Publications by authors named "Pingwei Li"

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STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor.
Bao-Cun Zhang, Alice Pedersen, Line S Reinert, Ying Li, Ryo Narita, Lili Hu, Sirui Li, Muyesier Maimaitili, Zongliang Gao, Linda Henneman, Pingwei Li

Nat Immunol· November 2025

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Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon.
Lei Wu, Ya Yan, Ye Yuan, Zhenchao Zhao, Weiyu Qu, Pingwei Li, Xin Li

mBio· April 2025

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Ascending aorta dilatation indicates obstructive sleep apnea in Chinese patients with cardiovascular disease.
Luwen Qiu, Pingwei Li, Zhaohui Ding, Jing Wang, Ning Huang

Sleep Breath· February 2025

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Assessing Causality Between Androgenetic Alopecia with Depression: A Bidirectional Mendelian Randomization Study.
Haiyang Li, Haibin Cai, Pingwei Li, Yibin Zeng, Yao Zhang

Clin Cosmet Investig Dermatol· February 2025

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Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Omkar Shinde, Joshua A Boyer, Stephanie Cambier, Jordyn J VanPortfliet, Xuewu Sui, Elizabeth G Viverette, A Phillip West, Pingwei Li

Immunity· January 2025

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Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation.
Minjie Li, Cheng Zhu, Ye Yuan, Xiangyu Huang, Lei Wu, Pingwei Li, Xin Li

iScience· November 2024

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Seneca Valley virus circumvents Gasdermin A-mediated inflammation by targeting the pore-formation domain for cleavage.
Hongyan Yin, Zhenchao Zhao, Ya Yan, Ye Yuan, Weiyu Qu, Pingwei Li, Xin Li

mBio· October 2024

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Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease.
Xiangyu Huang, Zhenchao Zhao, Cheng Zhu, Lvye Chai, Ya Yan, Minjie Li, Zheng Liu, Pingwei Li, Xin Li

PLoS Pathog· July 2024

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The molecular mechanism of dsDNA sensing through the cGAS-STING pathway.
Omkar Shinde, Pingwei Li

Adv Immunol· June 2024

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Structural Evaluations of a Selective Human STING Agonist and Its Use in Macrophage Immunotherapies.
Zhichao Tang, Junxing Zhao, Ying Li, Shallu Tomer, Manikandan Selvaraju, Pingwei Li

ACS Med Chem Lett· May 2024

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Pulmonary artery dilatation in different causes of pulmonary hypertension.
Qunying Xi, Zhihong Liu, Changming Xiong, Qin Luo, Zhihui Zhao, Pingwei Li

Pulm Circ· October 2023

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Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing.
Ya Yan, Lei Wu, Ye Yuan, Haiwei Wang, Hongyan Yin, Minjie Li, Ruiying Liang, Yanjie Liu, Pingwei Li, Xin Li

PLoS Pathog· September 2023

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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Yuanjiu Lei, Jordyn J VanPortfliet, Yi-Fan Chen, Joshua D Bryant, Ying Li, Olivia N Brahms, Pingwei Li, A Phillip West

Cell· July 2023

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Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING Variants.
Zhichao Tang, Junxing Zhao, Ying Li, Shallu Tomer, Manikandan Selvaraju, Pingwei Li

bioRxiv· July 2023

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A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease.
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Wenshe Ray Liu

ACS Chem Biol· March 2023

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A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals.
Yuying Ma, Kai S Yang, Zhi Zachary Geng, Yugendar R Alugubelli, Namir Shaabani, Pingwei Li, Wenshe Ray Liu

Eur J Med Chem· October 2022

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A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals.
Yugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, Namir Shaabani, Kaustav Khatua, Pingwei Li, Wenshe Ray Liu

Eur J Med Chem· October 2022

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Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus.
Iktae Kim, Alyssa Dubrow, Bryan Zuniga, Baoyu Zhao, Noah Sherer, Pingwei Li

Nat Commun· October 2022

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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.
Chi G Weindel, Eduardo L Martinez, Xiao Zhao, Cory J Mabry, Samantha L Bell, Jordyn J VanPortfliet, Allison R Wagner, Pingwei Li, A Phillip West

Cell· August 2022

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A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds.
Erol C Vatansever, Kai S Yang, Zhi Zachary Geng, Yuchen Qiao, Pingwei Li, Wenshe Ray Liu

J Mol Biol· April 2022

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Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B.
Mengqiu Jiang, Joonyoung Shin, Rudo Simeon, Jeng-Yih Chang, Ran Meng, Pingwei Li

PLoS Biol· March 2022

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Preparation of BSA-coated Au Nanoparticles Contrast Agent and Its Application in PETCT Imaging.
Jing Wei, Pingwei Li, Huai Zhang, Ronghua Zhu

Cell Mol Biol (Noisy-le-grand)· March 2022

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Clone Selection Artificial Intelligence Algorithm-Based Positron Emission Tomography-Computed Tomography Image Information Data Analysis for the Qualitative Diagnosis of Serous Cavity Effusion in Patients with Malignant Tumors.
Jing Wei, Pingwei Li, Huai Zhang, Ronghua Zhu

J Healthc Eng· January 2022

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The P3 - -Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors.
Yuying Ma, Kai S Yang, Zhi Zachary Geng, Yugendar R Alugubelli, Namir Shaabani, Pingwei Li, Wenshe Ray Liu

bioRxiv· December 2021

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The -Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors.
Yugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, Namir Shaabani, Kaustav Khatua, Pingwei Li, Wenshe Ray Liu

bioRxiv· December 2021

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