Publications by authors named "Peter Seiler"

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Discovery and Structure-Activity Relationship of Cadazolid: A First-In-Class Quinoxolidinone Antibiotic for the Treatment of Infection.
Georg Rueedi, Philippe Panchaud, Astrid Friedli, Jean-Luc Specklin, Christian Hubschwerlen, Peter Seiler

J Med Chem· June 2024

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Integral Quadratic Constraints with Infinite-Dimensional Channels.
Aleksandr Talitckii, Matthew M Peet, Peter Seiler

Proc Am Control Conf· July 2023

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An adaptive real-time grey-box model for advanced control and operations in WRRFs.
Cheng Yang, Peter Seiler, Evangelia Belia, Glen T Daigger

Water Sci Technol· November 2021

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Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria.
Jean-Philippe Surivet, Philippe Panchaud, Jean-Luc Specklin, Stefan Diethelm, Anne-Catherine Blumstein, Peter Seiler

J Med Chem· January 2020

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Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration.
Philippe Panchaud, Jean-Philippe Surivet, Stefan Diethelm, Anne-Catherine Blumstein, Jean-Christophe Gauvin, Peter Seiler

J Med Chem· January 2020

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Single Molecule Studies Enabled by Model-Based Controller Design.
Shreyas Bhaban, Saurav Talukdar, Mingang Li, Thomas Hays, Peter Seiler

IEEE ASME Trans Mechatron· August 2018

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Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
Philippe Panchaud, Thierry Bruyère, Anne-Catherine Blumstein, Daniel Bur, Alain Chambovey, Peter Seiler

J Med Chem· May 2017

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Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria.
Jean-Philippe Surivet, Cornelia Zumbrunn, Thierry Bruyère, Daniel Bur, Christopher Kohl, Peter Seiler

J Med Chem· May 2017

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Cadazolid Does Not Promote Intestinal Colonization of Vancomycin-Resistant Enterococci in Mice.
Peter Seiler, Michel Enderlin-Paput, Philippe Pfaff, Maria Weiss, Daniel Ritz

Antimicrob Agents Chemother· January 2016

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Novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram positive activity and improved safety profile.
Jean-Philippe Surivet, Cornelia Zumbrunn, Georg Rueedi, Daniel Bur, Thierry Bruyère, Peter Seiler

J Med Chem· January 2015

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In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Hans H Locher, Peter Seiler, Xinhua Chen, Susanne Schroeder, Philippe Pfaff

Antimicrob Agents Chemother· September 2014

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Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.
Jean-Philippe Surivet, Cornelia Zumbrunn, Georg Rueedi, Christian Hubschwerlen, Daniel Bur, Peter Seiler

J Med Chem· September 2013

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Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity.
Jean-Philippe Surivet, Roland Lange, Christian Hubschwerlen, Wolfgang Keck, Jean-Luc Specklin, Peter Seiler

Bioorg Med Chem Lett· November 2012

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Evaluation of peptide nucleic acid-fluorescence in situ hybridization for identification of clinically relevant mycobacteria in clinical specimens and tissue sections.
Michael Lefmann, Birgitta Schweickert, Petra Buchholz, Ulf B Göbel, Timo Ulrichs, Peter Seiler

J Clin Microbiol· October 2006

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Alternative activation deprives macrophages of a coordinated defense program to Mycobacterium tuberculosis.
Antje Kahnert, Peter Seiler, Maik Stein, Silke Bandermann, Karin Hahnke

Eur J Immunol· March 2006

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Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guérin mutants that secrete listeriolysin.
Leander Grode, Peter Seiler, Sven Baumann, Jürgen Hess, Volker Brinkmann

J Clin Invest· September 2005

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Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.
Ann Williams, Graham J Hatch, Simon O Clark, Karen E Gooch, Kim A Hatch, Peter Seiler

Tuberculosis (Edinb)· June 2005

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Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue.
Timo Ulrichs, Michael Lefmann, Maja Reich, Lars Morawietz, Andreas Roth, Peter Seiler

J Pathol· April 2005

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Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection.
Peter Seiler, Timo Ulrichs, Silke Bandermann, Lydia Pradl, Sabine Jörg

J Infect Dis· November 2003

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Specific cytotoxic T cells eliminate cells producing neutralizing antibodies.
Oliver Planz, Peter Seiler, Hans Hengartner, Rolf M Zinkernagel

Nature· November 2003

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Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines.
Peter Seiler, Peter Aichele, Silke Bandermann, Anja E Hauser, Bao Lu

Eur J Immunol· October 2003

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Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies.
Lars Hangartner, Beatrice M Senn, Birgit Ledermann, Ulrich Kalinke, Peter Seiler

Proc Natl Acad Sci U S A· October 2003

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Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses.
Peter Aichele, Jana Zinke, Leander Grode, Reto A Schwendener, Stefan H E Kaufmann, Peter Seiler

J Immunol· August 2003

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Neutrophilia in LFA-1-deficient mice confers resistance to listeriosis: possible contribution of granulocyte-colony-stimulating factor and IL-17.
Mamiko Miyamoto, Masashi Emoto, Yoshiko Emoto, Volker Brinkmann, Izumi Yoshizawa, Peter Seiler

J Immunol· May 2003

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