Publications by authors named "Randy Slemmon"

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Profiling classical neuropsychiatric biomarkers across biological fluids and following continuous lumbar puncture: A guide to sample type and time.
Gallen Triana-Baltzer, Maarten Timmers, Peter De Boer, Manja Schoene, Maura Furey, Randy Slemmon

Compr Psychoneuroendocrinol· May 2022

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Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum.
Vincent Doré, James D Doecke, Ziad S Saad, Gallen Triana-Baltzer, Randy Slemmon

Alzheimers Dement (Amst)· April 2022

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Development and Validation of a High Sensitivity Assay for Measuring p217 + tau in Cerebrospinal Fluid.
Gallen Triana-Baltzer, Kristof Van Kolen, Clara Theunis, Setareh Moughadam, Randy Slemmon

J Alzheimers Dis· September 2021

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Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
Kristof Van Kolen, Thomas J Malia, Clara Theunis, Rupesh Nanjunda, Alexey Teplyakov, Randy Slemmon

J Alzheimers Dis· September 2021

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Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus.
Heikki Lukkarinen, Ina Tesseur, Darrel Pemberton, Peter Van Der Ark, Maarten Timmers, Randy Slemmon

J Alzheimers Dis· September 2021

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Development and validation of a high-sensitivity assay for measuring p217+tau in plasma.
Gallen Triana-Baltzer, Setareh Moughadam, Randy Slemmon, Kristof Van Kolen, Clara Theunis

Alzheimers Dement (Amst)· May 2021

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Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease.
Shorena Janelidze, Erik Stomrud, Ruben Smith, Sebastian Palmqvist, Niklas Mattsson, Randy Slemmon

Nat Commun· April 2020

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.
Charles F Albright, Randy C Dockens, Jere E Meredith, Richard E Olson, Randy Slemmon

J Pharmacol Exp Ther· March 2013

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A contrast in safety, pharmacokinetics and pharmacodynamics across age groups after a single 50 mg oral dose of the γ-secretase inhibitor avagacestat.
Gary Tong, Jun-Sheng Wang, Oleksandr Sverdlov, Shu-Pang Huang, Randy Slemmon

Br J Clin Pharmacol· January 2013

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Effects of single doses of avagacestat (BMS-708163) on cerebrospinal fluid Aβ levels in healthy young men.
Gary Tong, Lorna Castaneda, Jun-Sheng Wang, Oleksandr Sverdlov, Shu-Pang Huang, Randy Slemmon

Clin Drug Investig· November 2012

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A placebo-controlled, multiple ascending dose study to evaluate the safety, pharmacokinetics and pharmacodynamics of avagacestat (BMS-708163) in healthy young and elderly subjects.
Randy Dockens, Jun-Sheng Wang, Lorna Castaneda, Oleksandr Sverdlov, Shu-Pang Huang, Randy Slemmon

Clin Pharmacokinet· October 2012

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Multicenter, randomized, double-blind, placebo-controlled, single-ascending dose study of the oral γ-secretase inhibitor BMS-708163 (Avagacestat): tolerability profile, pharmacokinetic parameters, and pharmacodynamic markers.
Gary Tong, Jun-Sheng Wang, Oleksandr Sverdlov, Shu-Pang Huang, Randy Slemmon

Clin Ther· March 2012

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