Publications by authors named "Philipp Trepte"

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AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Philipp Trepte, Christopher Secker, Julien Olivet, Jeremy Blavier, Simona Kostova

Mol Syst Biol· April 2024

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AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B Maseko, Soon Gang Choi

bioRxiv· June 2023

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Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids.
Jaydeep Sidhaye, Philipp Trepte, Natalie Sepke, Maria Novatchkova, Michael Schutzbier

Elife· March 2023

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CellFIE: CRISPR- and Cell Fusion-based Two-hybrid Interaction Mapping of Endogenous Proteins.
Christopher Secker, Simona Kostova, Hannah Niederlechner, Stephanie Beetz, Ina Wendland, Philipp Trepte

J Mol Biol· December 2021

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The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Erich E Wanker, Anne Ast, Franziska Schindler, Philipp Trepte, Sigrid Schnoegl

J Neurochem· November 2019

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Maximizing binary interactome mapping with a minimal number of assays.
Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Philipp Trepte

Nat Commun· August 2019

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LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru

Mol Syst Biol· July 2018

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Current Approaches Toward Quantitative Mapping of the Interactome.
Alexander Buntru, Philipp Trepte, Konrad Klockmeier, Sigrid Schnoegl, Erich E Wanker

Front Genet· May 2016

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DULIP: A Dual Luminescence-Based Co-Immunoprecipitation Assay for Interactome Mapping in Mammalian Cells.
Philipp Trepte, Alexander Buntru, Konrad Klockmeier, Lindsay Willmore, Anup Arumughan

J Mol Biol· October 2015

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Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures.
Philipp Trepte, Nadine Strempel, Erich E Wanker

Essays Biochem· May 2015

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Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins.
Katie J Wolfe, Hong Yu Ren, Philipp Trepte, Douglas M Cyr

PLoS One· December 2014

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The Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins.
Katie J Wolfe, Hong Yu Ren, Philipp Trepte, Douglas M Cyr

Mol Biol Cell· December 2013

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