Publications by authors named "Peter Tessier"

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Maximizing activity and selectivity of antibody-mediated effector functions using antibody mixtures.
Tiexin Wang, Alec A Desai, Greg M Thurber, Peter M Tessier

MAbs· December 2025

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A high-throughput platform for biophysical antibody developability assessment to enable AI/ML model training.
Ammar Arsiwala, Rebecca Bhatt, Lood van Niekerk, Porfirio Quintero-Cadena, Xiang Ao, Peter M Tessier

MAbs· December 2025

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Impacts of Antibody Structure and Mixtures on Receptor Signaling for Antibody-Dependent Cellular Cytotoxicity.
Jiakun Guan, Tiexin Wang, Peter M Tessier, Greg M Thurber

AAPS J· December 2025

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Directed evolution of drug-like Aβ conformation-specific antibodies.
Alec A Desai, Matthew D Smith, Jennifer M Zupancic, Emily K Makowski, Yulei Zhang, Peter M Tessier

Front Immunol· October 2025

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Facile generation of drug-like conformational antibodies specific for amyloid fibrils.
Alec A Desai, Jennifer M Zupancic, Hanna Trzeciakiewicz, Julia E Gerson, Kelly N DuBois, Peter M Tessier

Nat Chem Biol· June 2025

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Comparative Radiotracing Quantifies Brain Cellular Uptake and Catabolism of Bispecific Antibodies Targeting Transferrin Receptor and CD98hc.
Jacob L Veire, Michael J Lucas, Layne G Bond, Deepika R Tripu, Peter M Tessier

ACS Chem Neurosci· April 2025

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Correction: Monoclonal Antibody Generation Using Single B Cell Screening for Treating Infectious Diseases.
John S Schardt, Neelan S Sivaneri, Peter M Tessier

BioDrugs· January 2025

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TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms.
Megan M Dykstra, Kaitlin Weskamp, Nicolás B Gómez, Jacob Waksmacki, Elizabeth Tank, Peter M Tessier

Cell Rep· January 2025

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Generation of nanobodies with conformational specificity for tau oligomers that recognize tau aggregates from human Alzheimer's disease samples.
Nikki McArthur, Jay D Squire, Ogechukwu J Onyeachonam, Nemil N Bhatt, Cynthia Jerez, Peter M Tessier

Biomater Sci· November 2024

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AIntibody: an experimentally validated in silico antibody discovery design challenge.
M Frank Erasmus, Laura Spector, Fortunato Ferrara, Roberto DiNiro, Thomas J Pohl, Peter M Tessier

Nat Biotechnol· November 2024

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Deep learning-based design and experimental validation of a medicine-like human antibody library.
Nandhini Rajagopal, Udit Choudhary, Kenny Tsang, Kyle P Martin, Murat Karadag, Peter M Tessier

Brief Bioinform· November 2024

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Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates.
Nikki McArthur, Bokyung Kang, Felix G Rivera Moctezuma, Akber T Shaikh, Kathryn Loeffler, Peter M Tessier

Biotechnol Prog· October 2024

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Human antibody polyreactivity is governed primarily by the heavy-chain complementarity-determining regions.
Hsin-Ting Chen, Yulei Zhang, Jie Huang, Manali Sawant, Matthew D Smith, Peter M Tessier

Cell Rep· October 2024

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Monoclonal Antibody Generation Using Single B Cell Screening for Treating Infectious Diseases.
John S Schardt, Neelan S Sivaneri, Peter M Tessier

BioDrugs· July 2024

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TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms.
Megan M Dykstra, Kaitlin Weskamp, Nicolás B Gómez, Jacob Waksmacki, Elizabeth Tank, Peter Tessier

bioRxiv· July 2024

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Native ion mobility-mass spectrometry reveals the binding mechanisms of anti-amyloid therapeutic antibodies.
Yilin Han, Alec A Desai, Jennifer M Zupancic, Matthew D Smith, Peter M Tessier

Protein Sci· June 2024

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Facile generation of biepitopic antibodies with intrinsic agonism for activating tumor necrosis factor receptors.
Harkamal S Jhajj, John S Schardt, Namir Khalasawi, Emily L Yao, Timon S Lwo, Peter M Tessier

Cell Chem Biol· May 2024

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Auto-tuning of Antibody-Drug Conjugate Delivery for Effective Immunotherapy using High-Avidity, Low-Affinity Antibodies.
Anna Kopp, Shujun Dong, Hyeyoung Kwon, Tiexin Wang, Alec A Desai, Peter Tessier

bioRxiv· April 2024

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Reduction of monoclonal antibody viscosity using interpretable machine learning.
Emily K Makowski, Hsin-Ting Chen, Tiexin Wang, Lina Wu, Jie Huang, Peter M Tessier

MAbs· March 2024

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Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs.
Ghasidit Pornnoppadol, Layne G Bond, Michael J Lucas, Jennifer M Zupancic, Yun-Huai Kuo, Peter M Tessier

Cell Chem Biol· February 2024

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Computational optimization of antibody humanness and stability by systematic energy-based ranking.
Ariel Tennenhouse, Lev Khmelnitsky, Razi Khalaila, Noa Yeshaya, Ashish Noronha, Peter M Tessier

Nat Biomed Eng· January 2024

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Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.
Emily K Makowski, Tiexin Wang, Jennifer M Zupancic, Jie Huang, Lina Wu, Peter M Tessier

Nat Biomed Eng· January 2024

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Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily.
Harkamal S Jhajj, John S Schardt, Namir Khalasawi, Emily L Yao, Timon S Lwo, Peter M Tessier

bioRxiv· December 2023

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Simplifying complex antibody engineering using machine learning.
Emily K Makowski, Hsin-Ting Chen, Peter M Tessier

Cell Syst· August 2023

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Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates.
Jennifer M Zupancic, Matthew D Smith, Hanna Trzeciakiewicz, Mary E Skinner, Sean P Ferris, Peter M Tessier

Front Immunol· August 2023

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