Publications by authors named "Ralph Kirk"

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Novel C-7 carbon substituted fourth generation fluoroquinolones targeting N. Gonorrhoeae infections.
Ralph Kirk, Mark Betson, Matilda Bingham, Paul Doyle, Rebecca Harvey

Bioorg Med Chem Lett· October 2020

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Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection.
Victoria J Savage, Cédric Charrier, Anne-Marie Salisbury, Helen Box, Nathan Chaffer-Malam, Ralph Kirk

Antimicrob Agents Chemother· September 2016

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Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV.
Victoria J Savage, Cédric Charrier, Anne-Marie Salisbury, Emmanuel Moyo, Henry Forward, Ralph Kirk

J Antimicrob Chemother· July 2016

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Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.
Claudio Festuccia, Giovanni Luca Gravina, Andrea Mancini, Paola Muzi, Ernesto Di Cesare, Ralph Kirk

Anticancer Agents Med Chem· June 2015

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Inhibition of human α-methylacyl CoA racemase (AMACR): a target for prostate cancer.
Andrew J Carnell, Ralph Kirk, Matthew Smith, Shane McKenna, Lu-Yun Lian

ChemMedChem· October 2013

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