Publications by authors named "Philippe Lesnik"

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Regulation of HDL dysfunctionality by phosphatidylethanolamine links poly-unsaturated fatty acids with atherosclerotic cardiovascular diseases.
Malik Taradeh, Lise M Hardy, Veronica D Dahik, Marie Lhomme, Hua Wang, Philippe Lesnik

Mol Metab· November 2025

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Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions.
Juliette Tokgozoglu, Valeria Pistorio, Mirko Minini, Pierre-Antoine Soret, Virginie Steunou, Philippe Lesnik

Cell Death Dis· October 2025

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Defective biological activities of high-density lipoprotein identify patients at highest risk of recurrent cardiovascular event.
Johanne Silvain, Clément Materne, Michel Zeitouni, Niki Procopi, Paul Guedeney, Philippe Lesnik

Eur J Prev Cardiol· September 2025

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MAIT Cells Promote Cholesterol Excretion Pathways Mitigating Atherosclerosis.
Hua Wang, Pukar Kc, Kaidi Zhang, Clément Materne, Marie Lhomme, Philippe Lesnik

Circ Res· April 2025

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ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Veronica D Dahik, Pukar Kc, Clément Materne, Canelle Reydellet, Marie Lhomme, Philippe Lesnik

Sci Transl Med· December 2024

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Establishing a multi-specialty consensus in the clinical need for hypercholesterolemia management and its implication for patients access to innovative therapies.
Franck Boccara, Pierre Sabouret, Catherine Boileau, Jean-Louis Georges, Christophe Leclercq, Philippe Lesnik

Panminerva Med· March 2024

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Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases.
Camille d'Humières, Margot Delavy, Laurie Alla, Farid Ichou, Emilie Gauliard, Philippe Lesnik

Microbiome· March 2024

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Targeted delivery of LXR-agonists to atherosclerotic lesions mediated by polydiacetylene micelles.
Lucie Jamgotchian, Laurent Devel, Robert Thai, Lucie Poupel, Thierry Huby, Philippe Lesnik

Nanoscale· November 2023

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Impaired metabolism predicts coronary artery calcification in women with systemic lupus erythematosus.
Fanny Urbain, Maharajah Ponnaiah, Farid Ichou, Marie Lhomme, Clément Materne, Philippe Lesnik

EBioMedicine· October 2023

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Short-chain fatty acids levels in human milk are not affected by holder pasteurization and high hydrostatic pressure processing.
Lucie Marousez, Farid Ichou, Philippe Lesnik, Léa Chantal Tran, Marie De Lamballerie

Front Pediatr· September 2023

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Identification of the specific molecular and functional signatures of pre-beta-HDL: relevance to cardiovascular disease.
Isabelle Guillas, Marie Lhomme, Cédric Pionneau, Lucrèce Matheron, Maharajah Ponnaiah, Philippe Lesnik

Basic Res Cardiol· August 2023

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Corrigendum to "Phospholipid transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis is directly correlated with HDL-cholesterol levels and is not associated with cardiovascular risk" [Atherosclerosis 324C (2021) 1-8].
Feng Ma, Maryam Darabi, Marie Lhomme, Emilie Tubeuf, Aurélie Canicio, Philippe Lesnik

Atherosclerosis· May 2023

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Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in 78 patients from a single center.
Fleur Cohen Aubart, Lucie Poupel, Flora Saint-Charles, Frederic Charlotte, Youssef Arsafi, Philippe Lesnik

Haematologica· June 2022

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Phosphatidylserine enhances anti-inflammatory effects of reconstituted HDL in macrophages via distinct intracellular pathways.
Maryam Darabi, Marie Lhomme, Veronica D Dahik, Isabelle Guillas, Eric Frisdal, Philippe Lesnik

FASEB J· May 2022

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Diurnal Interplay between Epithelium Physiology and Gut Microbiota as a Metronome for Orchestrating Immune and Metabolic Homeostasis.
Juan Jose Martínez-García, Dominique Rainteau, Lydie Humbert, Antonin Lamaziere, Philippe Lesnik

Metabolites· April 2022

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Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases.
Emelyne Lécuyer, Tiphaine Le Roy, Aurélie Gestin, Amélie Lacombe, Catherine Philippe, Philippe Lesnik

Diabetes· September 2021

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Phospholipid transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis is directly correlated with HDL-cholesterol levels and is not associated with cardiovascular risk.
Feng Ma, Maryam Darabi, Marie Lhomme, Emilie Tubeuf, Aurélie Canicio, Philippe Lesnik

Atherosclerosis· May 2021

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Ex-Vivo Pharmacological Defatting of the Liver: A Review.
Claire Goumard, Célia Turco, Mehdi Sakka, Lynda Aoudjehane, Philippe Lesnik

J Clin Med· March 2021

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Distinct Postprandial Bile Acids Responses to a High-Calorie Diet in Men Volunteers Underscore Metabolically Healthy and Unhealthy Phenotypes.
Antonin Lamaziere, Dominique Rainteau, Pukar Kc, Lydie Humbert, Emilie Gauliard, Philippe Lesnik

Nutrients· November 2020

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Interleukin-1β and Risk of Premature Death in Patients With Myocardial Infarction.
Johanne Silvain, Mathieu Kerneis, Michel Zeitouni, Benoit Lattuca, Sophie Galier, Philippe Lesnik

J Am Coll Cardiol· October 2020

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Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels.
Qianqian Zhang, Zexi Cai, Marie Lhomme, Goutam Sahana, Philippe Lesnik

Sci Rep· October 2020

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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.
Sophie Tran, Ines Baba, Lucie Poupel, Sébastien Dussaud, Martine Moreau, Philippe Lesnik

Immunity· September 2020

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Gut Microbiome and Space Travelers' Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions.
Silvia Turroni, Marciane Magnani, Pukar Kc, Philippe Lesnik, Hubert Vidal

Front Physiol· September 2020

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Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Amine Toubal, Badr Kiaf, Lucie Beaudoin, Lucie Cagninacci, Moez Rhimi, Philippe Lesnik

Nat Commun· July 2020

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Exploring the Bacterial Impact on Cholesterol Cycle: A Numerical Study.
Mélanie Bourgin, Simon Labarthe, Aicha Kriaa, Marie Lhomme, Philippe Gérard, Philippe Lesnik

Front Microbiol· June 2020

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