Publications by authors named "Philip Coates"

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Reduced structural rigidity of MDMX protein enhances binding to TP53 mRNA.
Martina Kucerikova, Ondrej Bonczek, Vanesa Olivares-Illana, Andres Rodriguez-Rodriguez, Jose G Sampedro, Philip J Coates

Biosci Rep· November 2025

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CDK11 inhibition induces cytoplasmic p21 splice variant by p53 stabilisation and SF3B1 inactivation.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Philip J Coates

Mol Oncol· October 2025

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A Unique Plasma Protein Signature Characterizes Squamous Cell Carcinoma of the Oral Tongue in Young Adults.
Xiaolian Gu, Philip J Coates, Lixiao Wang, Sivakumar Vadivel Gnanasundram, Nicola Sgaramella

J Oral Pathol Med· September 2025

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Heterogeneous protein dynamics links to mitochondrial activity, glucose transporter, and ALDH cancer stem cell properties.
Martin Krkoška, Zuzana Tylichová, Pavlína Zatloukalová, Petr Müller, Bořivoj Vojtěšek, Philip John Coates

BMC Cancer· July 2025

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Automated tumor-stroma ratio estimation for improved prognostic stratification of squamous cell carcinoma of the oral tongue.
Lixiao Wang, Katrine Sörensen, Philip J Coates, Xiaolian Gu, Nicola Sgaramella

J Pathol Clin Res· July 2025

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TAp73 and ΔTAp73 isoforms show cell-type specific distributions and alterations in cancer.
Vaclav Hrabal, Michaela Stenckova, Filip Zavadil Kokas, Petr Muller, Rudolf Nenutil, Philip J Coates

Sci Rep· December 2024

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Re-appraising the evidence for the source, regulation and function of p53-family isoforms.
Ignacio López, Irene Larghero Valdivia, Borivoj Vojtesek, Robin Fåhraeus, Philip J Coates

Nucleic Acids Res· November 2024

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Direct activation of HSF1 by macromolecular crowding and misfolded proteins.
Oliver Simoncik, Vlastimil Tichy, Michal Durech, Lenka Hernychova, Filip Trcka, Philip J Coates

PLoS One· November 2024

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Inverse correlation between TP53 gene status and PD-L1 protein levels in a melanoma cell model depends on an IRF1/SOX10 regulatory axis.
Lucia Martinkova, Pavlina Zatloukalova, Martina Kucerikova, Nela Friedlova, Zuzana Tylichova, Philip John Coates

Cell Mol Biol Lett· September 2024

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Upregulation of Apoptosis Related Genes in Clinically Normal Tongue Contralateral to Squamous Cell Carcinoma of the Oral Tongue, an Effort to Maintain Tissue Homeostasis.
Nima Attaran, Philip J Coates, Katarina Zborayova, Nicola Sgaramella, Karin Nylander

Head Neck Pathol· September 2024

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Patients with oral tongue squamous cell carcinoma and co‑existing diabetes exhibit lower recurrence rates and improved survival: Implications for treatment.
Amir M Salehi, Lixiao Wang, Xiaolian Gu, Philip J Coates, Lena Norberg Spaak

Oncol Lett· April 2024

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Complex and variable regulation of ΔNp63 and TAp63 by TGFβ has implications for the dynamics of squamous cell epithelial to mesenchymal transition.
Zuzana Pokorná, Zuzana Tylichová, Borivoj Vojtesek, Philip J Coates

Sci Rep· March 2024

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ΔNp63 is regulated by insulin/IGF-1 signaling in normal basal/progenitor mammary cells and in luminal-type breast cancer cells.
Michaela Stenckova, Yajing Liu, Marta Nekulova, Jitka Holcakova, Zuzana Pokorna, Philip John Coates

Neoplasma· October 2023

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Early detection of squamous cell carcinoma of the oral tongue using multidimensional plasma protein analysis and interpretable machine learning.
Xiaolian Gu, Amir Salehi, Lixiao Wang, Philip J Coates, Nicola Sgaramella

J Oral Pathol Med· August 2023

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Recent Advances in Pathology: the 2023 Annual Review Issue of The Journal of Pathology.
J Louise Jones, Richard Poulsom, Philip J Coates

J Pathol· August 2023

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Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue.
Xiaolian Gu, Lixiao Wang, Philip J Coates, Sivakumar Vadivel Gnanasundram, Nicola Sgaramella

J Pathol· January 2023

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Antigen peptide transporters are upregulated in squamous cell carcinoma of the oral tongue and show sex-specific associations with survival.
Nima Attaran, Philip J Coates, Katarina Zborayova, Baris Erdogan, Mustafa Magan

Oncol Lett· November 2022

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Reiterative modeling of combined transcriptomic and proteomic features refines and improves the prediction of early recurrence in squamous cell carcinoma of head and neck.
Amir Salehi, Lixiao Wang, Philip J Coates, Lena Norberg Spaak, Xiaolian Gu

Comput Biol Med· October 2022

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Stat3 Tyrosine 705 and Serine 727 Phosphorylation Associate With Clinicopathological Characteristics and Distinct Tumor Cell Phenotypes in Triple-Negative Breast Cancer.
Michaela Stenckova, Rudolf Nenutil, Borivoj Vojtesek, Philip J Coates

Pathol Oncol Res· August 2022

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Recent Advances in Pathology: the 2022 Annual Review Issue of The Journal of Pathology.
C Simon Herrington, Richard Poulsom, Nischalan Pillay, Peter Bankhead, Philip J Coates

J Pathol· July 2022

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DNA Demethylation Switches Oncogenic ΔNp63 to Tumor Suppressive TAp63 in Squamous Cell Carcinoma.
Zuzana Pokorna, Vaclav Hrabal, Vlastimil Tichy, Borivoj Vojtesek, Philip J Coates

Front Oncol· July 2022

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Identifying pathways regulating the oncogenic p53 family member ΔNp63 provides therapeutic avenues for squamous cell carcinoma.
Zuzana Pokorna, Jan Vyslouzil, Borivoj Vojtesek, Philip J Coates

Cell Mol Biol Lett· February 2022

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Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them?
Lucia Haronikova, Ondrej Bonczek, Pavlina Zatloukalova, Filip Kokas-Zavadil, Martina Kucerikova, Philip J Coates

Cell Mol Biol Lett· December 2021

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Variation in Plasma Levels of TRAF2 Protein During Development of Squamous Cell Carcinoma of the Oral Tongue.
Xiaolian Gu, Philip Coates, Lixiao Wang, Baris Erdogan, Amir Salehi

Front Oncol· November 2021

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Recent Advances in Pathology: the 2021 Annual Review Issue of The Journal of Pathology.
C Simon Herrington, Richard Poulsom, Hartmut Koeppen, Philip J Coates

J Pathol· July 2021

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