Publications by authors named "Klarissa D Jackson"

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Evaluating cannabidiol-induced liver injury with and without valproate using a three-dimensional human hepatocyte spheroid model.
Jessica L Beers, Shalon L Harvey, Raeanne M Lanphier, Blake R Rushing, Susan L McRitchie, Klarissa D Jackson

Toxicol In Vitro· December 2025

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Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity.
Muluneh M Fashe, Jonghwa Lee, Joseph T Grieco, John K Fallon, Ian R Mulrenin, Klarissa D Jackson

Front Pharmacol· December 2025

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N-acetyltransferase (NAT) 1 and NAT2 enzyme activities drive interindividual variability in sulfamethoxazole N-acetylation.
Raeanne M Lanphier, Bethany D Latham, Amanda J Gerringer, Tyler Interrante, Corbin D Jones, Klarissa D Jackson

Drug Metab Dispos· November 2025

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Elucidating Molecular Mechanisms of Drug-Induced Hepatotoxicity of Lapatinib.
Qinying Yu, Li Ma, Leah M Norona, Peter S Dragovich, Jianshuang Wang, Klarissa D Jackson

J Med Chem· August 2025

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Impact of variation in CYP3A and CYP2C8 on tucatinib metabolic clearance in human liver microsomes.
Bethany D Latham, Pegah Montazeri, Licza F Lobo, John K Fallon, Klarissa D Jackson

Drug Metab Dispos· May 2025

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Wellness in the invisible workforce: a pilot well-being study in black, indigenous, and people of color (BIPOC) women faculty in the pharmacy and pharmaceutical sciences.
Suzanne C Harris, Matthew Shane Loop, Kaniz Afroz Tanni, Klarissa D Jackson, Carla Y White

BMC Med Educ· May 2025

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Impact of sex and pregnancy on hepatic CYP3A4 expression and activity in a humanized mouse model.
Muluneh M Fashe, Taryn A Miner, Valeria Laboy Collazo, Joseph T Grieco, John K Fallon, Klarissa D Jackson

Drug Metab Dispos· February 2025

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Interindividual variability in CYP3A-mediated venetoclax metabolism in vitro and in vivo in patients with chronic lymphocytic leukemia.
Jonghwa Lee, Jessica L Beers, Isabel Cheng, Vivian Truong, Zachary Brown, Klarissa D Jackson

Clin Transl Sci· December 2024

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Advances and Challenges in Modeling Cannabidiol Pharmacokinetics and Hepatotoxicity.
Jessica L Beers, Zhu Zhou, Klarissa D Jackson

Drug Metab Dispos· May 2024

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Kinase Inhibitors FDA Approved 2018-2023: Drug Targets, Metabolic Pathways, and Drug-Induced Toxicities.
Bethany D Latham, Raeanne M Geffert, Klarissa D Jackson

Drug Metab Dispos· May 2024

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CBD and THC in Special Populations: Pharmacokinetics and Drug-Drug Interactions.
Lixuan Qian, Jessica L Beers, Klarissa D Jackson, Zhu Zhou

Pharmaceutics· April 2024

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A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment.
Jonghwa Lee, Jessica L Beers, Raeanne M Geffert, Klarissa D Jackson

Biomolecules· January 2024

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WHO CAN USE YOUR CELLS OR TISSUES FOR SCIENTIFIC RESEARCH?
Jessica L Beers, Raeanne M Geffert, Bethany D Latham, Klarissa D Jackson

Front Young Minds· January 2024

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Biotransformation research advances - 2022 year in review.
S Cyrus Khojasteh, Upendra A Argikar, Lionel Cheruzel, Sungjoon Cho, Rachel D Crouch, Klarissa D Jackson

Drug Metab Rev· November 2023

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Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine.
Klarissa D Jackson, Brahim Achour, Jonghwa Lee, Raeanne M Geffert, Jessica L Beers

Drug Metab Dispos· October 2023

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Vaping additives cannabinoid oil and vitamin E acetate adhere to and damage the human airway epithelium.
Boris Reidel, Sabri Abdelwahab, Joe Alexander Wrennall, Phillip W Clapp, Jessica L Beers, Klarissa D Jackson

J Appl Toxicol· May 2023

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Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol.
Jessica L Beers, Aurora K Authement, Nina Isoherranen, Klarissa D Jackson

ACS Med Chem Lett· May 2023

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Verifying in vitro-determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically-based pharmacokinetic modeling.
Cindy H T Yeung, Jessica L Beers, Klarissa D Jackson, Andrea N Edginton

CPT Pharmacometrics Syst Pharmacol· March 2023

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Formation of CYP3A-specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β-hydroxycholesterol/cholesterol ratio.
Jonghwa Lee, John K Fallon, Philip C Smith, Klarissa D Jackson

Clin Transl Sci· February 2023

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Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib.
Bethany D Latham, D Spencer Oskin, Rachel D Crouch, Matthew J Vergne, Klarissa D Jackson

Chem Res Toxicol· September 2022

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Biotransformation novel advances - 2021 year in review.
S Cyrus Khojasteh, Upendra A Argikar, Sungjoon Cho, Rachel Crouch, Carley J S Heck, Klarissa D Jackson

Drug Metab Rev· August 2022

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Bioactivation and reactivity research advances - 2021 year in review.
Klarissa D Jackson, Upendra A Argikar, Sungjoon Cho, Rachel D Crouch, James P Driscoll

Drug Metab Rev· August 2022

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Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study.
Anjali Gupta, Veeral Saraiya, April Deveaux, Taofik Oyekunle, Klarissa D Jackson

Sci Rep· June 2022

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Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation.
Elizabeth A Burnham, Arsany A Abouda, Jennifer E Bissada, Dasean T Nardone-White, Jessica L Beers, Klarissa D Jackson

Chem Res Toxicol· May 2022

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Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol.
Jessica L Beers, Dong Fu, Klarissa D Jackson

Drug Metab Dispos· October 2021

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