Publications by authors named "Ravi Tharakan"

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A general assay platform to study protein pharmacology using ligand-dependent structural dynamics.
Daniel A Ciulla, Patricia K Dranchak, Mahesh Aitha, Renier H P van Neer, Divia Shah, Ravi Tharakan

Nat Commun· May 2025

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Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders.
Vukasin M Jovanovic, Narisu Narisu, Lori L Bonnycastle, Ravi Tharakan, Kendall T Mesch

bioRxiv· September 2024

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Methotrexate-based PROTACs as DHFR-specific chemical probes.
Sandeep Rana, Patricia Dranchak, Jayme L Dahlin, Laurence Lamy, Wenqing Li, Ravi Tharakan

Cell Chem Biol· February 2024

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Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.
Ravi Tharakan, Ceereena Ubaida-Mohien, Christopher Dunn, Mary Kaileh, Rakel Tryggvadottir

Aging Cell· July 2023

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Understanding the Human Aging Proteome Using Epidemiological Models.
Ceereena Ubaida-Mohien, Ruin Moaddel, Zenobia Moore, Pei-Lun Kuo, Ravi Tharakan

Methods Mol Biol· May 2022

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Ribosome profiling analysis of human skeletal muscle identifies reduced translation of mitochondrial proteins with age.
Ravi Tharakan, Ceereena Ubaida-Mohien, Yulan Piao, Myriam Gorospe, Luigi Ferrucci

RNA Biol· November 2021

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Minireview: Novel Micropeptide Discovery by Proteomics and Deep Sequencing Methods.
Ravi Tharakan, Akira Sawa

Front Genet· May 2021

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Proteomics and Epidemiological Models of Human Aging.
Ceereena Ubaida-Mohien, Ruin Moaddel, Ann Zenobia Moore, Pei-Lun Kuo, Faraz Faghri, Ravi Tharakan

Front Physiol· May 2021

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Translational Control during Cellular Senescence.
Matthew J Payea, Carlos Anerillas, Ravi Tharakan, Myriam Gorospe

Mol Cell Biol· January 2021

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Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study.
Ravi Tharakan, Ceereena Ubaida-Mohien, Ann Zenobia Moore, Dena Hernandez, Toshiko Tanaka

J Gerontol A Biol Sci Med Sci· October 2020

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A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics.
Ravi Tharakan, Simion Kreimer, Ceereena Ubaida-Mohien, Joelle Lavoie, Volodimir Olexiouk

Neurosci Res· February 2020

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Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria.
Ceereena Ubaida-Mohien, Alexey Lyashkov, Marta Gonzalez-Freire, Ravi Tharakan, Michelle Shardell

Elife· October 2019

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Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients.
Ceereena Ubaida-Mohien, Benjamin Lamberty, Alex M Dickens, Michelle M Mielke, Thomas Marcotte, Ravi Tharakan

AIDS· June 2017

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Integrated microfluidic chip and online SCX separation allows untargeted nanoscale metabolomic and peptidomic profiling.
Ravi Tharakan, Dingyin Tao, Ceereena Ubaida-Mohien, Rhoel R Dinglasan, David R Graham

J Proteome Res· March 2015

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Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data.
Jürgen Hartler, Ravi Tharakan, Harald C Köfeler, David R Graham, Gerhard G Thallinger

Brief Bioinform· May 2013

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Data maximization by multipass analysis of protein mass spectra.
Ravi Tharakan, Nathan Edwards, David R M Graham

Proteomics· March 2010

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OMSSAGUI: An open-source user interface component to configure and run the OMSSA search engine.
Ravi Tharakan, Lennart Martens, Jennifer E Van Eyk, David R Graham

Proteomics· June 2008

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