Publications by authors named "Pontus Forsell"

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Positive Allosteric Modulators of Trk Receptors for the Treatment of Alzheimer's Disease.
Pontus Forsell, Cristina Parrado Fernández, Boel Nilsson, Johan Sandin, Gunnar Nordvall

Pharmaceuticals (Basel)· July 2024

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Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling - a potential therapeutic concept?
Nather Madjid, Veronica Lidell, Gunnar Nordvall, Maria Lindskog, Sven-Ove Ögren, Pontus Forsell

Psychopharmacology (Berl)· August 2023

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Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease.
Cristina Parrado Fernandez, Sanja Juric, Maria Backlund, Märta Dahlström, Nather Madjid, Pontus Forsell

Int J Mol Sci· July 2023

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Neurotrophin-targeted therapeutics: A gateway to cognition and more?
Gunnar Nordvall, Pontus Forsell, Johan Sandin

Drug Discov Today· October 2022

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Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction.
Märta Dahlström, Nather Madjid, Gunnar Nordvall, Magnus M Halldin, Erika Vazquez-Juarez, Pontus Forsell

Cells· July 2021

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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling.
Luana Naia, Catarina M Pinho, Giacomo Dentoni, Jianping Liu, Nuno Santos Leal, Pontus Forsell

BMC Biol· March 2021

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Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons.
Märta Dahlström, Gunnar Nordvall, Erik Sundström, Elisabet Åkesson, Gunilla Tegerstedt, Pontus Forsell

Eur J Neurosci· November 2019

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N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase.
Benjamin Pelcman, Andrei Sanin, Peter Nilsson, Wesley Schaal, Kristofer Olofsson, Pontus Forsell

Bioorg Med Chem Lett· August 2015

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3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1.
Benjamin Pelcman, Andrei Sanin, Peter Nilsson, Kiyo No, Wesley Schaal, Pontus Forsell

Bioorg Med Chem Lett· August 2015

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The battle of Alzheimer's Disease - the beginning of the future Unleashing the potential of academic discoveries.
Johan Lundkvist, Magnus M Halldin, Johan Sandin, Gunnar Nordvall, Pontus Forsell

Front Pharmacol· May 2014

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The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signaling.
Pontus Forsell, Helena Almqvist, Per Hillertz, Tomas Akerud, Magdalena Otrocka

J Biomol Screen· July 2013

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Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases.
Pontus K A Forsell, Asa Brunnström, Malin Johannesson, Hans-Erik Claesson

Lipids· August 2012

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Epigenetic and transcriptional control of the 15-lipoxygenase-1 gene in a Hodgkin lymphoma cell line.
Cheng Liu, Frida Schain, Hongya Han, Dawei Xu, Hillevi Andersson-Sand, Pontus Forsell

Exp Cell Res· February 2012

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Development of a fluorescent intensity assay amenable for high-throughput screening for determining 15-lipoxygenase activity.
Märta Dahlström, Daniel Forsström, Malin Johannesson, Yasmin Huque-Andersson, Marie Björk, Pontus K A Forsell

J Biomol Screen· July 2010

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Applicability of the triad concept for the positional specificity of mammalian lipoxygenases.
Robert Vogel, Christian Jansen, Jana Roffeis, Pallu Reddanna, Pontus Forsell

J Biol Chem· February 2010

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The expression of cytosolic phospholipase A2 and biosynthesis of leukotriene B4 in acute myeloid leukemia cells.
Gudmundur Runarsson, Stina Feltenmark, Pontus K A Forsell, Jan Sjöberg, Magnus Björkholm

Eur J Haematol· December 2007

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Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Salvatore C Ruffolo, Pontus K A Forsell, Xiling Yuan, Sylvie Desmarais, Jean Himms-Hagen

J Biol Chem· October 2007

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Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity.
Erik Andersson, Frida Schain, Märta Svedling, Hans-Erik Claesson, Pontus K A Forsell

Biochim Biophys Acta· December 2006

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Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-alpha.
Pontus K A Forsell, Anders O Olsson, Erik Andersson, Laxman Nallan, Michael H Gelb

Biochem Pharmacol· December 2005

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Transcriptional regulation of 15-lipoxygenase expression by promoter methylation.
Cheng Liu, Dawei Xu, Jan Sjöberg, Pontus Forsell, Magnus Björkholm

Exp Cell Res· July 2004

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