Publications by authors named "Jacques Chollet"

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Elimination of Schistosoma mansoni in infected mice by slow release of artemisone.
Daniel Gold, Mohammed Alian, Avraham Domb, Yara Karawani, Maysa Jbarien, Jacques Chollet

Int J Parasitol Drugs Drug Resist· August 2017

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Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).
Yuxiang Dong, Xiaofang Wang, Sriraghavan Kamaraj, Vivek J Bulbule, Francis C K Chiu, Jacques Chollet

J Med Chem· April 2017

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Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.
Xiaofang Wang, Yuxiang Dong, Sergio Wittlin, Susan A Charman, Francis C K Chiu, Jacques Chollet

J Med Chem· March 2013

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In vivo activity of aryl ozonides against Schistosoma species.
Jennifer Keiser, Katrin Ingram, Mireille Vargas, Jacques Chollet, Xiaofang Wang

Antimicrob Agents Chemother· February 2012

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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Susan A Charman, Sarah Arbe-Barnes, Ian C Bathurst, Reto Brun, Michael Campbell, Jacques Chollet

Proc Natl Acad Sci U S A· March 2011

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The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.
Yuxiang Dong, Kevin J McCullough, Sergio Wittlin, Jacques Chollet, Jonathan L Vennerstrom

Bioorg Med Chem Lett· November 2010

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Praziquantel analogs with activity against juvenile Schistosoma mansoni.
Yuxiang Dong, Jacques Chollet, Mireille Vargas, Nuha R Mansour, Quentin Bickle

Bioorg Med Chem Lett· April 2010

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Mefloquine--an aminoalcohol with promising antischistosomal properties in mice.
Jennifer Keiser, Jacques Chollet, Shu-Hua Xiao, Jin-Yan Mei, Pei-Ying Jiao

PLoS Negl Trop Dis· March 2010

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The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
Yuxiang Dong, Sergio Wittlin, Kamaraj Sriraghavan, Jacques Chollet, Susan A Charman

J Med Chem· January 2010

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The comparative antimalarial properties of weak base and neutral synthetic ozonides.
Yuanqing Tang, Sergio Wittlin, Susan A Charman, Jacques Chollet, Francis C K Chiu

Bioorg Med Chem Lett· January 2010

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Effect of single-dose oral mefloquine on the morphology of adult Schistosoma japonicum in mice.
Shu-Hua Xiao, Jacques Chollet, Jürg Utzinger, Jin-Yan Mei, Pei-Yin Jiao

Parasitol Res· September 2009

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Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity.
Xiaofang Wang, Darren J Creek, Charles E Schiaffo, Yuxiang Dong, Jacques Chollet

Bioorg Med Chem Lett· August 2009

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Histopathological changes in adult Schistosoma japonicum harbored in mice treated with a single dose of mefloquine.
Chao-Wei Zhang, Shu-Hua Xiao, Jürg Utzinger, Jacques Chollet, Jennifer Keiser

Parasitol Res· June 2009

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Malaria-infected mice are cured by oral administration of new artemisinin derivatives.
Gary H Posner, Wonsuk Chang, Lindsey Hess, Lauren Woodard, Sandra Sinishtaj, Jacques Chollet

J Med Chem· February 2008

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Spiro- and dispiro-1,2-dioxolanes: contribution of iron(II)-mediated one-electron vs two-electron reduction to the activity of antimalarial peroxides.
Xiaofang Wang, Yuxiang Dong, Sergio Wittlin, Darren Creek, Jacques Chollet

J Med Chem· November 2007

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Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers).
Yuxiang Dong, Darren Creek, Jacques Chollet, Hugues Matile, Susan A Charman

Antimicrob Agents Chemother· August 2007

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In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species.
Shu-Hua Xiao, Jennifer Keiser, Jacques Chollet, Jürg Utzinger, Yuxiang Dong

Antimicrob Agents Chemother· April 2007

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In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
Christopher Snyder, Jacques Chollet, Josefina Santo-Tomas, Christian Scheurer, Sergio Wittlin

Exp Parasitol· March 2007

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Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides.
Yuanqing Tang, Yuxiang Dong, Sergio Wittlin, Susan A Charman, Jacques Chollet

Bioorg Med Chem Lett· March 2007

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Evaluation of the in vivo activity of tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini.
Jennifer Keiser, Xiao Shu-Hua, Jacques Chollet, Marcel Tanner, Jürg Utzinger

Antimicrob Agents Chemother· March 2007

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Effect of artemether on the tegument of adult Schistosoma haematobium recovered from mice.
Shu-Hua Xiao, Marcel Tanner, Bing-Gui Shen, Jürg Utzinger, Jacques Chollet

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi· December 2006

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Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.
Maniyan Padmanilayam, Bernard Scorneaux, Yuxiang Dong, Jacques Chollet, Hugues Matile

Bioorg Med Chem Lett· November 2006

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Ultrastructural alterations of adult schistosoma haematobium harbored in mice following artemether administration.
Shu-ua Xiao, Jürg Utzinger, Bing-gui Shen, Marcel Tanner, Jacques Chollet

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi· October 2006

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Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes.
Yuxiang Dong, Yuanqing Tang, Jacques Chollet, Hugues Matile, Sergio Wittlin

Bioorg Med Chem· September 2006

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Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model.
Jennifer Keiser, Nadia Abou El Ela, Engy El Komy, Naglaa El Lakkany, Tarek Diab, Jacques Chollet

Am J Trop Med Hyg· August 2006

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