Publications by authors named "Radu Dobrin"

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A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients.
Lauren A Peters, Joshua R Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Radu Dobrin

Commun Biol· January 2023

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Evolving use of real-world evidence in the regulatory process: a focus on immuno-oncology treatment and outcomes.
John C O'Donnell, T Kim Le, Radu Dobrin, Mitch Higashi, Ashley Pereira

Future Oncol· January 2021

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and mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort.
Simon Papillon-Cavanagh, Parul Doshi, Radu Dobrin, Joseph Szustakowski, Alice M Walsh

ESMO Open· April 2020

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High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease.
Antonio F Di Narzo, Carrie Brodmerkel, Shannon E Telesco, Carmen Argmann, Lauren A Peters, Radu Dobrin

J Crohns Colitis· March 2019

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A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Lauren A Peters, Jacqueline Perrigoue, Arthur Mortha, Alina Iuga, Won-Min Song, Radu Dobrin

Nat Genet· October 2017

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Integrating personalized gene expression profiles into predictive disease-associated gene pools.
Jörg Menche, Emre Guney, Amitabh Sharma, Patrick J Branigan, Matthew J Loza, Radu Dobrin

NPJ Syst Biol Appl· March 2017

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High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.
Antonio F Di Narzo, Shannon E Telesco, Carrie Brodmerkel, Carmen Argmann, Lauren A Peters, Radu Dobrin

PLoS Genet· January 2017

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Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci.
Antonio F Di Narzo, Lauren A Peters, Carmen Argmann, Aleksandar Stojmirovic, Jacqueline Perrigoue, Radu Dobrin

Clin Transl Gastroenterol· June 2016

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Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.
Qi Li, Cheng Hiang Lee, Lauren A Peters, Lucas A Mastropaolo, Cornelia Thoeni, Radu Dobrin

Gastroenterology· May 2016

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Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations.
Alice M Walsh, John W Whitaker, C Chris Huang, Yauheniya Cherkas, Sarah L Lamberth, Radu Dobrin

Genome Biol· April 2016

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NDEx, the Network Data Exchange.
Dexter Pratt, Jing Chen, David Welker, Ricardo Rivas, Rudolf Pillich, Radu Dobrin

Cell Syst· October 2015

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A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Amitabh Sharma, Jörg Menche, C Chris Huang, Tatiana Ort, Xiaobo Zhou, Radu Dobrin

Hum Mol Genet· June 2015

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Expression quantitative trait Loci acting across multiple tissues are enriched in inherited risk for coronary artery disease.
Hassan Foroughi Asl, Husain A Talukdar, Alida S D Kindt, Rajeev K Jain, Raili Ermel, Radu Dobrin

Circ Cardiovasc Genet· April 2015

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Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs.
Xiaoling Zhang, Hinco J Gierman, Daniel Levy, Andrew Plump, Radu Dobrin

BMC Genomics· June 2014

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Bin Zhang, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Radu Dobrin

Cell· April 2013

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Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients.
Mohammed Qatanani, Yejun Tan, Radu Dobrin, Danielle M Greenawalt, Guanghui Hu

Diabetes· March 2013

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Dissecting cis regulation of gene expression in human metabolic tissues.
Radu Dobrin, Danielle M Greenawalt, Guanghui Hu, Daniel M Kemp, Lee M Kaplan

PLoS One· December 2011

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The arrestin domain-containing 3 protein regulates body mass and energy expenditure.
Parth Patwari, Valur Emilsson, Eric E Schadt, William A Chutkow, Samuel Lee, Radu Dobrin

Cell Metab· November 2011

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A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort.
Danielle M Greenawalt, Radu Dobrin, Eugene Chudin, Ida J Hatoum, Christine Suver

Genome Res· July 2011

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Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
Hua Zhong, John Beaulaurier, Pek Yee Lum, Cliona Molony, Xia Yang, Radu Dobrin

PLoS Genet· May 2010

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Ppargamma2 is a key driver of longevity in the mouse.
Carmen Argmann, Radu Dobrin, Sami Heikkinen, Aurélie Auburtin, Laurent Pouilly

PLoS Genet· December 2009

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Common body mass index-associated variants confer risk of extreme obesity.
Chris Cotsapas, Elizabeth K Speliotes, Ida J Hatoum, Danielle M Greenawalt, Radu Dobrin

Hum Mol Genet· September 2009

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Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease.
Radu Dobrin, Jun Zhu, Cliona Molony, Carmen Argman, Mark L Parrish

Genome Biol· August 2009

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Dissecting self-renewal in stem cells with RNA interference.
Natalia Ivanova, Radu Dobrin, Rong Lu, Iulia Kotenko, John Levorse

Nature· August 2006

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Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network.
Radu Dobrin, Qasim K Beg, Albert-László Barabási, Zoltán N Oltvai

BMC Bioinformatics· January 2004

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