Publications by authors named "Maria Backlund"

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Survival and growth of saprotrophic and mycorrhizal fungi in recalcitrant amine, amide and ammonium containing media.
Åke Stenholm, Anders Backlund, Sara Holmström, Maria Backlund, Mikael Hedeland

PLoS One· July 2024

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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.
Douglas L Huseby, Sha Cao, Edouard Zamaratski, Sanjeewani Sooriyaarachchi, Shabbir Ahmad, Maria Backlund

Proc Natl Acad Sci U S A· April 2024

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N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands.
Johan Wannberg, Johan Gising, Martin Henriksson, Duc Duy Vo, Jonas Sävmarker, Maria Backlund

Eur J Med Chem· February 2024

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Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease.
Cristina Parrado Fernandez, Sanja Juric, Maria Backlund, Märta Dahlström, Nather Madjid

Int J Mol Sci· July 2023

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Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.
Jürgen Brem, Tharindi Panduwawala, Jon Ulf Hansen, Joanne Hewitt, Edgars Liepins, Maria Backlund

Nat Chem· January 2022

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Model-Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin.
Tomás Sou, Jon Hansen, Edgars Liepinsh, Maria Backlund, Onur Ercan

Clin Pharmacol Ther· April 2021

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N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands.
Johan Wannberg, Johan Gising, Jens Lindman, Jessica Salander, Hugo Gutiérrez-de-Terán, Maria Backlund

Bioorg Med Chem· January 2021

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A Series of Analogues to the ATR Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode.
Rebecka Isaksson, Jens Lindman, Johan Wannberg, Jessica Sallander, Maria Backlund

ChemistryOpen· January 2019

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Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5.
Matteo Rossi Sebastiano, Bradley C Doak, Maria Backlund, Vasanthanathan Poongavanam, Björn Over

J Med Chem· May 2018

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A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.
Johan Wannberg, Rebecka Isaksson, Ulf Bremberg, Maria Backlund, Jonas Sävmarker

Bioorg Med Chem Lett· February 2018

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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.
Maria Karlgren, Ivailo Simoff, Maria Backlund, Christine Wegler, Markus Keiser

J Pharm Sci· September 2017

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Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.
Ivailo Simoff, Maria Karlgren, Maria Backlund, Anne-Christine Lindström, Fabienne Z Gaugaz

J Pharm Sci· February 2016

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The aryl hydrocarbon receptor (AHR), a novel regulator of human melanogenesis.
Sandra Luecke, Maria Backlund, Bettina Jux, Charlotte Esser, Jean Krutmann

Pigment Cell Melanoma Res· December 2010

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Regulation of aryl hydrocarbon receptor signal transduction by protein tyrosine kinases.
Maria Backlund, Magnus Ingelman-Sundberg

Cell Signal· January 2005

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Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1.
Maria Karlgren, Maria Backlund, Inger Johansson, Mikael Oscarson, Magnus Ingelman-Sundberg

Biochem Biophys Res Commun· March 2004

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Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation.
Maria Backlund, Magnus Ingelman-Sundberg

Mol Pharmacol· February 2004

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Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29.
Ernest Sargsyan, Mikhail Baryshev, Maria Backlund, Anatoly Sharipo, Souren Mkrtchian

Gene· February 2002

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