Publications by authors named "Phillip A Sharp"

Claim this Profile
E
Engineered prime editors with minimal genomic errors.
Vikash P Chauhan, Phillip A Sharp, Robert Langer

Nature· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer.
Dig B Mahat, Heena Kumra, Sarah A Castro, Emily Metcalf, Kim Nguyen, Phillip A Sharp

Immunity· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA Dynamics Regulate Transcriptional Condensate Vivacity to Drive Gene Coordination.
Koichi Ogami, Ming M Zheng, Seiko Yoshino, Yohei Sugimoto, Mayu Seida, Phillip A Sharp

bioRxiv· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The future of open research policy should be evidence based.
Phillip A Sharp, William B Bonvillian, Amy Brand, David Goldston, Michael Stebbins

Proc Natl Acad Sci U S A· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Engineered prime editors with minimal genomic errors.
Vikash P Chauhan, Phillip A Sharp, Robert Langer

bioRxiv· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer.
Dig B Mahat, Heena Kumra, Sarah A Castro, Emily Metcalf, Kim Nguyen, Phillip A Sharp

bioRxiv· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single-cell nascent RNA sequencing unveils coordinated global transcription.
Dig B Mahat, Nathaniel D Tippens, Jorge D Martin-Rufino, Sean K Waterton, Jiayu Fu, Phillip A Sharp

Nature· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing.
Kavi Gupta, Chenxi Yang, Kayla McCue, Osbert Bastani, Phillip A Sharp

Genome Biol· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction for Song et al., "Sustained Small Interfering RNA-Mediated Human Immunodeficiency Virus Type 1 Inhibition in Primary Macrophages".
Erwei Song, Sang-Kyung Lee, Derek M Dykxhoorn, Carl Novina, Dong Zhang, Phillip A Sharp

J Virol· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription.
Dig B Mahat, Nathaniel D Tippens, Jorge D Martin-Rufino, Sean K Waterton, Jiayu Fu, Phillip A Sharp

bioRxiv· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oncogenic mutations impede nuclear RNA surveillance.
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Phillip A Sharp

Science· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Altered DNA repair pathway engagement by engineered CRISPR-Cas9 nucleases.
Vikash P Chauhan, Phillip A Sharp, Robert Langer

Proc Natl Acad Sci U S A· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcription factor antagonism regulates heterogeneity in embryonic stem cell states.
Sofia Hu, Emily Metcalf, Dig Bijay Mahat, Lynette Chan, Noor Sohal, Phillip A Sharp

Mol Cell· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA in formation and regulation of transcriptional condensates.
Phillip A Sharp, Arup K Chakraborty, Jonathan E Henninger, Richard A Young

RNA· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA-Mediated Feedback Control of Transcriptional Condensates.
Jonathan E Henninger, Ozgur Oksuz, Krishna Shrinivas, Ido Sagi, Gary LeRoy, Phillip A Sharp

Cell· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Partitioning of cancer therapeutics in nuclear condensates.
Isaac A Klein, Ann Boija, Lena K Afeyan, Susana Wilson Hawken, Mengyang Fan, Phillip A Sharp

Science· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons.
Amanda J Whipple, Vincent Breton-Provencher, Hannah N Jacobs, Udbhav K Chitta, Mriganka Sur, Phillip A Sharp

Mol Cell· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MicroRNAs organize intrinsic variation into stem cell states.
Meenakshi Chakraborty, Sofia Hu, Erica Visness, Marco Del Giudice, Andrea De Martino, Phillip A Sharp

Proc Natl Acad Sci U S A· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A.
Timothy J Kelly, Hiroshi I Suzuki, Jesse R Zamudio, Megumu Suzuki, Phillip A Sharp

RNA· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates.
Yang Eric Guo, John C Manteiga, Jonathan E Henninger, Benjamin R Sabari, Alessandra Dall'Agnese, Phillip A Sharp

Nature· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhancer Features that Drive Formation of Transcriptional Condensates.
Krishna Shrinivas, Benjamin R Sabari, Eliot L Coffey, Isaac A Klein, Ann Boija, Phillip A Sharp

Mol Cell· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gain-of-function mutation of microRNA-140 in human skeletal dysplasia.
Giedre Grigelioniene, Hiroshi I Suzuki, Fulya Taylan, Fatemeh Mirzamohammadi, Zvi U Borochowitz, Phillip A Sharp

Nat Med· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.
Sara J Dubbury, Paul L Boutz, Phillip A Sharp

Nature· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evolution of weak cooperative interactions for biological specificity.
Ang Gao, Krishna Shrinivas, Paul Lepeudry, Hiroshi I Suzuki, Phillip A Sharp

Proc Natl Acad Sci U S A· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Coactivator condensation at super-enhancers links phase separation and gene control.
Benjamin R Sabari, Alessandra Dall'Agnese, Ann Boija, Isaac A Klein, Eliot L Coffey, Phillip A Sharp

Science· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis