Publications by authors named "Quinn Lu"

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Biochemical and functional characterization of the p.A165T missense variant of mitochondrial amidoxime-reducing component 1.
Wangfang Hou, Christian Watson, Ted Cecconie, Menaka N Bolaki, Jennifer J Brady, Quinn Lu

J Biol Chem· June 2024

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Comparative Analysis of Multiple Immunoassays for Cytokine Profiling in Drug Discovery.
Michael Platchek, Quinn Lu, Hoang Tran, Wensheng Xie

SLAS Discov· December 2020

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Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays.
Xin Zeng, Robert Kirkpatrick, Glenn Hofmann, Didier Grillot, Valerie Linhart, Quinn Lu

PLoS One· April 2019

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Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments.
Michelle L Kimberland, Wangfang Hou, Adolfo Alfonso-Pecchio, Stephen Wilson, Yanhua Rao, Quinn Lu

J Biotechnol· October 2018

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Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan, Lluis Ballell, Quinn Lu

Nat Commun· July 2018

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A Luciferase Reporter Gene System for High-Throughput Screening of γ-Globin Gene Activators.
Wensheng Xie, Robert Silvers, Michael Ouellette, Zining Wu, Quinn Lu

Methods Mol Biol· December 2017

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Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan, Lluis Ballell, Quinn Lu

Nat Commun· July 2017

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Applications of CRISPR genome editing technology in drug target identification and validation.
Quinn Lu, George P Livi, Sundip Modha, Kosuke Yusa, Ricardo Macarrón

Expert Opin Drug Discov· June 2017

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress.
Pu Qin, Pelin Arabacilar, Roberta E Bernard, Weike Bao, Alan R Olzinski, Quinn Lu

J Am Heart Assoc· May 2017

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Gene Expression in Mammalian Cells Using BacMam, a Modified Baculovirus System.
James A Fornwald, Quinn Lu, Frederick M Boyce, Robert S Ames

Methods Mol Biol· October 2016

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A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance.
Xin Zeng, Monica Montoute, Tiger W Bee, Hong Lin, Lorena A Kallal, Quinn Lu

J Biomol Screen· March 2016

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Co-expression for intracellular processing in microbial protein production.
Quinn Lu, Juan C Aon

Biotechnol Lett· March 2014

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Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
Basil P Hubbard, Christine Loh, Ana P Gomes, Jun Li, Quinn Lu

Cell Cycle· July 2013

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Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase.
Reema K Thalji, Jeff J McAtee, Svetlana Belyanskaya, Martin Brandt, Gregory D Brown, Quinn Lu

Bioorg Med Chem Lett· June 2013

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Development of a cell-based high throughput luciferase enzyme fragment complementation assay to identify nuclear-factor-e2-related transcription factor 2 activators.
Wensheng Xie, Christina Pao, Taylor Graham, Ed Dul, Quinn Lu

Assay Drug Dev Technol· December 2012

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Perspectives on the discovery of small-molecule modulators for epigenetic processes.
Quinn Lu, Amy M Quinn, Mehul P Patel, Simon F Semus, Alan P Graves

J Biomol Screen· June 2012

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Production of protein complexes via co-expression.
John J Kerrigan, Qing Xie, Robert S Ames, Quinn Lu

Protein Expr Purif· January 2011

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Development of a high throughput cell-based assay for soluble epoxide hydrolase using BacMam technology.
Wensheng Xie, Xiaoyan Tang, Quinn Lu, Robert S Ames, Steven J Ratcliffe

Mol Biotechnol· July 2010

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Optimized procedures for producing biologically active chemokines.
Quinn Lu, Matthew C Burns, Patrick J McDevitt, Taylor L Graham, Abby J Sukman

Protein Expr Purif· June 2009

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Evidence for allosteric interactions of antagonist binding to the smoothened receptor.
Cynthia M Rominger, Wei-Lin Tiger Bee, Robert A Copeland, Elizabeth A Davenport, Aidan Gilmartin, Quinn Lu

J Pharmacol Exp Ther· June 2009

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Viral-mediated gene delivery for cell-based assays in drug discovery.
Robert S Ames, Quinn Lu

Expert Opin Drug Discov· March 2009

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Frameshift events associated with the lysyl-tRNA and the rare arginine codon, AGA, in Escherichia coli: a case study involving the human Relaxin 2 protein.
John J Kerrigan, Dean E McNulty, Matthew Burns, Kimberly E Allen, Xiaoyan Tang, Quinn Lu

Protein Expr Purif· August 2008

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Development of a high-throughput cell-based assay for 11beta-hydroxysteroid dehydrogenase type 1 using BacMam technology.
Da-Yuan Wang, Quinn Lu, Stacey L Walsh, Lisa Payne, Sundip S Modha

Mol Biotechnol· June 2008

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Suppressing posttranslational gluconoylation of heterologous proteins by metabolic engineering of Escherichia coli.
Juan C Aon, Richard J Caimi, Alexander H Taylor, Quinn Lu, Femi Oluboyede

Appl Environ Microbiol· February 2008

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Gene expression in mammalian cells using BacMam, a modified baculovirus system.
James A Fornwald, Quinn Lu, Dayuan Wang, Robert S Ames

Methods Mol Biol· November 2007

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