Publications by authors named "Ranajeet Ghose"

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Phosphorylation of a conserved aspartate in the catalytic site of eukaryotic elongation factor 2 kinase.
Andrea Piserchio, Eta A Isiorho, Rinat Abzalimov, Kevin N Dalby, Ranajeet Ghose

Protein Sci· January 2026

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The critical role of the C-terminal lobe of calmodulin in activating eukaryotic elongation factor 2 kinase.
Kimberly J Long, Luke S Browning, Andrea Piserchio, Eta A Isiorho, Mohamed I Gadallah, Ranajeet Ghose

J Biol Chem· October 2025

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Ser500 phosphorylation acts as a conformational switch to prime eEF-2K for activation.
Amanda L Bohanon, Luke S Browning, Rae M Sammons, Andrea Piserchio, Clint D J Tavares, Ranajeet Ghose

bioRxiv· July 2025

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The Critical Role of the C-terminal Lobe of Calmodulin in Activating Eukaryotic Elongation Factor 2 Kinase.
Kimberly J Long, Luke S Browning, Andrea Piserchio, Eta A Isiorho, Mohamed I Gadallah, Ranajeet Ghose

bioRxiv· May 2025

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Revealing eEF-2 kinase: recent structural insights into function.
Andrea Piserchio, Kevin N Dalby, Ranajeet Ghose

Trends Biochem Sci· February 2024

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Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor.
Andrea Piserchio, Eta A Isiorho, Kevin N Dalby, Ranajeet Ghose

J Biol Chem· June 2023

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In Science Journals.
Bianca Lopez, Di Jiang, Keith T Smith, Ian S Osborne, Phil Szuromi, Ranajeet Ghose

Science· June 2023

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ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin.
Andrea Piserchio, Kimberly J Long, Luke S Browning, Amanda L Bohanon, Eta A Isiorho, Ranajeet Ghose

Proc Natl Acad Sci U S A· April 2023

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BY-kinases: Protein tyrosine kinases like no other.
Fatlum Hajredini, Sébastien Alphonse, Ranajeet Ghose

J Biol Chem· January 2023

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Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase.
Andrea Piserchio, Eta A Isiorho, Kimberly Long, Amanda L Bohanon, Eric A Kumar, Ranajeet Ghose

Sci Adv· July 2022

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Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb.
Sébastien Alphonse, Imane Djemil, Andrea Piserchio, Ranajeet Ghose

Proc Natl Acad Sci U S A· June 2022

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A Conserved Structural Role for the Walker-A Lysine in P-Loop Containing Kinases.
Fatlum Hajredini, Ranajeet Ghose

Front Mol Biosci· October 2021

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NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity.
Sébastien Alphonse, Ankan Banerjee, Swathi Dantuluri, Stewart Shuman, Ranajeet Ghose

Nucleic Acids Res· September 2021

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An ATPase with a twist: A unique mechanism underlies the activity of the bacterial tyrosine kinase, Wzc.
Fatlum Hajredini, Ranajeet Ghose

Sci Adv· September 2021

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Structural dynamics of the complex of calmodulin with a minimal functional construct of eukaryotic elongation factor 2 kinase and the role of Thr348 autophosphorylation.
Andrea Piserchio, Kimberly Long, Kwangwoon Lee, Eric A Kumar, Rinat Abzalimov, Ranajeet Ghose

Protein Sci· June 2021

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Long-range dynamic correlations regulate the catalytic activity of the bacterial tyrosine kinase Wzc.
Fatlum Hajredini, Andrea Piserchio, Ranajeet Ghose

Sci Adv· December 2020

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The Cold-Unfolded State Is Expanded but Contains Long- and Medium-Range Contacts and Is Poorly Described by Homopolymer Models.
Natalie E Stenzoski, Junjie Zou, Andrea Piserchio, Ranajeet Ghose, Alex S Holehouse

Biochemistry· September 2020

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Keep a lid on it: A troika in kinase allostery.
Ranajeet Ghose

J Biol Chem· June 2020

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The role of calcium in the interaction between calmodulin and a minimal functional construct of eukaryotic elongation factor 2 kinase.
Kwangwoon Lee, Eric A Kumar, Kevin N Dalby, Ranajeet Ghose

Protein Sci· December 2019

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Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo.
Tamer S Kaoud, William H Johnson, Nancy D Ebelt, Andrea Piserchio, Diana Zamora-Olivares, Ranajeet Ghose

Nat Commun· November 2019

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Targeting ERK beyond the boundaries of the kinase active site in melanoma.
Rachel M Sammons, Ranajeet Ghose, Kenneth Y Tsai, Kevin N Dalby

Mol Carcinog· September 2019

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Solution Structure of the Carboxy-Terminal Tandem Repeat Domain of Eukaryotic Elongation Factor 2 Kinase and Its Role in Substrate Recognition.
Andrea Piserchio, Nathan Will, David H Giles, Fatlum Hajredini, Kevin N Dalby, Ranajeet Ghose

J Mol Biol· July 2019

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A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation.
Rachel M Sammons, Nicole A Perry, Yangmei Li, Eun Jeong Cho, Andrea Piserchio, Ranajeet Ghose

ACS Chem Biol· June 2019

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Nature of the Pre-Chemistry Ensemble in Mitogen-Activated Protein Kinases.
Ranajeet Ghose

J Mol Biol· January 2019

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Methyl NMR spectroscopy: Measurement of dynamics in viral RNA-directed RNA polymerases.
Sebastien Alphonse, Ranajeet Ghose

Methods· September 2018

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