Publications by authors named "Ina Tesseur"

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Longitudinal Blood-Biomarker-Based Assessment of Brain Injury in Patients Undergoing Deep Brain Stimulation and Magnetic Resonance-Guided Focused Ultrasound.
Justina Dargvainiene, Ann-Kristin Helmers, Juliana Naumann, Carl Alexander Gless, Bettina Möller, Ina Tesseur

Mov Disord· September 2025

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Concordance of Alzheimer's Disease-Related Biomarkers Between Intraventricular and Lumbar Cerebrospinal Fluid in Idiopathic Normal Pressure Hydrocephalus.
Heikki Lukkarinen, Aleksi Vanninen, Ina Tesseur, Darrel Pemberton, Peter Van Der Ark

J Alzheimers Dis· January 2023

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Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus.
Heikki Lukkarinen, Ina Tesseur, Darrel Pemberton, Peter Van Der Ark, Maarten Timmers

J Alzheimers Dis· September 2021

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Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study.
Gerald Novak, Johannes Rolf Streffer, Maarten Timmers, David Henley, H Robert Brashear, Ina Tesseur

Alzheimers Res Ther· May 2020

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Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease.
Maarten Timmers, Ina Tesseur, Jennifer Bogert, Henrik Zetterberg, Kaj Blennow

Neurobiol Aging· July 2019

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S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.
Ville Leinonen, Tuomas Rauramaa, Jarkko Johansson, Astrid Bottelbergs, Ina Tesseur

J Alzheimers Dis· June 2019

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Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study.
Maarten Timmers, Johannes Rolf Streffer, Alberto Russu, Yushin Tominaga, Hiroko Shimizu, Ina Tesseur

Alzheimers Res Ther· August 2018

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BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants.
Maarten Timmers, Soraia Barão, Bianca Van Broeck, Ina Tesseur, John Slemmon

J Alzheimers Dis· February 2018

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Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.
Ina Tesseur, Andy Nguyen, Betty Chang, Lulin Li, Nathaniel S Woodling

J Neurosci· April 2017

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Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Ira Espuny-Camacho, Amaia M Arranz, Mark Fiers, An Snellinx, Kunie Ando, Ina Tesseur

Neuron· March 2017

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Assay to probe proteolytic processing of Notch by γ-secretase.
Lutgarde Serneels, Ina Tesseur, Bart De Strooper

Methods Mol Biol· March 2015

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Regulation of amyloid precursor protein processing by serotonin signaling.
Anna A Pimenova, Amantha Thathiah, Bart De Strooper, Ina Tesseur

PLoS One· September 2014

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When the dust settles: what did we learn from the bexarotene discussion?
Ina Tesseur, Bart De Strooper

Alzheimers Res Ther· May 2014

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Amyloid and tau neuropathology differentially affect prefrontal synaptic plasticity and cognitive performance in mouse models of Alzheimer's disease.
Adrian C Lo, Emilia Iscru, David Blum, Ina Tesseur, Zsuzsanna Callaerts-Vegh

J Alzheimers Dis· April 2014

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Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500.
Adrian C Lo, Ina Tesseur, David I C Scopes, Edmund Nerou, Zsuzsanna Callaerts-Vegh

Neuropharmacology· December 2013

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Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice.
Ina Tesseur, Anna A Pimenova, Adrian C Lo, Marta Ciesielska, Stefan F Lichtenthaler

Neurobiol Aging· July 2013

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".
Ina Tesseur, Adrian C Lo, Anouk Roberfroid, Sofie Dietvorst, Bianca Van Broeck

Science· May 2013

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ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
Marcia L Moss, Gary Powell, Miles A Miller, Lori Edwards, Bin Qi, Ina Tesseur

J Biol Chem· November 2011

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The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.
Ellen Jorissen, Johannes Prox, Christian Bernreuther, Silvio Weber, Ralf Schwanbeck, Ina Tesseur

J Neurosci· April 2010

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Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3.
Ina Tesseur, Hui Zhang, Walter Brecht, Jacob Corn, Jian-Sheng Gong

J Neurochem· August 2009

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Collagen VI protects neurons against Abeta toxicity.
Jason S Cheng, Dena B Dubal, Daniel H Kim, Justin Legleiter, Irene H Cheng, Ina Tesseur

Nat Neurosci· February 2009

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Genes contributing to prion pathogenesis.
Gültekin Tamgüney, Kurt Giles, David V Glidden, Pierre Lessard, Holger Wille, Ina Tesseur

J Gen Virol· July 2008

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A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models.
Ina Tesseur, Tony Wyss-Coray

Curr Alzheimer Res· December 2006

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Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.
Ina Tesseur, Kun Zou, Luke Esposito, Frederique Bard, Elisabeth Berber

J Clin Invest· November 2006

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Highly sensitive and specific bioassay for measuring bioactive TGF-beta.
Ina Tesseur, Kun Zou, Elisabeth Berber, Hui Zhang, Tony Wyss-Coray

BMC Cell Biol· March 2006

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