Publications by authors named "Petr Chlapek"

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Thiosemicarbazones and selected tyrosine kinase inhibitors synergize in pediatric solid tumors: NDRG1 upregulation and impaired prosurvival signaling in neuroblastoma cells.
Maria Krchniakova, Silvia Paukovcekova, Petr Chlapek, Jakub Neradil, Jan Skoda

Front Pharmacol· September 2022

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Thiosemicarbazones Can Act Synergistically with Anthracyclines to Downregulate CHEK1 Expression and Induce DNA Damage in Cell Lines Derived from Pediatric Solid Tumors.
Silvia Paukovcekova, Maria Krchniakova, Petr Chlapek, Jakub Neradil, Jan Skoda

Int J Mol Sci· August 2022

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Serotonin limits generation of chromaffin cells during adrenal organ development.
Polina Kameneva, Victoria I Melnikova, Maria Eleni Kastriti, Anastasia Kurtova, Emil Kryukov, Petr Chlapek

Nat Commun· May 2022

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A selective p53 activator and anticancer agent to improve colorectal cancer therapy.
Helena Ramos, Maria I L Soares, Joana Silva, Liliana Raimundo, Juliana Calheiros, Petr Chlapek

Cell Rep· April 2021

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Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular Mechanisms.
Silvia Paukovcekova, Jan Skoda, Jakub Neradil, Erika Mikulenkova, Petr Chlapek

Cancers (Basel)· December 2020

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Repurposing Tyrosine Kinase Inhibitors to Overcome Multidrug Resistance in Cancer: A Focus on Transporters and Lysosomal Sequestration.
Maria Krchniakova, Jan Skoda, Jakub Neradil, Petr Chlapek, Renata Veselska

Int J Mol Sci· April 2020

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Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers.
Viera Dobrotkova, Petr Chlapek, Marta Jezova, Katerina Adamkova, Pavel Mazanek

PLoS One· February 2020

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Comparative Analysis of Putative Prognostic and Predictive Markers in Neuroblastomas: High Expression of PBX1 Is Associated With a Poor Response to Induction Therapy.
Renata Veselska, Marta Jezova, Michal Kyr, Pavel Mazanek, Petr Chlapek

Front Oncol· November 2019

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New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.
Sara Gomes, Liliana Raimundo, Joana Soares, Joana B Loureiro, Mariana Leão, Petr Chlapek

Cancer Lett· April 2019

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Traffic lights for retinoids in oncology: molecular markers of retinoid resistance and sensitivity and their use in the management of cancer differentiation therapy.
Viera Dobrotkova, Petr Chlapek, Pavel Mazanek, Jaroslav Sterba, Renata Veselska

BMC Cancer· November 2018

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Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids.
Petr Chlapek, Viera Slavikova, Pavel Mazanek, Jaroslav Sterba, Renata Veselska

Int J Mol Sci· January 2018

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Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups.
Petr Chlapek, Karel Zitterbart, Leos Kren, Lenka Filipova, Jaroslav Sterba

PLoS One· August 2017

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LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines.
Miroslava Krzyzankova, Silvia Chovanova, Petr Chlapek, Matej Radsetoulal, Jakub Neradil

Tumour Biol· August 2014

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The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression.
Petr Chlapek, Jakub Neradil, Martina Redova, Karel Zitterbart, Jaroslav Sterba

Cancer Cell Int· June 2014

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CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines.
Jiri Sana, Iva Zambo, Jan Skoda, Jakub Neradil, Petr Chlapek

Anal Cell Pathol (Amst)· August 2012

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Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study.
Petr Chlapek, Martina Redova, Karel Zitterbart, Marketa Hermanova, Jaroslav Sterba

J Exp Clin Cancer Res· May 2010

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Influence of LOX/COX inhibitors on cell differentiation induced by all-trans retinoic acid in neuroblastoma cell lines.
Martina Redova, Petr Chlapek, Tomas Loja, Karel Zitterbart, Marketa Hermanova

Int J Mol Med· February 2010

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Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin.
Tomas Loja, Petr Chlapek, Petr Kuglik, Martina Pesakova, Alexandra Oltova

Oncol Rep· January 2009

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Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines.
Renata Veselska, Marketa Hermanova, Tomas Loja, Petr Chlapek, Iva Zambo

BMC Cancer· October 2008

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