to Knowing Your Committee and Grounding Diversity Work.
Amy Ritchie Johnson, Leonard Jack, Sumi Sexton, Peter J Olson

Sci Ed· August 2023

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MRTX-500 Phase 2 Trial: Sitravatinib With Nivolumab in Patients With Nonsquamous NSCLC Progressing On or After Checkpoint Inhibitor Therapy or Chemotherapy.
Kai He, David Berz, Shirish M Gadgeel, Wade T Iams, Debora S Bruno, Peter Olson

J Thorac Oncol· July 2023

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Phase II trial of neoadjuvant sitravatinib plus nivolumab in patients undergoing nephrectomy for locally advanced clear cell renal cell carcinoma.
Jose A Karam, Pavlos Msaouel, Cara L Haymaker, Surena F Matin, Matthew T Campbell, Peter Olson

Nat Commun· May 2023

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Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors.
Christopher R Smith, Ruth Aranda, James G Christensen, Lars D Engstrom, Robin J Gunn, Peter Olson

Bioorg Med Chem· October 2022

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Anti-tumor efficacy of a potent and selective non-covalent KRAS inhibitor.
Jill Hallin, Vickie Bowcut, Andrew Calinisan, David M Briere, Lauren Hargis, Peter Olson

Nat Med· October 2022

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Intra-Atrial Right Coronary Artery and Anomalous Origin of Left Circumflex Artery Found Concurrently.
Peter C Olson, Michael Cinelli, Hamfreth S Rahming, Marc Assaad, Jonathan Spagnola

J Med Cases· October 2022

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Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction.
John M Ketcham, Jacob Haling, Shilpi Khare, Vickie Bowcut, David M Briere, Peter Olson

J Med Chem· July 2022

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