Publications by authors named "Raphael Legouffe"

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Penetration Profiles of Four Topical Antifungals in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization-Fourier Transform Ion Cyclotron Resonance Imaging.
Nicolas Joly-Tonetti, Raphael Legouffe, Aurore Tomezyk, Clémence Gumez, Mathieu Gaudin

Infect Dis Ther· June 2024

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Penetration Profile of Terbinafine Compared to Amorolfine in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization-Fourier Transform Ion Cyclotron Resonance Imaging.
Nicolas Joly-Tonetti, Raphael Legouffe, Aurore Tomezyk, Clémence Gumez, Mathieu Gaudin

Infect Dis Ther· June 2024

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MALDI Mass Spectrometry Imaging and Semi-Quantification of Topically Delivered Lactic Acid.
Aaron Cohen, Raphael Legouffe, Junhong Mao, Mathieu Gaudin, David Bonnel

Skin Res Technol· October 2023

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Correction: Wind et al. Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial. 2022, , 1510.
Selinde S Wind, Manon A A Jansen, Melanie Rijsbergen, Michiel J van Esdonk, Dimitrios Ziagkos, Raphael Legouffe

Cancers (Basel)· February 2023

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Tumor Distribution by Quantitative Mass Spectrometry Imaging of the Inhibitor of Apoptosis Protein Antagonist Xevinapant in Patients with Resectable Squamous Cell Carcinoma of the Head and Neck (EudraCT Number: 2014-004655-31).
Annick Menetrey, Raphael Legouffe, Amina Haouala, David Bonnel, Elisabeth Rouits

Anal Chem· September 2022

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Hyaluronic acid detection and relative quantification by mass spectrometry imaging in human skin tissues.
Raphael Legouffe, Olivier Jeanneton, Mathieu Gaudin, Aurore Tomezyk, Amandine Gerstenberg

Anal Bioanal Chem· August 2022

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GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma modulation of lysosomal functions.
Sonia Brun, Eloïne Bestion, Eric Raymond, Firas Bassissi, Zuzana Macek Jilkova, Raphael Legouffe

Autophagy· March 2022

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Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial.
Selinde S Wind, Manon A A Jansen, Melanie Rijsbergen, Michiel J van Esdonk, Dimitrios Ziagkos, Raphael Legouffe

Cancers (Basel)· March 2022

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MALDI imaging facilitates new topical drug development process by determining quantitative skin distribution profiles.
David Bonnel, Raphaël Legouffe, André H Eriksson, Rasmus W Mortensen, Fabien Pamelard

Anal Bioanal Chem· April 2018

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A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.
Françoise Brignole-Baudouin, Nicolas Desbenoit, Gregory Hamm, Hong Liang, Jean-Pierre Both, Raphael Legouffe

PLoS One· June 2013

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Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor.
Gregory Hamm, David Bonnel, Raphael Legouffe, Fabien Pamelard, Jean-Marie Delbos

J Proteomics· August 2012

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MALDI imaging techniques dedicated to drug-distribution studies.
David Bonnel, Raphael Legouffe, Nicolas Willand, Alain Baulard, Gregory Hamm

Bioanalysis· June 2011

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