Publications by authors named "Quentin Bickle"

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The discovery of a novel series of compounds with single-dose efficacy against juvenile and adult Schistosoma species.
J Mark F Gardner, Nuha R Mansour, Andrew S Bell, Helena Helmby, Quentin Bickle

PLoS Negl Trop Dis· July 2021

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Antiprotozoal and antihelminthic properties of plants ingested by wild Japanese macaques (Macaca fuscata yakui) in Yakushima Island.
Deniz Tasdemir, Andrew J J MacIntosh, Polyxeni Stergiou, Marcel Kaiser, Nuha R Mansour, Quentin Bickle

J Ethnopharmacol· January 2020

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Quentin Bickle

PLoS Pathog· July 2016

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High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni.
Nuha R Mansour, Ross Paveley, J Mark F Gardner, Andrew S Bell, Tanya Parkinson, Quentin Bickle

PLoS Negl Trop Dis· April 2016

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Application of RNAi to Genomic Drug Target Validation in Schistosomes.
Alessandra Guidi, Nuha R Mansour, Ross A Paveley, Ian M Carruthers, Jérémy Besnard, Quentin D Bickle

PLoS Negl Trop Dis· May 2015

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Orally active antischistosomal early leads identified from the open access malaria box.
Katrin Ingram-Sieber, Noemi Cowan, Gordana Panic, Mireille Vargas, Nuha R Mansour, Quentin D Bickle

PLoS Negl Trop Dis· September 2014

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Do shoes reduce hookworm infection in school-aged children on Pemba Island, Zanzibar? A pragmatic trial.
Chris Bird, Shaali Ame, Marco Albonico, Quentin Bickle

Trans R Soc Trop Med Hyg· May 2014

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Performance and safety of praziquantel for treatment of intestinal schistosomiasis in infants and preschool children.
José C Sousa-Figueiredo, Martha Betson, Aaron Atuhaire, Moses Arinaitwe, Annalan M D Navaratnam, Quentin Bickle

PLoS Negl Trop Dis· March 2013

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Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases.
Ross A Paveley, Nuha R Mansour, Irene Hallyburton, Leo S Bleicher, Alex E Benn, Quentin D Bickle

PLoS Negl Trop Dis· November 2012

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Integrated dataset of screening hits against multiple neglected disease pathogens.
Solomon Nwaka, Dominique Besson, Bernadette Ramirez, Louis Maes, An Matheeussen, Quentin Bickle

PLoS Negl Trop Dis· December 2011

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Soil-transmitted helminthiasis in rural south-west China: prevalence, intensity and risk factor analysis.
Layla S Mofid, Quentin Bickle, Jin-Yong Jiang, Zun-Wei Du, Edward Patrick

Southeast Asian J Trop Med Public Health· May 2011

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Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune response.
Rommy Teran, Edward Mitre, Maritza Vaca, Silvia Erazo, Gisela Oviedo, Quentin Bickle

Clin Immunol· March 2011

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Comparison of microscopy and Alamar blue reduction in a larval based assay for schistosome drug screening.
Nuha R Mansour, Quentin D Bickle

PLoS Negl Trop Dis· August 2010

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Praziquantel analogs with activity against juvenile Schistosoma mansoni.
Yuxiang Dong, Jacques Chollet, Mireille Vargas, Nuha R Mansour, Quentin Bickle

Bioorg Med Chem Lett· April 2010

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Early exposure of infants to GI nematodes induces Th2 dominant immune responses which are unaffected by periodic anthelminthic treatment.
Victoria J Wright, Shaali Makame Ame, Haji Said Haji, Rosemary E Weir, David Goodman, Quentin D Bickle

PLoS Negl Trop Dis· March 2010

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Early helminth infections are inversely related to anemia, malnutrition, and malaria and are not associated with inflammation in 6- to 23-month-old Zanzibari children.
Jacqueline K Kung'u, David Goodman, Hamad J Haji, Mahdi Ramsan, Victoria J Wright, Quentin D Bickle

Am J Trop Med Hyg· December 2009

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Adjusting for the acute phase response is essential to interpret iron status indicators among young Zanzibari children prone to chronic malaria and helminth infections.
Jacqueline K Kung'u, Victoria J Wright, Hamad J Haji, Mahdi Ramsan, David Goodman, Quentin D Bickle

J Nutr· November 2009

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Chronic intestinal nematode infection exacerbates experimental Schistosoma mansoni infection.
Quentin D Bickle, Julie Solum, Helena Helmby

Infect Immun· December 2008

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Meclonazepam analogues as potential new antihelmintic agents.
Aman Mahajan, Vipan Kumar, Nuha R N Mansour, Quentin Bickle, Kelly Chibale

Bioorg Med Chem Lett· April 2008

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Characterization of beta-tubulin genes in hookworms and investigation of resistance-associated mutations using real-time PCR.
Jan M Schwenkenbecher, Marco Albonico, Quentin Bickle, Ray M Kaplan

Mol Biochem Parasitol· December 2007

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Schistosomes: challenges in compound screening.
Bernadette Ramirez, Quentin Bickle, Fouad Yousif, Foluke Fakorede, Marie-Annick Mouries

Expert Opin Drug Discov· October 2007

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A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infants.
David Goodman, Hamad J Haji, Quentin D Bickle, Rebecca J Stoltzfus, James M Tielsch

Am J Trop Med Hyg· April 2007

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Immune modulation by helminth infections.
Helena Helmby, Quentin Bickle

Parasite Immunol· October 2006

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The Schistosoma mansoni hepatic egg granuloma provides a favorable microenvironment for sustained growth of Leishmania donovani.
Mohammed F Hassan, Yaobi Zhang, Christian R Engwerda, Paul M Kaye, Hannah Sharp, Quentin D Bickle

Am J Pathol· September 2006

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Gastrointestinal nematode infection is associated with variation in innate immune responsiveness.
Joseph A Jackson, Joseph D Turner, Mahine Kamal, Victoria Wright, Quentin Bickle

Microbes Infect· February 2006

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