Publications by authors named "Peter W Halcrow"

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Involvement of endolysosome iron in HIV-1 gp120-, morphine-, and iron supplementation-induced disruption of the reactive species interactome and induction of neurotoxicity.
Nirmal Kumar, Peter W Halcrow, Darius N K Quansah, Braelyn Liang, Olimpia Meucci

Redox Rep· December 2025

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Involvement of Endolysosomes and Aurora Kinase A in the Regulation of Amyloid β Protein Levels in Neurons.
Zahra Afghah, Nabab Khan, Gaurav Datta, Peter W Halcrow, Jonathan D Geiger

Int J Mol Sci· June 2024

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HERV-K (HML-2) Envelope Protein Induces Mitochondrial Depolarization and Neurotoxicity via Endolysosome Iron Dyshomeostasis.
Peter W Halcrow, Darius N K Quansah, Nirmal Kumar, Joseph P Steiner, Avindra Nath

J Neurosci· April 2024

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Weak base drug-induced endolysosome iron dyshomeostasis controls the generation of reactive oxygen species, mitochondrial depolarization, and cytotoxicity.
Peter W Halcrow, Darius N K Quansah, Nirmal Kumar, Rebecca L Solloway, Kayla M Teigen

NeuroImmune Pharm Ther· March 2024

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Mu opioid receptor-mediated release of endolysosome iron increases levels of mitochondrial iron, reactive oxygen species, and cell death.
Peter W Halcrow, Nirmal Kumar, Emily Hao, Nabab Khan, Olimpia Meucci

NeuroImmune Pharm Ther· March 2023

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HIV-1 gp120-Induced Endolysosome de-Acidification Leads to Efflux of Endolysosome Iron, and Increases in Mitochondrial Iron and Reactive Oxygen Species.
Peter W Halcrow, Koffi L Lakpa, Nabab Khan, Zahra Afghah, Nicole Miller

J Neuroimmune Pharmacol· June 2022

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Endolysosome Iron Chelation Inhibits HIV-1 Protein-Induced Endolysosome De-Acidification-Induced Increases in Mitochondrial Fragmentation, Mitophagy, and Cell Death.
Peter W Halcrow, Nirmal Kumar, Darius N K Quansah, Aparajita Baral, Braelyn Liang

Cells· May 2022

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Heterogeneity of ferrous iron-containing endolysosomes and effects of endolysosome iron on endolysosome numbers, sizes, and localization patterns.
Peter W Halcrow, Nirmal Kumar, Zahra Afghah, Jalyn P Fischer, Nabab Khan

J Neurochem· April 2022

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HIV-1 Tat endocytosis and retention in endolysosomes affects HIV-1 Tat-induced LTR transactivation in astrocytes.
Nabab Khan, Peter W Halcrow, Zahra Afghah, Aparajita Baral, Jonathan D Geiger

FASEB J· March 2022

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Role of endolysosome function in iron metabolism and brain carcinogenesis.
Peter W Halcrow, Miranda L Lynch, Jonathan D Geiger, Joyce E Ohm

Semin Cancer Biol· November 2021

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Endolysosome iron restricts Tat-mediated HIV-1 LTR transactivation by increasing HIV-1 Tat oligomerization and β-catenin expression.
Nabab Khan, Peter W Halcrow, Leo K Lakpa, Mohd Rehan, Xuesong Chen

J Neurovirol· October 2021

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SARS-CoV-2 S1 Protein Induces Endolysosome Dysfunction and Neuritic Dystrophy.
Gaurav Datta, Nicole M Miller, Peter W Halcrow, Nabab Khan, Timothy Colwell

Front Cell Neurosci· October 2021

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Overcoming Chemoresistance: Altering pH of Cellular Compartments by Chloroquine and Hydroxychloroquine.
Peter W Halcrow, Jonathan D Geiger, Xuesong Chen

Front Cell Dev Biol· February 2021

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Two-pore channels regulate Tat endolysosome escape and Tat-mediated HIV-1 LTR transactivation.
Nabab Khan, Peter W Halcrow, Koffi L Lakpa, Zahra Afghah, Nicole M Miller

FASEB J· March 2020

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Readily Releasable Stores of Calcium in Neuronal Endolysosomes: Physiological and Pathophysiological Relevance.
Koffi L Lakpa, Peter W Halcrow, Xuesong Chen, Jonathan D Geiger

Adv Exp Med Biol· October 2019

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BK channels regulate extracellular Tat-mediated HIV-1 LTR transactivation.
Nabab Khan, Koffi L Lakpa, Peter W Halcrow, Zahra Afghah, Nicole M Miller

Sci Rep· August 2019

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