Publications by authors named "Raquel Alvarez"

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A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial.
Alexander Zarbock, Marlies Ostermann, Lui Forni, Christian Bode, Lennart Wild

Lancet· December 2025

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Loss of function of FAM177A1, a Golgi complex localized protein, causes a novel neurodevelopmental disorder.
Jennefer N Kohler, Nicole R Legro, Dustin Baldridge, Jimann Shin, Angela Bowman, Raquel Alvarez

Genet Med· September 2024

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Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents.
Raúl Fuentes-Martín, Pilar Ayuda-Durán, Robert Hanes, Laura Gallego-Yerga, Lisanne Wolterinck

Eur J Med Chem· September 2024

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Experimental structure based drug design (SBDD) applications for anti-leishmanial drugs: A paradigm shift?
Miguel Marín, Marta López, Laura Gallego-Yerga, Raquel Álvarez, Rafael Peláez

Med Res Rev· May 2024

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Frentizole, a Nontoxic Immunosuppressive Drug, and Its Analogs Display Antitumor Activity via Tubulin Inhibition.
Sergio Ramos, Alba Vicente-Blázquez, Marta López-Rubio, Laura Gallego-Yerga, Raquel Álvarez

Int J Mol Sci· December 2023

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Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy.
Myriam González, Younes Ellahioui, Laura Gallego, Alba Vicente-Blázquez, Raquel Álvarez

Bioorg Chem· February 2023

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Effectiveness, Toxicity, and Survival Predictors of Regorafenib in Metastatic Colorectal Cancer: A Multicenter Study of Routinely Collected Data.
Alberto Calvo-García, María Pérez Abánades, Silvia Ruíz-García, Ana Beatriz Fernández Román, Javier Letellez Fernández

Oncology (Williston Park)· December 2022

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IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function.
Maya E Kotas, Camille M Moore, Jose G Gurrola, Steven D Pletcher, Andrew N Goldberg, Raquel Alvarez

JCI Insight· July 2022

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New diarylsulfonamide inhibitors of Leishmania infantum amastigotes.
Myriam González, Pedro José Alcolea, Raquel Álvarez, Manuel Medarde, Vicente Larraga

Int J Parasitol Drugs Drug Resist· August 2021

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Polymer Conjugation of Docosahexaenoic Acid Potentiates Cardioprotective Therapy in Preclinical Models of Myocardial Ischemia/Reperfusion Injury.
Sandra Tejedor, Irene Dolz-Pérez, Caitlin G Decker, Amparo Hernándiz, Jose L Diez

Adv Healthc Mater· May 2021

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Psychiatric relapse following a phone app intervention: A case report.
Alejandro Porras-Segovia, Javier López-Moriñigo, Raquel Álvarez, Isaac Díaz-Oliván, Verónica González

Psychiatry Res· April 2021

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Microtubule Destabilizing Sulfonamides as an Alternative to Taxane-Based Chemotherapy.
Myriam González, María Ovejero-Sánchez, Alba Vicente-Blázquez, Raquel Álvarez, Ana B Herrero

Int J Mol Sci· February 2021

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Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents.
Raquel Álvarez, Laura Aramburu, Consuelo Gajate, Alba Vicente-Blázquez, Faustino Mollinedo

Eur J Med Chem· January 2021

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Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.
Raquel Álvarez, Laura Aramburu, Consuelo Gajate, Alba Vicente-Blázquez, Faustino Mollinedo

Bioorg Chem· May 2020

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Alkynyl Gold(I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer.
Inés Mármol, Pilar Castellnou, Raquel Alvarez, M Concepción Gimeno, M Jesús Rodríguez-Yoldi

Eur J Med Chem· December 2019

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The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors.
Myriam González, Younes Ellahioui, Raquel Álvarez, Laura Gallego-Yerga, Esther Caballero

Molecules· November 2019

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Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target.
Alba Vicente-Blázquez, Myriam González, Raquel Álvarez, Sara Del Mazo, Manuel Medarde

Med Res Rev· May 2019

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Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells.
Raquel Álvarez, Consuelo Gajate, Pilar Puebla, Faustino Mollinedo, Manuel Medarde

Eur J Med Chem· October 2018

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Bioactive Heterometallic Cu-Zn Complexes with Potential Biomedical Applications.
Ishani Majumder, Prateeti Chakraborty, Raquel Álvarez, Myriam Gonzalez-Diaz, Rafael Peláez

ACS Omega· October 2018

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Origin and evolution of chloroplast group I introns in lichen algae.
Alicia Del Hoyo, Raquel Álvarez, Francisco Gasulla, Leonardo Mario Casano, Eva María Del Campo

J Phycol· February 2018

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Effects of pneumoperitoneum on severe hypernatremia in an adult patient who underwent laparoscopic surgery of hydatid cysts.
Diego Anta, José M Beleña, Raquel Álvarez, Mónica Núñez

J Clin Anesth· February 2017

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New ligands of the tubulin colchicine site based on X-ray structures.
Raquel Álvarez, Manuel Medarde, Rafael Peláez

Curr Top Med Chem· August 2015

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Differences in the cell walls and extracellular polymers of the two Trebouxia microalgae coexisting in the lichen Ramalina farinacea are consistent with their distinct capacity to immobilize extracellular Pb.
Leonardo M Casano, Marcia R Braga, Raquel Álvarez, Eva M Del Campo, Eva Barreno

Plant Sci· July 2015

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Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins.
Carmen Jiménez, Younes Ellahioui, Raquel Álvarez, Laura Aramburu, Alejandra Riesco

Eur J Med Chem· July 2015

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