Publications by authors named "Rajitha Doddareddy"

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Technical Considerations of Pharmacokinetic Assays for LNP-mRNA Drug Products by RT-qPCR.
Jason Pennucci, Amanda Hays, Wendy Adamowicz, Mitra Azadeh, Mohamed Benhammadi, Rajitha Doddareddy

AAPS J· September 2025

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Recommendations for Method Development and Validation of qPCR and dPCR Assays in Support of Cell and Gene Therapy Drug Development.
Amanda Hays, Mark Wissel, Kelly Colletti, Russell Soon, Mitra Azadeh, Rajitha Doddareddy

AAPS J· February 2024

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Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment.
Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao

MAbs· November 2021

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Considerations in the development and validation of real-time quantitative polymerase chain reaction and its application in regulated bioanalysis to characterize the cellular kinetics of CAR-T products in clinical studies.
Tong-Yuan Yang, Rajitha Doddareddy

Bioanalysis· January 2021

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A generic method for the detection of polyethylene glycol specific IgG and IgM antibodies in human serum.
Christopher Ehlinger, Nathan Spear, Rajitha Doddareddy, Gopi Shankar, Allen Schantz

J Immunol Methods· November 2019

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Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice.
Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh

J Pharmacol Exp Ther· April 2018

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Deciphering the In Vivo Performance of a Monoclonal Antibody to Neutralize Its Soluble Target at the Site of Action in a Mouse Collagen-Induced Arthritis Model.
Weirong Wang, Thomas S McIntosh, Xiling Jiang, Rajitha Doddareddy, Elayne C Dell

Pharm Res· April 2016

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Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeys.
Weirong Wang, Xiaofeng Wang, Rajitha Doddareddy, Damien Fink, Thomas McIntosh

AAPS J· January 2014

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