Publications by authors named "Rachel D Crouch"

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Biotransformation research advances - 2024 year in review.
Lionel Cheruzel, Upendra A Argikar, Pietro Brunetti, Maria Chatzopoulou, Sungjoon Cho, Rachel D Crouch

Drug Metab Rev· November 2025

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Discovery of VU0467319: an M Positive Allosteric Modulator Candidate That Advanced into Clinical Trials.
Michael S Poslunsey, Michael R Wood, Changho Han, Shaun R Stauffer, Joseph D Panarese, Rachel D Crouch

ACS Chem Neurosci· January 2025

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Bioactivation and reactivity research advances - 2023 year in review.
Shuai Wang, Upendra A Argikar, Maria Chatzopoulou, Sungjoon Cho, Rachel D Crouch

Drug Metab Rev· August 2024

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Bioactivation and reactivity research advances - 2022 year in review‡.
Shuai Wang, Upendra A Argikar, Lionel Cheruzel, Sungjoon Cho, Rachel D Crouch

Drug Metab Rev· November 2023

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Biotransformation research advances - 2022 year in review.
S Cyrus Khojasteh, Upendra A Argikar, Lionel Cheruzel, Sungjoon Cho, Rachel D Crouch

Drug Metab Rev· November 2023

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Mechanistic Investigation of the Time-Dependent Aldehyde Oxidase Inhibitor Hydralazine.
J Paige Barnes, Shaoyun M Yang, Taylor S Thompson, Caithlyne M Guevarra, Shaniya S Pleasant, Rachel D Crouch

Drug Metab Dispos· June 2023

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Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib.
Bethany D Latham, D Spencer Oskin, Rachel D Crouch, Matthew J Vergne, Klarissa D Jackson

Chem Res Toxicol· September 2022

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Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions.
Slobodan P Rendić, Rachel D Crouch, F Peter Guengerich

Arch Toxicol· August 2022

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Bioactivation and reactivity research advances - 2021 year in review.
Klarissa D Jackson, Upendra A Argikar, Sungjoon Cho, Rachel D Crouch, James P Driscoll

Drug Metab Rev· August 2022

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Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CL).
Sang Hoon Han, Christopher M Goins, Tarun Arya, Woo-Jin Shin, Joshua Maw, Rachel D Crouch

J Med Chem· February 2022

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Case Study 11: Considerations for Enzyme Mapping Experiments-Interaction Between the Aldehyde Oxidase Inhibitor Hydralazine and Glutathione.
Rachel D Crouch, Jessica L Beers, Klarissa D Jackson

Methods Mol Biol· August 2021

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Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation.
Jennifer E Bissada, Vivian Truong, Arsany A Abouda, Kahari J Wines, Rachel D Crouch

Drug Metab Dispos· November 2019

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A novel in vitro allometric scaling methodology for aldehyde oxidase substrates to enable selection of appropriate species for traditional allometry.
Rachel D Crouch, J Matthew Hutzler, J Scott Daniels

Xenobiotica· March 2018

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Species-Specific Involvement of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of the Pyrimidine-Containing mGlu-Negative Allosteric Modulator VU0424238 (Auglurant).
Rachel D Crouch, Anna L Blobaum, Andrew S Felts, P Jeffrey Conn, Craig W Lindsley

Drug Metab Dispos· December 2017

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Evaluating the Disposition of a Mixed Aldehyde Oxidase/Cytochrome P450 Substrate in Rats with Attenuated P450 Activity.
Rachel D Crouch, Ryan D Morrison, Frank W Byers, Craig W Lindsley, Kyle A Emmitte

Drug Metab Dispos· August 2016

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