Publications by authors named "Rachel Abbotts"

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ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushelendra Tripathi, Collin M Coon, Saranya Rajendran

Cancer Res· April 2025

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ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushlendra Tripathi, Collin M Coon, Saranya Rajendran

bioRxiv· October 2024

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Pharmacologic Induction of BRCAness in -Proficient Cancers: Expanding PARP Inhibitor Use.
Rachel Abbotts, Anna J Dellomo, Feyruz V Rassool

Cancers (Basel)· May 2022

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PARP1 PARylates and stabilizes STAT5 in FLT3-ITD acute myeloid leukemia and other STAT5-activated cancers.
Anna J Dellomo, Rachel Abbotts, Christian L Eberly, Mariusz Karbowski, Maria R Baer

Transl Oncol· January 2022

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Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR.
Gemma Puts, Stuart Jarrett, Mary Leonard, Nicolette Matsangos, Devin Snyder, Rachel Abbotts

Int J Mol Sci· August 2020

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DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation.
Rachel Abbotts, Michael J Topper, Christopher Biondi, Daniel Fontaine, Reena Goswami

Proc Natl Acad Sci U S A· November 2019

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Coordination of DNA single strand break repair.
Rachel Abbotts, David M Wilson

Free Radic Biol Med· June 2017

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Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.
Tarek M A Abdel-Fatah, Roslin Russell, Nada Albarakati, David J Maloney, Dorjbal Dorjsuren, Rachel Abbotts

Mol Oncol· October 2014

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DNA repair in cancer: emerging targets for personalized therapy.
Rachel Abbotts, Nicola Thompson, Srinivasan Madhusudan

Cancer Manag Res· June 2014

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Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.
Rachel Abbotts, Rosalyn Jewell, Jérémie Nsengimana, David J Maloney, Anton Simeonov

Oncotarget· May 2014

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Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer?
Tarek Abdel-Fatah, Arvind Arora, Ipek Gorguc, Rachel Abbotts, Sarah Beebeejaun

Antioxid Redox Signal· June 2013

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Clinicopathological and functional significance of XRCC1 expression in ovarian cancer.
Tarek Abdel-Fatah, Rebeka Sultana, Rachel Abbotts, Claire Hawkes, Claire Seedhouse

Int J Cancer· June 2013

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Targeting XRCC1 deficiency in breast cancer for personalized therapy.
Rebeka Sultana, Tarek Abdel-Fatah, Rachel Abbotts, Claire Hawkes, Nada Albarakati

Cancer Res· March 2013

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Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors.
Rebeka Sultana, Daniel R McNeill, Rachel Abbotts, Mohammed Z Mohammed, Malgorzata Z Zdzienicka

Int J Cancer· November 2012

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Base excision repair factors are promising prognostic and predictive markers in cancer.
Lucy Gossage, Christina Perry, Rachel Abbotts, Srinivasan Madhusudan

Curr Mol Pharmacol· January 2012

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Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer.
Rachel Abbotts, Srinivasan Madhusudan

Cancer Treat Rev· August 2010

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