Publications by authors named "Peter S Distefano"

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Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology.
Irina U Agoulnik, Elena M Kaftanovskaya, Courtney Myhr, Ross A D Bathgate, Martina Kocan, Peter S DiStefano

Biochem Pharmacol· September 2024

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Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.
Sarah Ateaque, Spyros Merkouris, Sean Wyatt, Nicholas D Allen, Jia Xie, Peter S DiStefano

J Neurochem· June 2022

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Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons.
Charlotte Tacke, Peter S DiStefano, Ronald M Lindsay, Kristin Metzdorf, Marta Zagrebelsky

Front Mol Neurosci· June 2022

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Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.
Spyros Merkouris, Yves-Alain Barde, Kate E Binley, Nicholas D Allen, Alexey V Stepanov, Peter S DiStefano

Proc Natl Acad Sci U S A· July 2018

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Translating the human microbiome.
James Brown, Willem M de Vos, Peter S DiStefano, Joël Doré, Curtis Huttenhower

Nat Biotechnol· April 2013

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Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.
Kenneth A Longo, Elizabeth K Govek, Anna Nolan, Thomas McDonagh, Soratree Charoenthongtrakul, Peter S DiStefano

J Pharmacol Exp Ther· October 2011

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Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps.
Yong Qi, Kenneth A Longo, Derek J Giuliana, Samantha Gagne, Tom McDonagh, Peter S Distefano

BMC Physiol· January 2011

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SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183.
Julie L Huber, Michael W McBurney, Peter S Distefano, Thomas McDonagh

Future Med Chem· December 2010

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The 24-hour respiratory quotient predicts energy intake and changes in body mass.
Kenneth A Longo, Soratree Charoenthongtrakul, Derek J Giuliana, Elizabeth K Govek, Thomas McDonagh, Peter S Distefano

Am J Physiol Regul Integr Comp Physiol· March 2010

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Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.
Kenneth A Longo, Darlene E Berryman, Bruce Kelder, Soratree Charoenthongtrakul, Peter S Distefano

Growth Horm IGF Res· February 2010

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Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.
Soratree Charoenthongtrakul, Derek Giuliana, Kenneth A Longo, Elizabeth K Govek, Anna Nolan, Peter S DiStefano

J Pharmacol Exp Ther· June 2009

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Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice.
Kenneth A Longo, Soratree Charoenthongtrakul, Derek J Giuliana, Elizabeth K Govek, Thomas McDonagh, Peter S DiStefano

Regul Pept· October 2008

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Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan.
Peter S DiStefano, Rory Curtis, Bradley J Geddes

Curr Alzheimer Res· April 2007

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Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase.
Brendan Bingham, Ru Shen, Smita Kotnis, C Frederick Lo, Bradley A Ozenberger, Peter S DiStefano

Cytometry A· November 2006

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Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.
Rory Curtis, Greg O'Connor, Peter S DiStefano

Aging Cell· April 2006

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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.
Jonathan M Solomon, Rao Pasupuleti, Lei Xu, Thomas McDonagh, Rory Curtis, Peter S DiStefano

Mol Cell Biol· January 2006

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Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.
Andrew D Napper, Jeffrey Hixon, Thomas McDonagh, Kenneth Keavey, Jean-Francois Pons, Peter S DiStefano

J Med Chem· December 2005

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Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin.
Thomas McDonagh, Jeffrey Hixon, Peter S DiStefano, Rory Curtis, Andrew D Napper

Methods· August 2005

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Ageing and metabolism: drug discovery opportunities.
Rory Curtis, Bard J Geesaman, Peter S DiStefano

Nat Rev Drug Discov· July 2005

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Substrate-specific activation of sirtuins by resveratrol.
Matt Kaeberlein, Thomas McDonagh, Birgit Heltweg, Jeffrey Hixon, Eric A Westman, Peter S DiStefano

J Biol Chem· April 2005

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans.
Javier Apfeld, Greg O'Connor, Tom McDonagh, Peter S DiStefano, Rory Curtis

Genes Dev· December 2004

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Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island.
Jérôme Viala, Catherine Chaput, Ivo G Boneca, Ana Cardona, Stephen E Girardin, Peter S DiStefano

Nat Immunol· November 2004

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Functional characterization of Narc 1, a novel proteinase related to proteinase K.
Saule Naureckiene, Linh Ma, Kodangattil Sreekumar, Urmila Purandare, C Frederick Lo, Peter S DiStefano

Arch Biochem Biophys· December 2003

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Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.
Frank H Yu, Ruth E Westenbroek, Inmaculada Silos-Santiago, Kimberly A McCormick, Deborah Lawson, Peter S DiStefano

J Neurosci· August 2003

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Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan.
Stephen E Girardin, Ivo G Boneca, Leticia A M Carneiro, Aude Antignac, Muguette Jéhanno, Peter S DiStefano

Science· June 2003

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