Publications by authors named "R H Heflich"

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Assessing carcinogenic outcomes following short-term exposure to potentially DNA-reactive drugs: Are available data sufficient to inform risk assessment?
Dayton M Petibone, Jennifer M Shemansky, Timothy W Robison, Aisar H Atrakchi, Robert H Heflich

Regul Toxicol Pharmacol· February 2026

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Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models.
Ji-Eun Seo, Hannah Xu, Xilin Li, Aisar H Atrakchi, Timothy McGovern, Robert H Heflich

Regul Toxicol Pharmacol· November 2025

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Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen.
Xiaoqing Guo, Ji-Eun Seo, Jaime Miranda-Colon, Hannah Xu, Javier Revollo, Robert H Heflich

J Environ Sci Health C Toxicol Carcinog· November 2025

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Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Daishiro Miura, Robert H Heflich

Methods Mol Biol· November 2025

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N-nitroso-ethylisopropylamine mutagenicity in rat liver using the cII transgenic mutation assay and duplex sequencing analysis of genomic DNA.
Li Xia, Jian Yan, Ying Chen, Kamela Mitchell, Timothy J McGovern, Robert H Heflich

Chem Biol Interact· September 2025

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