Publications by authors named "Philip Insel"

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Accelerated Cognitive Decline in Late Life Depression: The Role of Amyloid-β, Cortico-Limbic Volume, and White Matter Hyperintensities.
Emma Rhodes, Philip S Insel, Michelle Kassel, Maria Kryza-Lacombe, Meryl A Butters

Am J Geriatr Psychiatry· February 2026

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Response to "Brain Amyloid and Cognitive Decline in Late-Life Depression".
Emma Rhodes, Philip S Insel, Michelle Kassel, Maria Kryza-Lacombe, Meryl A Butters

Am J Geriatr Psychiatry· February 2026

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Characterizing amyloid and tau positron emission tomography-based stages across the clinical continuum.
Karly A Cody, Andrzej Sokołowski, Emily Johns, Lucah Medina Guerra, Joseph R Winer, Philip S Insel

Alzheimers Dement· January 2026

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Divergent latent classes of cognitive decline in the A4 and LEARN studies.
Runpeng Li, Oliver Langford, Philip S Insel, Reisa A Sperling, Rema Raman

medRxiv· December 2025

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Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease.
Philip S Insel, Niklas Mattsson-Carlgren, Oliver Langford, Vincent M Caruso, Antoine Leuzy

JAMA Neurol· October 2025

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Comparison of amyloid PET acquired through standardized and unstandardized protocols.
Karly A Cody, Andrzej Sokolowski, Lucah Medina Guerra, Philip S Insel, William J Jagust

Alzheimers Dement· September 2025

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Continuum of Core 1 Biomarkers in Preclinical Alzheimer's Disease.
Leonardino A Digma, Christina B Young, Joseph R Winer, Karly A Cody, Kyan Younes, Philip S Insel

medRxiv· September 2025

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Characterizing amyloid and tau PET-based stages across the clinical continuum.
Karly A Cody, Andrzej Sokołowski, Emily Johns, Lucah Medina Guerra, Joseph R Winer, Philip S Insel

medRxiv· September 2025

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Test taking location and practice effects as factors contributing to scores on remotely administered neurocognitive performance tests in a sample of older adults.
R Scott Mackin, Emily Burns, Philip Insel, Nithya Ganesh, Michelle Kassel

Appl Neuropsychol Adult· July 2025

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Cortico-limbic volume abnormalities in late life depression are distinct from β amyloid and white matter pathologies.
R Scott Mackin, Emma Rhodes, Michelle Kassel, Maria Kryza-Lacombe, Emily Burns, Philip S Insel

Mol Psychiatry· April 2025

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Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability.
Maria Kryza-Lacombe, Michelle T Kassel, Philip S Insel, Emma Rhodes, David Bickford

Int Psychogeriatr· November 2024

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Anxiety in late-life depression is associated with poorer performance across multiple cognitive domains.
Maria Kryza-Lacombe, Michelle T Kassel, Philip S Insel, Emma Rhodes, David Bickford

J Int Neuropsychol Soc· November 2024

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Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.
Antoine Leuzy, Lars Lau Raket, Victor L Villemagne, Gregory Klein, Matteo Tonietto, Philip S Insel

Alzheimers Dement· September 2024

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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
Hannah Baumeister, Jacob W Vogel, Philip S Insel, Luca Kleineidam, Steffen Wolfsgruber

Brain· July 2024

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Relationship of Hoarding and Depression Symptoms in Older Adults.
Sara Nutley, Binh K Nguyen, Robert Scott Mackin, Philip S Insel, Duygu Tosun

Am J Geriatr Psychiatry· April 2024

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Speech patterns during memory recall relates to early tau burden across adulthood.
Christina B Young, Viktorija Smith, Cody Karjadi, Selah-Marie Grogan, Ting Fang Alvin Ang, Philip S Insel

Alzheimers Dement· April 2024

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Hoarding Symptoms in Late Life Depression are Associated With Greater Executive Dysfunction and Disability and Poorer Response to Depression Treatment.
Michelle T Kassel, Maria Kryza-Lacombe, Philip S Insel, Emma Rhodes, Derek D Satre

Am J Geriatr Psychiatry· February 2024

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Genetic Moderation of the Association of β-Amyloid With Cognition and MRI Brain Structure in Alzheimer Disease.
Philip S Insel, Atul Kumar, Oskar Hansson, Niklas Mattsson-Carlgren,

Neurology· July 2023

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Natural cubic splines for the analysis of Alzheimer's clinical trials.
Michael C Donohue, Oliver Langford, Philip S Insel, Christopher H van Dyck, Ronald C Petersen

Pharm Stat· May 2023

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Tau positron emission tomography in preclinical Alzheimer's disease.
Philip S Insel, Christina B Young, Paul S Aisen, Keith A Johnson, Reisa A Sperling

Brain· February 2023

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The genetic regulation of protein expression in cerebrospinal fluid.
Oskar Hansson, Atul Kumar, Shorena Janelidze, Erik Stomrud, Philip S Insel

EMBO Mol Med· January 2023

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APOE effects on regional tau in preclinical Alzheimer's disease.
Christina B Young, Emily Johns, Gabriel Kennedy, Michael E Belloy, Philip S Insel

Mol Neurodegener· January 2023

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Cognitive outcomes are differentially associated with depression severity trajectories during psychotherapy treatment for late life major depressive disorder.
Michelle T Kassel, Emma Rhodes, Philip S Insel, Kai Woodworth, Christina Garrison-Diehn

Int J Geriatr Psychiatry· August 2022

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Uncertainties in the PET defined A-/T+ subtype.
Elizabeth C Mormino, Philip S Insel

Alzheimers Dement (Amst)· August 2022

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Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired Adults.
Philip S Insel, Brian S Mohlenhoff, Thomas C Neylan, Andrew D Krystal, R Scott Mackin

JAMA Netw Open· July 2021

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