Publications by authors named "Peter Tyler"

Claim this Profile
T
Transition State Analogs of Human DNPH1 Reveal Two Electrophile Migration Mechanisms.
Andrew G Wagner, Thomas B D Lang, Edward T Ledingham, Agnidipta Ghosh, Donovan Brooks, Peter C Tyler

J Med Chem· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rational synthesis of a heparan sulfate saccharide that promotes the activity of BMP2.
Karl J Shaffer, Raymond A A Smith, Alison M Daines, Xiaoman Luo, Xiaohua Lu, Peter C Tyler

Carbohydr Polym· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from -Induced Mortality.
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Peter C Tyler

ACS Infect Dis· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition.
Gabriel T Bedard, Nord Gilaj, Karina Peregrina, Isabella Brew, Elena Tosti, Peter C Tyler

J Biol Chem· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhancing BMP-2-mediated osteogenesis with a synthetic heparan sulfate mimetic.
Raymond A A Smith, Xiaoman Luo, Xiaohua Lu, Tuan Chun Tan, Bach Q Le, Peter C Tyler

Biomater Adv· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality.
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Peter C Tyler

bioRxiv· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles.
C H Andy Wong, Jonathan G Hubert, Kevin J Sparrow, Lawrence D Harris, Peter C Tyler

Org Biomol Chem· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Kinetic and Structural Characterization of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors.
Kayla Glockzin, Kathleen M Meneely, Ryan Hughes, Sean W Maatouk, Grace E Piña, Peter C Tyler

Biochemistry· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Residence Times for Femtomolar and Picomolar Inhibitors of MTANs.
Morais Brown, Peter C Tyler, Vern L Schramm

Biochemistry· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition and Mechanism of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase.
Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Rodrigo G Ducati, Agnidipta Ghosh, Peter C Tyler

ACS Chem Biol· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues.
Sinan Gai, Kajitha Suthagar, Karl J Shaffer, Wanting Jiao, Yacoba V T Minnow, Peter C Tyler

Bioorg Med Chem· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Kinetic Characterization and Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferases.
Kayla Glockzin, Demetrios Kostomiris, Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Peter C Tyler

Biochemistry· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1.
Farah Lamiable-Oulaidi, Rajesh K Harijan, Karl J Shaffer, Douglas R Crump, Yan Sun, Peter C Tyler

J Med Chem· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues.
Ashleigh S Paparella, Briana L Aboulache, Rajesh K Harijan, Kathryn S Potts, Peter C Tyler

Nat Commun· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aminofutalosine Deaminase in the Menaquinone Pathway of .
Mu Feng, Rajesh K Harijan, Lawrence D Harris, Peter C Tyler, Richard F G Fröhlich

Biochemistry· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rethinking the political economy of place: challenges of productivity and inclusion.
Emil Evenhuis, Neil Lee, Ron Martin, Peter Tyler

Camb J Reg Econ Soc· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparison of disaccharide donors for heparan sulfate synthesis: uronic acids vs. their pyranose equivalents.
Daniel J Sheppard, Scott A Cameron, Peter C Tyler, Ralf Schwörer

Org Biomol Chem· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The post-lockdown period should be used to acquire effective therapies for future resurgence in SARS-Cov-2 infections.
Kurt L Krause, Richard Furneaux, Paul Benjes, Margaret Brimble, Tony Davidson, Peter Tyler

N Z Med J· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides.
Rebecca L Miller, Scott E Guimond, Ralf Schwörer, Olga V Zubkova, Peter C Tyler

Nat Commun· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases.
Di Zhang, Brandon E Burdette, Zhengyu Wang, Kumari Karn, Hong-Yu Li, Peter C Tyler

Biochemistry· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolic dependency of chorismate in Plasmodium falciparum suggests an alternative source for the ubiquinone biosynthesis precursor.
Ana Lisa Valenciano, Maria L Fernández-Murga, Emilio F Merino, Nicole R Holderman, Grant J Butschek, Peter C Tyler

Sci Rep· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.
Rajesh K Harijan, Oskar Hoff, Rodrigo G Ducati, Ross S Firestone, Brett M Hirsch, Peter C Tyler

J Med Chem· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors.
Darshita Budhadev, Karinna Saxby, Julia Walton, Gideon Davies, Peter C Tyler

Org Biomol Chem· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy.
Olga V Zubkova, Yassir A Ahmed, Scott E Guimond, Sophia-Louise Noble, John Holmes Miller, Peter C Tyler

ACS Chem Biol· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The transition to magic bullets - transition state analogue drug design.
Gary B Evans, Vern L Schramm, Peter C Tyler

Medchemcomm· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis