Publications by authors named "Hugues Matile"

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Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.
David M Shackleford, Francis C K Chiu, Kasiram Katneni, Scott Blundell, Jenna McLaren, Hugues Matile

ACS Infect Dis· July 2021

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Stochastic Protein Alkylation by Antimalarial Peroxides.
Joëlle Jourdan, Annabelle Walz, Hugues Matile, Alexander Schmidt, Jianbo Wu

ACS Infect Dis· December 2019

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Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit.
Ching-Ju Tsai, Jacopo Marino, Ricardo Adaixo, Filip Pamula, Jonas Muehle, Hugues Matile

Elife· June 2019

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Development of an antibody fragment that stabilizes GPCR/G-protein complexes.
Shoji Maeda, Antoine Koehl, Hugues Matile, Hongli Hu, Daniel Hilger

Nat Commun· September 2018

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Structure of the µ-opioid receptor-G protein complex.
Antoine Koehl, Hongli Hu, Shoji Maeda, Yan Zhang, Qianhui Qu, Hugues Matile

Nature· June 2018

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Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).
Yuxiang Dong, Xiaofang Wang, Sriraghavan Kamaraj, Vivek J Bulbule, Francis C K Chiu, Hugues Matile

J Med Chem· April 2017

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Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Paola Favuzza, Elena Guffart, Marco Tamborrini, Bianca Scherer, Anita M Dreyer, Hugues Matile

Elife· February 2017

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Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization.
Natalie Rose, Carlos Augusto Pinho-Nascimento, Alessia Ruggieri, Paola Favuzza, Marco Tamborrini, Hugues Matile

BMC Biotechnol· November 2016

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Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
Dominique Burger, Martine Stihle, Ashwani Sharma, Paola Di Lello, Jörg Benz, Hugues Matile

J Biol Chem· July 2016

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Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.
Matthias E Lauer, Alexandra Graff-Meyer, Arne C Rufer, Cyrille Maugeais, Elisabeth von der Mark, Hugues Matile

J Struct Biol· May 2016

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Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA.
Paola Favuzza, Simon Blaser, Anita M Dreyer, Guy Riccio, Marco Tamborrini, Hugues Matile

Malar J· March 2016

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Monoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel).
Joëlle Jourdan, Hugues Matile, Ellen Reift, Oliver Biehlmaier, Yuxiang Dong

ACS Infect Dis· January 2016

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Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.
Susanne Raab, Haiyan Wang, Sabine Uhles, Nadine Cole, Ruben Alvarez-Sanchez, Hugues Matile

Mol Metab· January 2016

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Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain.
Thomas Kremer, Ravi Jagasia, Annika Herrmann, Hugues Matile, Edilio Borroni

PLoS One· December 2013

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Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.
David W Banner, Bernard Gsell, Jörg Benz, Julian Bertschinger, Dominique Burger, Hugues Matile

Acta Crystallogr D Biol Crystallogr· June 2013

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Generation of an antibody toolbox to characterize hERG.
Georg J Hausammann, Thomas Heitkamp, Hugues Matile, Bernard Gsell, Ralf Thoma

Biochem Biophys Res Commun· February 2013

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Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen.
Anita M Dreyer, Hugues Matile, Petros Papastogiannidis, Jolanda Kamber, Paola Favuzza

J Immunol· June 2012

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Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism.
Ratna Karuna, Rebekka Park, Alaa Othman, Adriaan G Holleboom, Mohammad Mahdi Motazacker, Hugues Matile

Atherosclerosis· December 2011

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Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays.
Gregor Dernick, Stefan Obermüller, Cyrill Mangold, Christine Magg, Hugues Matile

J Lipid Res· December 2011

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Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.
Daria Esterházy, Ina Stützer, Haiyan Wang, Markus P Rechsteiner, Jeremy Beauchamp, Hugues Matile

Cell Metab· September 2011

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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Susan A Charman, Sarah Arbe-Barnes, Ian C Bathurst, Reto Brun, Michael Campbell, Hugues Matile

Proc Natl Acad Sci U S A· March 2011

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Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport.
Eric J Niesor, Christine Magg, Naoto Ogawa, Hiroshi Okamoto, Elisabeth von der Mark, Hugues Matile

J Lipid Res· December 2010

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An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells.
Anita M Dreyer, Jeremy Beauchamp, Hugues Matile, Gerd Pluschke

BMC Biotechnol· December 2010

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The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
Yuxiang Dong, Sergio Wittlin, Kamaraj Sriraghavan, Jacques Chollet, Susan A Charman, Hugues Matile

J Med Chem· January 2010

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The comparative antimalarial properties of weak base and neutral synthetic ozonides.
Yuanqing Tang, Sergio Wittlin, Susan A Charman, Jacques Chollet, Francis C K Chiu, Hugues Matile

Bioorg Med Chem Lett· January 2010

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