Publications by authors named "Markus Keiser"

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Gene Expression and Protein Abundance of Nuclear Receptors in Human Intestine and Liver: A New Application for Mass Spectrometry-Based Targeted Proteomics.
Christoph Wenzel, Lisa Gödtke, Anne Reichstein, Markus Keiser, Diana Busch

Molecules· July 2022

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Expression and Functional Contribution of Different Organic Cation Transporters to the Cellular Uptake of Doxorubicin into Human Breast Cancer and Cardiac Tissue.
Marcus Otter, Susanne Csader, Markus Keiser, Stefan Oswald

Int J Mol Sci· December 2021

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Targeting OCT3 attenuates doxorubicin-induced cardiac injury.
Kevin M Huang, Megan Zavorka Thomas, Tarek Magdy, Eric D Eisenmann, Muhammad Erfan Uddin, Markus Keiser

Proc Natl Acad Sci U S A· February 2021

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Novel 3D organotypic urothelial cell culture model for identification of new therapeutic approaches in urological infections.
Laila Schneidewind, Thomas Neumann, Andrzej Plis, Sascha Brückmann, Markus Keiser

J Clin Virol· March 2020

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Affinity of Ketamine to Clinically Relevant Transporters.
Markus Keiser, Mahmoud Hasan, Stefan Oswald

Mol Pharm· January 2018

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The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.
Markus Keiser, Lars Kaltheuner, Charlotte Wildberg, Janett Müller, Markus Grube

J Pharm Sci· September 2017

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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.
Maria Karlgren, Ivailo Simoff, Maria Backlund, Christine Wegler, Markus Keiser

J Pharm Sci· September 2017

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The Ussing Chamber Assay to Study Drug Metabolism and Transport in the Human Intestine.
Beatrice Kisser, Eva Mangelsen, Caroline Wingolf, Lars Ivo Partecke, Claus-Dieter Heidecke, Markus Keiser

Curr Protoc Pharmacol· June 2017

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Effects of frequently used pharmaceutical excipients on the organic cation transporters 1-3 and peptide transporters 1/2 stably expressed in MDCKII cells.
Marcus Otter, Stefan Oswald, Werner Siegmund, Markus Keiser

Eur J Pharm Biopharm· March 2017

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Expression, regulation and function of intestinal drug transporters: an update.
Janett Müller, Markus Keiser, Marek Drozdzik, Stefan Oswald

Biol Chem· February 2017

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Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy.
Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K Kroemer

Drug Metab Dispos· October 2016

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Pharmacokinetics and Pulmonary Distribution of Clarithromycin and Rifampicin after Concomitant and Consecutive Administration in Foals.
Sarah Berlin, Lena Spieckermann, Stefan Oswald, Markus Keiser, Stefan Lumpe

Mol Pharm· March 2016

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The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
Shingen Misaka, Jana Knop, Katrin Singer, Eva Hoier, Markus Keiser

Mol Pharm· February 2016

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Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.
Werner Siegmund, Christiane Modess, Eberhard Scheuch, Karen Methling, Markus Keiser

Br J Clin Pharmacol· March 2015

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Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics.
Maria Bexten, Stefan Oswald, Markus Grube, Jia Jia, Tanja Graf, Markus Keiser

Mol Pharm· January 2015

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Characterization of the intestinal and hepatic uptake/efflux transport of the magnetic resonance imaging contrast agent gadolinium-ethoxylbenzyl-diethylenetriamine-pentaacetic acid.
Jia Jia, Dorothee Puls, Stefan Oswald, Gabriele Jedlitschky, Jens P Kühn, Markus Keiser

Invest Radiol· February 2014

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OATP1B3 is expressed in pancreatic β-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide.
Henriette E Meyer Zu Schwabedissen, Kerstin Boettcher, Tobias Steiner, Ute I Schwarz, Markus Keiser

Diabetes· February 2014

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Response.
Ali Nassif, Werner Siegmund, Markus Keiser, Werner Weitschies, Jens-Peter Kühn

Radiology· April 2013

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Steroid hormones specifically modify the activity of organic anion transporting polypeptides.
Anna Koenen, Kathleen Köck, Markus Keiser, Werner Siegmund, Heyo K Kroemer

Eur J Pharm Sci· November 2012

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Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
Ali Nassif, Jia Jia, Markus Keiser, Stefan Oswald, Christiane Modess

Radiology· September 2012

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Pharmaceutical excipients influence the function of human uptake transporting proteins.
Anett Engel, Stefan Oswald, Werner Siegmund, Markus Keiser

Mol Pharm· September 2012

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A LC-MS/MS method to evaluate the hepatic uptake of the liver-specific magnetic resonance imaging contrast agent gadoxetate (Gd-EOB-DTPA) in vitro and in humans.
Jia Jia, Markus Keiser, Ali Nassif, Werner Siegmund, Stefan Oswald

J Chromatogr B Analyt Technol Biomed Life Sci· April 2012

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Role of organic anion-transporting polypeptides for cellular mesalazine (5-aminosalicylic acid) uptake.
Jörg König, Hartmut Glaeser, Markus Keiser, Kathrin Mandery, Ulrich Klotz

Drug Metab Dispos· June 2011

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Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.
Kathrin Mandery, Krystyna Bujok, Ingrid Schmidt, Markus Keiser, Werner Siegmund

Biochem Pharmacol· December 2010

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A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV.
Katia Maalouf, Jia Jia, Sandra Rizk, Graham Brogden, Markus Keiser

J Inherit Metab Dis· August 2010

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