Publications by authors named "Plinio Perrone"

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The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479).
Christopher McGuigan, Mary Rose Kelleher, Plinio Perrone, Sinead Mulready, Giovanna Luoni

Bioorg Med Chem Lett· August 2009

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The phosphoramidate ProTide approach greatly enhances the activity of beta-2'-C-methylguanosine against hepatitis C virus.
Christopher McGuigan, Plinio Perrone, Karolina Madela, Johan Neyts

Bioorg Med Chem Lett· August 2009

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First example of phosphoramidate approach applied to a 4'-substituted purine nucleoside (4'-azidoadenosine): conversion of an inactive nucleoside to a submicromolar compound versus hepatitis C virus.
Plinio Perrone, Felice Daverio, Rocco Valente, Sonal Rajyaguru, Joseph A Martin

J Med Chem· November 2007

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Application of the phosphoramidate ProTide approach to 4'-azidouridine confers sub-micromolar potency versus hepatitis C virus on an inactive nucleoside.
Plinio Perrone, Giovanna M Luoni, Mary Rose Kelleher, Felice Daverio, Annette Angell

J Med Chem· April 2007

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