Publications by authors named "Philipp Leippe"

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Glutamate indicators with increased sensitivity and tailored deactivation rates.
Abhi Aggarwal, Adrian Negrean, Yang Chen, Rishyashring Iyer, Daniel Reep, Philipp Leippe

Nat Methods· December 2025

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Metabolic mapping of the human solute carrier superfamily.
Tabea Wiedmer, Shao Thing Teoh, Eirini Christodoulaki, Gernot Wolf, Chengzhe Tian, Philipp Leippe

Mol Syst Biol· June 2025

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The genetic interaction map of the human solute carrier superfamily.
Gernot Wolf, Philipp Leippe, Svenja Onstein, Ulrich Goldmann, Fabian Frommelt

Mol Syst Biol· June 2025

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The solute carrier superfamily interactome.
Fabian Frommelt, Rene Ladurner, Ulrich Goldmann, Gernot Wolf, Alvaro Ingles-Prieto, Philipp Leippe

Mol Syst Biol· June 2025

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Data- and knowledge-derived functional landscape of human solute carriers.
Ulrich Goldmann, Tabea Wiedmer, Andrea Garofoli, Vitaly Sedlyarov, Manuel Bichler, Philipp Leippe

Mol Syst Biol· June 2025

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Optical control of cardiac electrophysiology by the photochromic ligand azobupivacaine 2.
Timm Fehrentz, Ehsan Amin, Nicole Görldt, Tobias Strasdeit, Seyed-Erfan Moussavi-Torshizi, Philipp Leippe

Br J Pharmacol· March 2025

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Glutamate indicators with increased sensitivity and tailored deactivation rates.
Abhi Aggarwal, Adrian Negrean, Yang Chen, Rishyashring Iyer, Daniel Reep, Philipp Leippe

bioRxiv· March 2025

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Cell-Specific Optical Control of AMPA Glutamate Receptors with a Photoswitchable Tethered Antagonist.
Philipp Leippe, Prashant Donthamsetti, Tongil Ko, Cherise Stanley, Ehud Isacoff

Angew Chem Int Ed Engl· December 2024

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AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells.
Lars Hellweg, Martin Pfeifer, Miroslaw Tarnawski, Shao Thing-Teoh, Lena Chang, Philipp Leippe

Cell Chem Biol· August 2024

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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.
Daniela Digles, Alvaro Ingles-Prieto, Vojtech Dvorak, Tamara A M Mocking, Ulrich Goldmann, Philipp Leippe

Front Pharmacol· July 2024

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Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells.
Miroslav Kosar, David A Sykes, Alexander E G Viray, Rosa Maria Vitale, Roman C Sarott, Philipp Leippe

J Am Chem Soc· July 2023

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An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters.
Vojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, Patrick Altermatt, Helena Batoulis, Philipp Leippe

Front Pharmacol· August 2021

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Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ).
Konstantin Hinnah, Sabine Willems, Johannes Morstein, Jan Heering, Felix W W Hartrampf, Philipp Leippe

J Med Chem· October 2020

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The RESOLUTE consortium: unlocking SLC transporters for drug discovery.
Giulio Superti-Furga, Daniel Lackner, Tabea Wiedmer, Alvaro Ingles-Prieto, Barbara Barbosa, Philipp Leippe

Nat Rev Drug Discov· July 2020

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Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors.
Philipp Leippe, Johannes Broichhagen, Katia Cailliau, Alexandra Mougel, Marion Morel

Angew Chem Int Ed Engl· April 2020

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Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.
Martin S Maier, Katharina Hüll, Martin Reynders, Bryan S Matsuura, Philipp Leippe

J Am Chem Soc· October 2019

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Designing azobenzene-based tools for controlling neurotransmission.
Philipp Leippe, James Allen Frank

Curr Opin Struct Biol· August 2019

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Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine.
Philipp Leippe, Nils Winter, Martin P Sumser, Dirk Trauner

ACS Chem Neurosci· December 2018

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Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.
Tom Podewin, Julia Ast, Johannes Broichhagen, Nicholas H F Fine, Daniela Nasteska, Philipp Leippe

ACS Cent Sci· February 2018

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Synthesis of Photoswitchable Δ-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.
Matthias V Westphal, Michael A Schafroth, Roman C Sarott, Michael A Imhof, Christian P Bold, Philipp Leippe

J Am Chem Soc· December 2017

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Specificity and Speed: Tethered Photopharmacology.
Philipp Leippe, Julia Koehler Leman, Dirk Trauner

Biochemistry· October 2017

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Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.
Joshua Levitz, Johannes Broichhagen, Philipp Leippe, David Konrad, Dirk Trauner

Proc Natl Acad Sci U S A· April 2017

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Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.
Johannes Broichhagen, Arunas Damijonaitis, Joshua Levitz, Kevin R Sokol, Philipp Leippe

ACS Cent Sci· October 2015

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