Publications by authors named "Pierre Painsec"

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PLK1 Inhibitor Onvansertib Enhances the Efficacy of Alpelisib in -Mutated HR-Positive Breast Cancer Resistant to Palbociclib and Endocrine Therapy: Preclinical Insights.
Sreeja Sreekumar, Elodie Montaudon, Davis Klein, Migdalia E Gonzalez, Pierre Painsec

Cancers (Basel)· September 2024

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Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers.
Arany Soosainathan, Marjan Iravani, Rania El-Botty, John Alexander, Laura Sourd, Pierre Painsec

Cancer Res· January 2024

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Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers.
Rania El-Botty, Ludivine Morriset, Elodie Montaudon, Zakia Tariq, Anne Schnitzler, Pierre Painsec

Nat Commun· July 2023

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Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts.
Florence Coussy, Marion Lavigne, Leanne de Koning, Rania El Botty, Fariba Nemati, Pierre Painsec

Theranostics· April 2021

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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance.
Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Pierre Painsec

Nat Commun· August 2020

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BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers.
Florence Coussy, Rania El-Botty, Sophie Château-Joubert, Ahmed Dahmani, Elodie Montaudon, Pierre Painsec

Sci Transl Med· February 2020

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A large collection of integrated genomically characterized patient-derived xenografts highlighting the heterogeneity of triple-negative breast cancer.
Florence Coussy, Leanne de Koning, Marion Lavigne, Virginie Bernard, Berengere Ouine, Pierre Painsec

Int J Cancer· October 2019

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