Publications by authors named "Ralf Leonhardt"

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Position statement on genuine physiotherapy research at German university hospitals.
Susanne G R Klotz, Andrea Bökel, Maria Friderichs-Nedohibchenko, Isabelle Stickdorn, Barbara Vogel, Ralf Leonhardt

Ger Med Sci· June 2024

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Identification of critical amino acid residues in the regulatory N-terminal domain of PMEL.
Susan M Mitchell, Morven Graham, Xinran Liu, Ralf M Leonhardt

Sci Rep· April 2021

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Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma.
Adrian A Lahola-Chomiak, Tim Footz, Kim Nguyen-Phuoc, Gavin J Neil, Baojian Fan, Ralf M Leonhardt

Hum Mol Genet· April 2019

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Repeat domain-associated O-glycans govern PMEL fibrillar sheet architecture.
Morven Graham, Athanasia C Tzika, Susan M Mitchell, Xinran Liu, Ralf M Leonhardt

Sci Rep· April 2019

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Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen.
Nathalie Vigneron, Violette Ferrari, Benoît J Van den Eynde, Peter Cresswell, Ralf M Leonhardt

J Immunol· October 2018

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Xenophagic pathways and their bacterial subversion in cellular self-defense - παντα ρει - everything is in flux.
Nadine Radomski, Annica Rebbig, Ralf M Leonhardt, Michael R Knittler

Int J Med Microbiol· January 2018

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Melanosomal formation of PMEL core amyloid is driven by aromatic residues.
Jia Shee Hee, Susan M Mitchell, Xinran Liu, Ralf M Leonhardt

Sci Rep· March 2017

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Hydrophobic Interactions Are Key To Drive the Association of Tapasin with Peptide Transporter Subunit TAP2.
Elke Rufer, Danny Kägebein, Ralf M Leonhardt, Michael R Knittler

J Immunol· December 2015

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Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization.
Ralf M Leonhardt, Parwiz Abrahimi, Susan M Mitchell, Peter Cresswell

J Immunol· March 2014

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Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils.
Ralf M Leonhardt, Nathalie Vigneron, Jia Shee Hee, Morven Graham, Peter Cresswell

Mol Biol Cell· April 2013

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Dynamics of major histocompatibility complex class I association with the human peptide-loading complex.
Michaela S Panter, Ankur Jain, Ralf M Leonhardt, Taekjip Ha, Peter Cresswell

J Biol Chem· September 2012

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Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells.
Vincent Stroobant, Nathalie Demotte, Rosalie M Luiten, Ralf M Leonhardt, Peter Cresswell

Eur J Immunol· June 2012

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Cancer immunotherapy takes a multi-faceted approach to kick the immune system into gear.
Peniel M Dimberu, Ralf M Leonhardt

Yale J Biol Med· December 2011

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Identification of key amino acid residues that determine the ability of high risk HPV16-E7 to dysregulate major histocompatibility complex class I expression.
Corina Heller, Tanja Weisser, Antje Mueller-Schickert, Elke Rufer, Alexander Hoh, Ralf M Leonhardt

J Biol Chem· April 2011

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Proprotein convertases process Pmel17 during secretion.
Ralf M Leonhardt, Nathalie Vigneron, Christoph Rahner, Peter Cresswell

J Biol Chem· March 2011

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A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.
Wei Zhang, Pamela A Wearsch, Yajuan Zhu, Ralf M Leonhardt, Peter Cresswell

Proc Natl Acad Sci U S A· March 2011

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Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.
Ralf M Leonhardt, Nathalie Vigneron, Christoph Rahner, Benoît J Van den Eynde, Peter Cresswell

J Biol Chem· May 2010

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Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.
Ralf M Leonhardt, Dorothee Fiegl, Elke Rufer, Axel Karger, Barbara Bettin

J Immunol· March 2010

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Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation.
Nathalie Vigneron, David R Peaper, Ralf M Leonhardt, Peter Cresswell

Eur J Immunol· September 2009

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Severe tryptophan starvation blocks onset of conventional persistence and reduces reactivation of Chlamydia trachomatis.
Ralf M Leonhardt, Seung-Joon Lee, Paula B Kavathas, Peter Cresswell

Infect Immun· November 2007

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Molecular architecture of the TAP-associated MHC class I peptide-loading complex.
Elke Rufer, Ralf M Leonhardt, Michael R Knittler

J Immunol· November 2007

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Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2.
Kirstin Keusekotten, Ralf M Leonhardt, Sarah Ehses, Michael R Knittler

J Biol Chem· June 2006

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Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex.
Ralf M Leonhardt, Kirstin Keusekotten, Cemalettin Bekpen, Michael R Knittler

J Immunol· October 2005

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Functional role of C-terminal sequence elements in the transporter associated with antigen processing.
Sarah Ehses, Ralf M Leonhardt, Guido Hansen, Michael R Knittler

J Immunol· January 2005

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